Results 71 to 80 of about 3,629 (180)

Generalised absence seizures in Cavalier King Charles Spaniels presenting with paroxysms: eight cases (2016‐2025)

Journal of Small Animal Practice, EarlyView.
Objectives To describe the clinical and electroencephalographic findings associated with absence seizures in a population of Cavalier King Charles Spaniels. Materials and Methods This was a retrospective descriptive case series of Cavalier King Charles Spaniels diagnosed with absence seizures at two veterinary referral hospitals between 2016 and 2025 ...
R. Paterson, C. McKenna, G. Kadler, M. Arsenault, G. Mallet, A. Chan, V. Sammut, G. Leblond, S. Lim, M. Cortez, F. James   +10 more
wiley   +1 more source

A randomised trial of a medium-chain TAG diet as treatment for dogs with idiopathic epilepsy [PDF]

, 2015
Despite appropriate antiepileptic drug treatment, approximately one-third of humans and dogs with epilepsy continue experiencing seizures, emphasising the importance for new treatment strategies to improve the quality of life of people or dogs with ...
Brian Zanghi, Dahlin, Elizabeth Want, Emma S. S. Davies, Engel, Geyelin, Holger A. Volk, Lowrie, Masino, Patterson, Piotr, Piotr, Schwartz, Schwartz-Porsche, Thigpen, Tsz Hong Law, Wilder, Yuanlong Pan   +17 more
core   +3 more sources

A Multi‐Institutional Retrospective Study of 21 Dogs Having Undergone Hypofractionated Radiotherapy for Adrenal Tumours (2017–2024)

Veterinary and Comparative Oncology, Volume 24, Issue 2, Page 229-239, June 2026.
ABSTRACT Radiation therapy (RT) has emerged as a promising non‐surgical approach for treating canine adrenal tumours. This multi‐institutional, retrospective study describes clinical outcomes for 21 dogs having been prescribed a course of hypofractionated image‐guided intensity‐modulated RT (IMRT) entailing delivery of 25–35 Gy total in 5 fractions ...
Yen‐Hao Erik Lai, Michael S. Kent, Michael W. Nolan, Dah‐Renn Fu, Jayme S. Looper   +4 more
wiley   +1 more source

Whole blood trace element and toxic metal concentration in dogs with idiopathic epilepsy and healthy dogs: A case-control study

Frontiers in Veterinary Science, 2023
BackgroundIdiopathic epilepsy (IE) is the most common neurological disease in dogs. Multiple genes and environmental factors interact to cause clinical signs, although the pathogenesis remains poorly understood.
Sarah Rosendahl, Johanna Anturaniemi, Tiina-Kaisa Kukko-Lukjanov, Kristiina A. Vuori, Robin Moore, Manal Hemida, Anne Muhle, Anna Hielm-Björkman   +7 more
doaj   +1 more source

High Frequency of a Single Nucleotide Substitution (c.-6-180T>G) of the CanineMDR1/ABCB1Gene Associated with Phenobarbital-Resistant Idiopathic Epilepsy in Border Collie Dogs [PDF]

Disease Markers, 2013
A single nucleotide substitution (c.-6-180T>G) associated with resistance to phenobarbital therapy has been found in the canineMDR1/ABCB1gene in Border Collies with idiopathic epilepsy. In the present study, a PCR-restriction fragment length polymorphism assay was developed for genotyping this mutation, and a genotyping survey was carried out in a ...
Keijiro Mizukami, Akira Yabuki, Hye-Sook Chang, Mohammad Mejbah Uddin, Mohammad Mahbubur Rahman, Kazuya Kushida, Moeko Kohyama, Osamu Yamato   +7 more
openaire   +2 more sources

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu, Alex Liang, Benjamin U. Hoffman, Dawn M. Schiehser, Oliver Case, Alan Simmons, Ruth Klaming, Andres Gottfried‐Blackmore, Ravinder K. Mittal, Christopher Puleo, Hubert Lim, Imanuel Lerman   +11 more
wiley   +1 more source

Case Report: Embedding “Digital Chronotherapy” Into Medical Devices—A Canine Validation for Controlling Status Epilepticus Through Multi-Scale Rhythmic Brain Stimulation

