Results 171 to 180 of about 18,081 (204)

Cannabidiol

Reactions Weekly, 2021
  +6 more sources

Cannabidiol and epilepsy

Cannabidiol (CBD) has been investigated as a pharmacological approach for treating a myriad of neurological and psychiatric disorders, the most successful of them being its use as an antiseizure drug (ASD). Indeed, CBD has reached the clinics for the treatment of certain epileptic syndromes. This chapter aims to overview the pharmacology of CBD and its
Fabrício A, Moreira, Antônio C P, de Oliveira, Victor R, Santos, Márcio F D, Moraes   +3 more
openaire   +2 more sources

Cannabidiol and pain

Chronic pain presents significant personal, psychological, and socioeconomic hurdles, impacting over 30% of adults worldwide and substantially contributing to disability. Unfortunately, current pharmacotherapy often proves inadequate, leaving fewer than 70% of patients with relief.
Nascimento, Glauce Crivelaro, Escobar-Espinal, Daniela, Bálico, Gabriela Gonçalves, Silva, Nicole Rodrigues, Del Bel, Elaine   +4 more
openaire   +3 more sources

Cannabidiol and addiction

Cannabidiol (CBD) has been investigated for several therapeutic applications, having reached the clinics for the treatment of certain types of epilepsies. This chapter reviews the potential of CBD for the treatment of substance use disorders (SUD). We will present a brief introduction on SUD and current treatments.
Rayssa C, Briânis, Fabrício A, Moreira, Lia P, Iglesias   +2 more
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Metabolism of cannabidiol by the rat

European Journal of Drug Metabolism and Pharmacokinetics, 1991
Metabolites of CBD excreted into the bile and perfusion fluid were examined in a rat liver perfusion preparation. Metabolites were extracted with ethyl acetate and identified by GC/MS as TMS derivatives. Four mono- and five di-hydroxy metabolites were identified with major sites of metabolic attack being at C-7 and C-4".
E, Samara, M, Bialer, D J, Harvey
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Cannabidiol

Reactions Weekly, 2018
  +5 more sources

Cannabidiol and cannabinol in man

Experientia, 1973
Le cannabidiol administre a dose de 100 mg par os et de 30 mg par injection i.v. fut inactif dans les sujets d'etude. Le cannabinol, a dose orale de 400 mg, le fut aussi. Ces constituants du cannabis ne contribuent donc pas a l'effet pharmacologique.
openaire   +2 more sources

Cannabidiol

Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry, 1977
P. G. Jones, L. Falvello, O. Kennard, G. M. Sheldrick, R. Mechoulam   +4 more
openaire   +1 more source

An overview on synthetic and biological activities of cannabidiol (CBD) and its derivatives

Bioorganic Chemistry, 2023
Bingyou Yang, Lixia Chen
exaly  

Cannabidiol as an antipsychotic drug

Cannabidiol (CBD) is a major phytocannabinoid in the Cannabis sativa plant. In contrast to Δ9-tetrahydrocannabinol (THC), CBD does not produce the typical psychotomimetic effects of the plant. In addition, CBD has attracted increased interest due to its potential therapeutic effects in various psychiatric disorders, including schizophrenia.
Débora, Fabris, João Roberto, Lisboa, Francisco Silveira, Guimarães, Felipe V, Gomes   +3 more
openaire   +2 more sources