Results 61 to 70 of about 33,316 (204)

Origins and Evolutionary Dynamics of H3N2 Canine Influenza Virus [PDF]

Journal of Virology, 2015
ABSTRACT Influenza A viruses (IAVs) are maintained mainly in wild birds, and despite frequent spillover infections of avian IAVs into mammals, only a small number of viruses have become established in mammalian hosts. A new H3N2 canine influenza virus (CIV) of avian origin emerged in Asia in the mid-2000s and is now circulating in dog ...
Henan, Zhu, Joseph, Hughes, Pablo R, Murcia   +2 more
openaire   +2 more sources

Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation

BMEMat, EarlyView.
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu, Nan Xu, Xin Li, Xiaowo Kang, Tieyuan Bian, Junsheng Lin, Hao Tang, Yinyin Bao, Lu Zhang, Hongyan Yuan, Mingxi Yao, Xingyu Jiang, Zhi Luo   +12 more
wiley   +1 more source

The mouse and ferret models for studying the novel avian-origin human influenza A (H7N9) virus. [PDF]

, 2013
BackgroundThe current study was conducted to establish animal models (including mouse and ferret) for the novel avian-origin H7N9 influenza virus.FindingsA/Anhui/1/2013 (H7N9) virus was administered by intranasal instillation to groups of mice and ...
Bao, Linlin, Chen, Ting, Deng, Wei, Gao, Kai, Huang, Lan, Li, Fengdi, Li, Yanhong, Liu, Jiangning, Lv, Qi, Qin, Chuan, Wei, Qiang, Xiang, Zhiguang, Xu, Lili, Xu, Yanfeng, Yao, Yanfeng, Yong, Weidong, Yu, Pin, Yuan, Jing, Zhang, Lianfeng, Zhu, Hua   +19 more
core   +3 more sources

THE SYNERGISM OF HUMAN INFLUENZA AND CANINE DISTEMPER VIRUSES IN FERRETS [PDF]

Journal of Experimental Medicine, 1940
The infections produced in ferrets by human influenza virus and canine distemper virus were studied. Cross immunity and cross neutralization tests showed that these two viruses were not related antigenically. Ferrets infected with influenza virus alone rapidly produced considerable quantities of neutralizing antibodies, and after the 6th day virus was ...
F L, Horsfall, E H, Lennette
openaire   +2 more sources

Shaping Function: Polymeric 3D Systems With Unconventional Geometries for Biomedical Applications

Small, EarlyView.
Particle shape is a key design parameter governing biological interactions. Advances in fabrication enable precise control over anisotropy and compartmentalization, allowing modulation of cellular uptake, transport, and biodistribution, ultimately enhancing therapeutic performance. ABSTRACT Polymer geometry is a primary determinant of physical behavior
Francisca G. Perfeito, Mariana B. Oliveira, João F. Mano   +2 more
wiley   +1 more source

High-Throughput MicroRNA Profiles of Permissive Madin-Darby Canine Kidney Cell Line Infected with Influenza B Viruses

Viruses, 2019
Victoria and Yamagata lineages of influenza B viruses are globally circulating in seasonal epidemics. Madin−Darby canine kidney (MDCK) cells are permissive for viral isolation and vaccine manufacture. Nevertheless, the interplay between influenza B
Suthat Saengchoowong, Kritsada Khongnomnan, Witthaya Poomipak, Kesmanee Praianantathavorn, Yong Poovorawan, Qibo Zhang, Sunchai Payungporn   +6 more
doaj   +1 more source

Big data in veterinary medicines regulation: A data landscape analysis to support regulatory activities

Veterinary Record, EarlyView.
Abstract Background This study describes the development of a data landscape analysis protocol that identifies and characterises animal health data sources to support key regulatory activities throughout the life cycle of veterinary medicines. Methods The protocol included: development of criteria to identify data sources; selection of variables to ...
Ewa Pacholewicz, Eduardo de Freitas Costa, Mariana Avelino de Souza Santos, Bjorn Berendsen, Jos A. A. M. Verstegen   +4 more
wiley   +1 more source

Comparison of the virulence and transmissibility of canine H3N2 influenza viruses and characterization of their canine adaptation factors [PDF]

Emerging Microbes & Infections, 2018
Recent canine influenza outbreaks have raised concerns about the generation of pathogenic variants that may pose a threat to public health. Here, we examine avian-like H3N2 canine influenza viruses (CIVs) isolated from 2009 to 2013 in South Korea from dogs.
Lee, In-Won, Kim, Young-Il, Lim, Gyo-Jin, Kwon, Hyeok-Il, Si, Young-Jae, Park, Su-Jin, Kim, Eun-Ha, Kim, Se Mi, Nguyen, Hiep Dinh, Song, Min-Suk, Choi, Young-Ki   +10 more
openaire   +2 more sources

Prevalence of Eight Viruses in Captive Amur Tigers (Panthera tigris altaica) From Harbin, China 中国哈尔滨市圈养东北虎8种病毒的流行

Wildlife Letters, EarlyView.
The Amur tiger, an endangered flagship species mainly found in the Russia Far East and Northeastern China, holds immense biological importance, and has been listed under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES).
Wei Xie, Luyao Wang, Mengna Chen, Qinjie Chang, Hongyu Jiang, Haitao Xu, Liu Dan, Xiang Li, Yulong Wang, Xiangwei Zeng, Bin Yang, Miaowei Wang, Yonggang Jiang, Hongliang Chai, Siyuan Yang, Yajun Wang   +15 more
wiley   +1 more source

Circulation of influenza viruses in the dog population in Kazakhstan (2023-2024)

Open Veterinary Journal
Background: Dogs in close contact with humans can serve as a source of potentially dangerous reassortant influenza viruses with zoonotic potential. The dog's body can serve as a vessel for the emergence of new influenza viruses.
Tatyana Glebova, Nailya Klivleyeva, Nurbol Saktaganov, Mira Shamenova, Galina Lukmanova, Assem Baimukhametova, Sagadat Baiseiit, Nuray Ongarbayeva, Kanat Orynkhanov, Anna Ametova, Aitolkyn Ilicheva   +10 more
doaj   +1 more source