Frontiers in Neuroscience, 2021
Circadian and other physiological rhythms play a key role in both normal homeostasis and disease processes. Such is the case of circadian and infradian seizure patterns observed in epilepsy. However, these rhythms are not fully exploited in the design of
Mayela Zamora, Sebastian Meller, Filip Kajin, James J. Sermon, James J. Sermon, Robert Toth, Moaad Benjaber, Moaad Benjaber, Derk-Jan Dijk, Derk-Jan Dijk, Rafal Bogacz, Gregory A. Worrell, Antonio Valentin, Benoit Duchet, Holger A. Volk, Timothy Denison, Timothy Denison   +16 more
doaj   +1 more source

Antiepileptic drugs’ tolerability and safety – a systematic review and meta-analysis of adverse effects in dogs [PDF]

, 2016
Various anti-epileptic drugs (AEDs) are used for the management of idiopathic epilepsy (IE) in dogs. Their safety profile is an important consideration for regulatory bodies, owners and prescribing clinicians.
A Stabile, A-MOL-V Kiviranta, AA Shukralla, AE Chauvet, AK Cook, AS Nash, B Dayrell-Hart, B Mackay, C Rundfeldt, CL Gaskill, CL Gaskill, CR Hooijmans, D Moher, D Ruehlmann, D Schwartz-Porsche, D Schwartz-Porsche, David C. Brodbelt, DE Bevier, DJ Meyer, DJ Weiss, DJ Weiss, DJU Schwartz-Porsche, DM Boothe, DM Boothe, DM Conning, E Bersan, E Ernst, E Perucca, E Thrift, EM Poffenbarger, F Sturtevant, G Habock, G Jacobs, G Zaccara, G Zaccara, GC Farnbach, HA Volk, HE Baird-Heinz, Holger A. Volk, J Speciale, JA Berlin, JC Mathis, JF Summers, JG Cunningham, JH McGee, JH Rossmeisl, JK Aronson, JM Steiner, KR Dyer, L Aagaard, LAPA Nafe, LB Kantrowitz, LC Paull, LG Cuervo, LK Pearce, M Charalambous, M Govendir, M Jambroszyk, M Podell, M Raw, M Srivastava, MA Holmes, Marios Charalambous, MFD Steinberg, MH Litchfield, ML Miller, MM Aitken, N Andric, N Shaw, NA Boynosky, PA March, PB Muller, PM Henricks, PN Papanikolaou, PN Papanikolaou, R Bracchi, R Chou, RM Turner, RM Walker, S Daminet, S Derry, S Golder, S Golder, S Rieck, S Steinmetz, S Wieland, SA Kube, SA Moore, Sara K. Shivapour, SD Ross, SE Bunch, SE Bunch, SE Bunch, SE Bunch, SE Yohn, SF Foster, T Klopmann von, T Klopmann von, T Klopmann von, VJ Navarro, W Loscher, W Loscher, Y Chang, Y Heynold, YK Loke, YK Loke   +105 more
core   +3 more sources

Investigation of association between serum C‐reactive protein concentrations and proteinuria in dogs

Journal of Small Animal Practice, Volume 67, Issue 3, Page 235-242, March 2026.
Objectives Identify if serum C‐reactive protein concentrations and specific diseases are associated with proteinuria (defined as urine protein:creatinine ratio >0.2) in dogs without known pathological pre‐renal, renal or post‐renal causes. Materials and Methods Hypothesis generating retrospective study.
E. Ruane, M. M. A. Rodgers, C. H. Z. Hare, K. E. McCallum, T. L. Williams   +4 more
wiley   +1 more source

Electroencephalography recording analysis in monitoring of canine idiopathic epilepsy treated with phenobarbital. Pilot study

Polish Journal of Veterinary Sciences, 2014
Abstract EEG recording is used in veterinary medicine as a diagnostic tool to support clinical diagnosis of idiopathic epilepsy and to identify focal seizure activity. This retrospective study was designed to compare EEG procedures in 23 dogs with idiopathic epilepsy before and after phenobarbital treatment.
A, Bocheńska, M, Kwiatkowska, A, Pomianowski, T, Monowid, Z, Adamiak   +4 more
openaire   +2 more sources