Results 131 to 140 of about 91,153 (299)

Hippocampal subfield differences in people with and without recreational ketamine use: Insights from multi‐modal neuroimaging

open access: yesAddiction, EarlyView.
Abstract Background and aims Recreational ketamine use has increased globally and is associated with psychiatric and cognitive concerns. The hippocampus in preclinical models shows damage and working‐memory disruption with repeated dosing. However, whether specific hippocampal subregions may differ in people with chronic ketamine use remains unclear ...
Yi‐Hsuan Liu   +8 more
wiley   +1 more source

Cannabinoid‐Induced Hyperphagia is Mediated by Increased Meal Frequency and the Orexin‐1 Receptor in Male Rats

open access: yesPharmacology Research & Perspectives
Exogenous cannabinoids have long been known to promote eating. However, the underlying mechanisms have not been completely elucidated, which is critical to understanding their utility.
Magen N. Lord   +5 more
doaj   +1 more source

Cannabis-Containing Cream for CKD-Associated Pruritus: A Double-Blind, Placebo Controlled Trial

open access: yesKidney Medicine
Rationale & Objective: This study aims to compare the efficacy of a cannabis cream and a placebo in the treatment of chronic kidney disease (CKD)-associated pruritus. Study Design: A double-blind randomized controlled study.
Suthiya Anumas   +4 more
doaj   +1 more source

The prevalence of cannabidiol (CBD) use in North America and Europe: A meta‐analysis

open access: yesAddiction, EarlyView.
Abstract Background and aims The global cannabidiol (CBD) market has expanded in recent years. Several studies suggest CBD use, whether for medical or recreational purposes, is on the rise; however, no systematic assessments of its prevalence have been conducted so far. This meta‐analysis aimed to estimate the prevalence of CBD use in North America and
Sara Weidberg   +4 more
wiley   +1 more source

The endocannabinoid system as a therapeutic target in intestinal fibrosis

open access: yesFrontiers in Pharmacology
Intestinal fibrosis is a common and serious complication of inflammatory bowel diseases, often leading to strictures that require endoscopic or surgical intervention.
Zofia Misztal   +4 more
doaj   +1 more source

Temporal and geographical patterns of nitazene detections in drug samples and biospecimens in the United States, 2019–2024

open access: yesAddiction, EarlyView.
Abstract Background and aims Nitazenes are a novel subclass of synthetic opioids that have been increasingly implicated in the United States (US) overdose crisis. Despite their growing presence in the illicit drug supply, national trends have not been systematically evaluated.
David T. Zhu   +3 more
wiley   +1 more source

Negative symptoms as key features of depression among cannabis users: a preliminary report. [PDF]

open access: yes, 2016
OBJECTIVE: Cannabis use is frequent among depressed patients and may lead to the so-called "amotivational syndrome", which combines symptoms of affective flattening and loss of emotional reactivity (i.e. the so-called "negative" symptomatology). The aim
Albano, G   +9 more
core  

Determining the impact of cannabis use on tobacco cessation: Results from a prospective non‐randomized tobacco treatment trial

open access: yesAddiction, EarlyView.
Abstract Background and aims Tobacco‐cannabis co‐use is associated with increased psychosocial and health harms; however, the treatment literature assessing the impact of co‐use has been mixed and suffers from critical limitations. To date, no prospective studies have evaluated the degree to which cannabis co‐use affects tobacco cessation, nor are ...
Erin A. McClure   +6 more
wiley   +1 more source

In Search of the Neurobiological Substrates for Social Playfulness in Mammalian Brains

open access: yes, 2011
Play behavior is a fundamental and intrinsic neurobehavioral process in the mammalian brain. Using rough-and-tumble play in the juvenile rat as a model system to study mammalian playfulness, some of the relevant neurobiological substrates for this ...
Panksepp, Jaak, Siviy, Stephen M.
core   +1 more source

Brief report: Meth, tranq, gas station heroin & other drugs complicating addiction treatment

open access: yesThe American Journal on Addictions, EarlyView.
Abstract Background and Objectives Patients using fentanyl have worse treatment outcomes; however, little is known about other drugs that complicate treatment. Methods A national survey (n = 396) was conducted using a random sample of clinicians waivered to prescribe buprenorphine in the United States.
Erin L. Winstanley   +5 more
wiley   +1 more source

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