Results 121 to 130 of about 59,439 (317)

Design and synthesis of Heterocyclic Compounds as CB2 Selective Agoists

open access: yes, 2008
Cannabinoids are present in Indian hemp, Cannabis sativa L., and have been used since antiquity as medicinal agents(1). Interest in cannabinoid pharmacology has rapidly increased since the discovery of the endocannabinoid system (ECS), which includes ...
BENETTI, VERONICA
core  

The prevalence of cannabidiol (CBD) use in North America and Europe: A meta‐analysis

open access: yesAddiction, EarlyView.
Abstract Background and aims The global cannabidiol (CBD) market has expanded in recent years. Several studies suggest CBD use, whether for medical or recreational purposes, is on the rise; however, no systematic assessments of its prevalence have been conducted so far. This meta‐analysis aimed to estimate the prevalence of CBD use in North America and
Sara Weidberg   +4 more
wiley   +1 more source

Receptorial and pharmacological characterization of the new cannabinoid agonist NESS040C5

open access: yes, 2009
A number of studies indicate that cannabinoids can reduce intraocular pressure (IOP) both in animals and humans, suggesting a putative efficacy of these compounds in the treatment of glaucoma. Among the cannabinoid derivatives encompassed by Patent US 7,
Marcello S   +8 more
core  

Affinity and Efficacy Studies of Tetrahydrocannabinolic Acid A at Cannabinoid Receptor Types One and Two

open access: yes, 2017
Introduction: Cannabis biosynthesizes Δ9-tetrahydrocannabinolic acid (THCA-A), which decarboxylates into Δ9-tetrahydrocannabinol (THC). There is growing interest in the therapeutic use of THCA-A, but its clinical application may be hampered by ...
Phillip S. Grant   +11 more
core   +1 more source

Associations of cannabis use, tobacco use and co‐use with brain volume: A systematic review and meta‐analysis

open access: yesAddiction, EarlyView.
Abstract Background and aims Cannabis is the most widely used illicit drug worldwide and is often co‐used with tobacco, the leading cause of preventable death. Although cannabis and tobacco have distinct neurobiological actions, their associations with brain volumes are unclear.
Katherine Sawyer   +16 more
wiley   +1 more source

Medical cannabinoids [PDF]

open access: yesCanadian Medical Association Journal, 2017
Scott A, McLeod, Jean-François, Lemay
openaire   +5 more sources

Efficacy of Cannabis Oil in Improving Subjective Sleep Quality in Systemic Sclerosis: A Prospective Placebo-Controlled Study

open access: yesLife
Objective: We aimed to investigate the efficacy of cannabis oil in improving sleep quality, as evaluated using the Pittsburgh Sleep Quality Index (PSQI), in patients with systemic sclerosis (SSc) compared to placebo.
Apichart So-ngern   +7 more
doaj   +1 more source

Cannabinoid hyperemesis syndrome with extreme hydrophilia

open access: yes, 2013
Hilary A Enuh,1 Julia Chin,1 Jay Nfonoyim21Department of Medicine, 2Critical Care Unit, Richmond University Medical Center, Staten Island, NY, USAAbstract: Marijuana is the most widely used recreational drug in the US. Hyperemetic hydrophilic syndrome is
Nfonoyim J, Chin J, Enuh HA
core  

Highly Selective, Amine-Derived Cannabinoid Receptor 2 Probes

open access: yes, 2019
The endocannabinoid (eCB) system is implied in various human diseases ranging from central nervous system to autoimmune disorders. Cannabinoid receptor 2 (CB2R) is an integral component of the eCB system.
Christoph, Ullmer   +7 more
core   +1 more source

Temporal and geographical patterns of nitazene detections in drug samples and biospecimens in the United States, 2019–2024

open access: yesAddiction, EarlyView.
Abstract Background and aims Nitazenes are a novel subclass of synthetic opioids that have been increasingly implicated in the United States (US) overdose crisis. Despite their growing presence in the illicit drug supply, national trends have not been systematically evaluated.
David T. Zhu   +3 more
wiley   +1 more source

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