Results 101 to 110 of about 1,736,990 (170)

TP53 gene expression levels and tumor aggressiveness in canine mammary carcinomas

, 2017
The protein p53 is considered to be one of the most important tumor suppressor factors. Despite this importance, a potential association between TP53 messenger (m)RNA levels and tumor aggressiveness has not been well defined in animal cancer.
Agnes Marie S. Figueiredo, Tábata Maués, Maria de Lourdes G. Ferreira, Ana Maria R. Ferreira, Marcela F. V. de Mello, Kênia B. El-Jaick, Mariana S. Ramundo, Táya F. Oliveira   +7 more
core   +1 more source

Simvastatin exhibits antiproliferative effects on spheres derived from canine mammary carcinoma cells [PDF]

, 2015
Mammary cancer is the most frequent type of tumor in the female canine. Treatments are mainly limited to surgery and chemotherapy; however, these tumors may develop clinical recurrence, metastasis and chemoresistance.
Olivares, Araceli, Stoore, Caroll, Torres, Cristian G.   +2 more
core   +1 more source

Matrine Targets BTF3 to Inhibit the Growth of Canine Mammary Tumor Cells

, 2023
The canine mammary tumor model is more suitable for studying human breast cancer, and the safety concentrations of matrine and the biotin-labeled matrine probe were determined in canine primary mammary epithelial cells, and then selected canine mammary ...
Zijian Feng, Huizhen Yang, Hua Zhang, Wei Yin, Hongquan Li, Yaogui Sun, Fida Noor, Zhenbiao Zhang, Panpan Sun, Jia Zhong, Kuohai Fan, Na Sun   +11 more
core   +1 more source

Expression and significance of CHIP in canine mammary gland tumors

Journal of Veterinary Medical Science, 2015
CHIP (Carboxy terminus of Hsc70 Interacting Protein) is an E3 ubiquitin ligase that can induce ubiquitination and degradation of several oncogenic proteins. The expression of CHIP is frequently lower in human breast cancer than in normal breast tissue. However, the expression and role of CHIP in the canine mammary gland tumor (CMGT) remain unclear.
WANG, Huanan, YANG, Xu, JIN, Yipeng, PEI, Shimin, ZHANG, Di, MA, Wen, HUANG, Jian, QIU, Hengbin, ZHANG, Xinke, JIANG, Qiuyue, SUN, Weidong, ZHANG, Hong, LIN, Degui   +12 more
openaire   +3 more sources

DEVELOPMENT, ANATOMY, HISTOLOGY, LYMPHATIC DRAINAGE, CLINICAL FEATURES, AND CELL DIFFERENTIATION MARKERS OF CANINE MAMMARY GLAND NEOPLASMS.

, 2010
Mammary neoplasms are the most common neoplasm in female dogs. This article describes the embryologic development, normal anatomy, and histology of the canine mammary gland from the onset of first estrous and the changes that occur in the mammary gland ...
RASOTTO R, GOLDSCHMIDT MH, ZAPPULLI, VALENTINA ELENA GIUDITTA, SORENMO KU, R. Rasotto, M. H. Goldschmidt, K. U. Sorenmo, V. Zappulli   +7 more
core   +2 more sources

CMLPS-N1: a novel preclinical cell line model for canine mammary tumor and its application in therapeutic screening

Veterinary Quarterly
Canine mammary tumor is the most common tumor in intact female dogs and poses a growing health burden due to its high malignancy rate and increasing canine populations.
Xiao Wang, Han Zhou, Qian Zhang, Yihan Liu, Lixin He, Wenxuan Li, Bin Ma, Lihong Luo, Lijun Guo, Changwei Qiu   +9 more
doaj   +1 more source

Expression of prolactin receptors in normal canine mammary tissue, canine mammary adenomas and mammary adenocarcinomas [PDF]

, 2012
Background Mammary tumors represent the most common neoplastic disease in female dogs. Recently, the promoting role of prolactin (PRL) in the development of human breast carcinoma has been shown.
Guscetti, Franco; https://orcid.org/, Kowalewski Mariusz P, Carla Bley, Erika ErikaMichel, Rohrer Bley, Carla; https://orcid.org/, Bley Carla, Feldmann Stefanie K, Michel, Erika, Erika Michel, Kowalewski, Mariusz P; https://orcid.org/, Reichler, Iris M; https://orcid.org/, Mariusz P Kowalewski, Boos Alois, Boos, Alois; https://orcid.org/, Carla Rohrer Bley, Feldmann, S K, Reichler Iris M, Alois Boos, Guscetti Franco, Michel, E, Stefanie K Feldmann, Franco Guscetti, Michel Erika, Iris M Reichler, Boos A, Feldmann SK, Reichler IM, Bley CR, Michel E, Guscetti F, Kowalewski MP, Feldmann, Stefanie K   +31 more
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The Relationship of Tumor Microbiome and Oral Bacteria and Intestinal Dysbiosis in Canine Mammary Tumor

, 2022
Canine mammary tumor (CMT) is the most common tumor in dogs, with 50% of malignant cases, and lacks an effective therapeutic schedule, hence its early diagnosis is of great importance to achieve a good prognosis.
Chong-Tao Du, Tang, Xin-Yue, Gao, Wei, Chao Yu, Zhang, Yu-Zhu, Yu-Zhu Zhang, Xie, Guang-Hong, Guang-Hong Xie, Huang, Rong-Lei, Hui-Hua Zheng, Xin-Yue Tang, Zheng, Hui-Hua, Yu, Chao, Du, Chong-Tao, Rong-Lei Huang, Wei Gao   +15 more
core   +1 more source

Classification and grading of canine malignant mammary tumors.

Veterinary research forum : an international quarterly journal, 2013
Histological grading is a good parameter to stratify tumors according to their biological aggressiveness. The Elston and Ellis grading method in humans, invasive ductal breast carcinomas and other invasive tumors are routinely used. The aims of this study were classification of mammary gland tumors and also application of a human grading method in ...
Abbas Tavasoly, Hannaneh Golshahi, Annahita Rezaie, Mohammad Farhadi   +3 more
openaire   +2 more sources

Epidemiological investigation and surgical treatment of canine mammary tumors in Dalian, China, from 2019 to 2023.

PLoS ONE
Objective of this study is to investigate the epidemiological characteristics, clinical features, and treatment outcomes of canine mammary tumors in Dalian, providing insights into prevention and management strategies.
Zheng Jing, Jiawang Feng, Hongyan Jin
doaj   +1 more source