Results 151 to 160 of about 29,527 (256)

Transfer of paracetamol across the placenta and fetal blood–brain barriers and its safety for use in pregnancy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley   +1 more source

Antidepressant-like effects of cannabidiol when combined with temozolomide in adult rats. [PDF]

open access: yesFront Pharmacol
Gálvez-Melero L   +3 more
europepmc   +1 more source

Infralimbic cannabidiol infussion : Effects on behavior and celular activation

open access: yes, 2018
Background. Systemic administration of cannabidiol, a non-psychotomimetic component of Cannabis sativa, induces a rapid and maintained antidepressant effect in an animal model of depression.
Gómez Acero, Laura
core  

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos   +7 more
wiley   +1 more source

Current Knowledge on Phytoremediation Potential of Industrial Hemp (Cannabis sativa L.) for PFAS and Heavy Metal Contaminated Soils

open access: yesRemediation Journal, Volume 36, Issue 2, Spring 2026.
ABSTRACT This review synthesizes current research on the phytoremediation potential of industrial hemp (Cannabis sativa L.) for heavy metals, including arsenic, aluminium, mercury, copper, lead, cadmium, nickel, and zinc, as well as per‐ and polyfluoroalkyl substances (PFAS), commonly referred to as “forever chemicals.” A structured and transparent ...
Omid Ansari, Luca De Prato
wiley   +1 more source

Mitochondrial Fusion and Fission in Age‐Related Cardio‐Cerebral Diseases: Mechanisms and Interventions

open access: yesAging Cell, Volume 25, Issue 10, October 2026.
Mitochondrial fission‐fusion imbalance contributes to age‐related cardio‐cerebral diseases like Alzheimer's disease, Parkinson's disease, Cerebral Infarction, Arteriosclerosis, Myocardial Infarction, Cardiac valve disease, Hypertension, and Cardiomyopathy. This review summarizes its regulatory mechanisms and interventions.
Yuyao Yin, Zijian Li
wiley   +1 more source

Computational and Comparative In Vitro Evaluation of GC–MS Profiled Cannabis sativa Inflorescence Extracts’ Metabolites on Selected Diabetes Therapeutic Targets

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Cannabis sativa inflorescence extracts demonstrate promising antidiabetic potential through enzyme inhibition, antioxidant activity, and molecular docking. The hexane extract exhibits the strongest bioactivity, while key cannabinoids show high affinity for diabetes‐related targets, highlighting the plant as a promising source of novel antidiabetic ...
Rosa M. Chinheya   +6 more
wiley   +1 more source

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