Results 141 to 150 of about 31,037 (228)

Cannabidiol level in hemp (\kur{Cannabis sativa})

open access: yes, 2013
Hemp (Cannabis sativa) is a crop that people have grown for a lot of years ago. It is amazing by its almost versatile use, whether in medicine, food, industry and power engineering.
BOUDOVÁ, Miroslava
core  

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos   +7 more
wiley   +1 more source

Perspectives in biomedicine: Superfoods and antioxidant power classification

open access: yesThe Canadian Journal of Chemical Engineering, Volume 104, Issue 12, Page 6393-6402, December 2026.
Abstract The market value of natural food antioxidants will double to 8 billion USD by 2033, driven by a global consumer demand for ‘clean label’ products and proactive wellness solutions. However, the industrial application and health labelling (commercial brands) of these compounds remain severely constrained by inconsistent analytical methods.
Domenico Fuoco, Gregory S. Patience
wiley   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

open access: yesArthritis Care &Research, Volume 78, Issue 11, Page 1791-1800, November 2026.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang   +10 more
wiley   +1 more source

Advances in Multidimensional Molecular Mechanisms of Epilepsy and Precision Therapy Strategies

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
Epilepsy arises from a multidimensional network imbalance, integrating genetic, inflammatory, and metabolic disruptions. This complexity drives neuronal hyperexcitability and underpins therapeutic challenges. Our review highlights how emerging precision strategies, from targeted molecular therapies to neuromodulation, offer a transformative path toward
Yimin Han   +7 more
wiley   +1 more source

Beneficial Role of Natural Polyphenols Against Epilepsy: Greasing the Wheels of Pharmacotherapy Research for Epilepsy

open access: yesFood Frontiers, Volume 7, Issue 6, November 2026.
ABSTRACT Epilepsy is the most disabling neurological disease that affects all economic classes, age groups, regions, and races. Although many antiseizure drugs are approved for epilepsy treatment, they fail to work in about 30%–40% of patients. Thus, there is a great need to identify better pharmacological agents to treat epilepsy.
Janakiraman Pillai Udaiyappan   +3 more
wiley   +1 more source

The Development of a Simple Liquid Chromatography‐Precursor Ion Scan‐Mass Spectrometry Screening Method for the Detection of Phytocannabinoids in Plant Extracts

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 11, November 2026.
ABSTRACT Screening of major cannabinoids in cannabis‐derived extracts is needed when these extracts are applied in pharmacological and biological studies. Precursor ion scan‐mass spectrometry (PIS‐MS) is a viable approach for the detection and screening of major cannabinoids through characteristic MS/MS fragmentation behavior.
Radwa Mahmoud   +5 more
wiley   +1 more source

Global Prognostic Impact of Substance Use in Alcohol‐Associated Hepatitis

open access: yesAlcohol, Clinical and Experimental Research, Volume 50, Issue 11, November 2026.
Alcohol‐associated hepatitis (AH) carries high short‐term mortality, yet behavioral risk factors are not captured by current prognostic models. In this multinational cohort of 814 patients, active cannabis use independently predicted mortality after accounting for liver disease severity and transplantation as a competing‐risk.
Omar Albhaisi   +49 more
wiley   +1 more source

Molecular Basis for Activation to Inhibition Switching in Kv7.2 Channel Modulators

open access: yesAngewandte Chemie, Volume 138, Issue 42, 12 October 2026.
The paper describes the serendipitous discovery of chemical manipulation allowing the activator‐to‐inhibitor switching in Kv7.2 channel modulators. The molecular determinants driving this switch have been rationalized by multidisciplinary investigation encompassing synthetic and analytical chemistry, in silico methods, cryo‐EM analysis ...
Tania Ciaglia   +20 more
wiley   +2 more sources

Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta‐analysis

open access: yesAddiction, Volume 121, Issue 11, Page 2897-2958, November 2026.
Abstract Background and aims Cocaine use disorder (CUD) is an increasingly widespread concern worldwide. Various pharmacological treatments have been investigated for CUD, but their efficacy remains unclear, and none have been licensed for treatment.
Craig Paterson   +13 more
wiley   +1 more source

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