Results 101 to 110 of about 59,439 (317)

Cannabinoids [PDF]

open access: yesJournal of Pain and Symptom Management, 2013
Paul, Howard   +4 more
openaire   +2 more sources

Disrupted endocannabinoid signaling contributes to systemic inflammation in acute pancreatitis

open access: yesThe Journal of Pathology, EarlyView.
Abstract Acute pancreatitis (AP) is an inflammatory disease that can lead to systemic complications in severe cases. The endocannabinoid system has emerged as a potential modulator of inflammation in AP. We investigated the role of the endocannabinoid 2‐arachidonoylglycerol (2‐AG) and the cannabinoid receptors CB1 and CB2 during AP.
Paula Goncalves‐Romeu   +7 more
wiley   +1 more source

Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting

open access: yesPM&R, EarlyView.
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy   +3 more
wiley   +1 more source

Serum contents of endocannabinoids are correlated with blood pressure in depressed women.

open access: yes, 2012
BACKGROUND: Depression is known to be a risk factor for cardiovascular diseases but the underlying mechanisms remain unclear. Since recent preclinical evidence suggests that endogenous agonists of cannabinoid receptors (endocannabinoids) are involved in ...
Ho, WS V   +24 more
core   +1 more source

Intravenous paracetamol does not have significant opioid‐sparing effects when used as part of a multimodal analgesic protocol in dogs undergoing elective orthopaedic surgery

open access: yesVeterinary Record, EarlyView.
Abstract Background Data evaluating paracetamol combined with NSAIDs in dogs are scarce. Results of clinical studies in dogs investigating intravenous paracetamol vary. Methods Dogs were randomised to either receive 10 mg/kg paracetamol intravenously after induction of anaesthesia and every 8 hours during hospitalisation (test) or not (control).
Robin Stallard   +2 more
wiley   +1 more source

Enhanced self-administration of the CB1 receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms

open access: yesFrontiers in Pharmacology, 2014
Depression has been associated with drug consumption, including heavy or problematic cannabis use. According to an animal model of depression and substance use disorder comorbidity, we combined the olfactory bulbectomy model of depression with ...
Petra eAmchova   +19 more
doaj   +1 more source

Pharmacology of Cannabinoid

open access: yes, 2023
Cannabinoids are a group of chemical compounds found in the cannabid plant, with delta-9-tetrahydrocannabinol and cannabidiol being the most well-known compounds.
Park, Sujin
core  

Cannabinoids and haemostasis

open access: yesPostępy Higieny i Medycyny Doświadczalnej, 2016
Elements of the endocannabinoid system (cannabinoid receptors CB1, CB2, CBPT and CBED, endocannabinoids, enzymes involved in the synthesis and metabolism of endocannabinoids) are located on the structures involved in the process of hemostasis. An increasing level of endocannabinoids was also observed in some pathological conditions, which may occur in ...
Agnieszka, Zakrzeska   +3 more
openaire   +2 more sources

Insights from a six‐year hair drug analysis compendium in drug‐facilitated crimes involving vulnerable population cases

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Hair analysis is a well‐established matrix in forensic toxicology, offering a valuable alternative or complement to traditional matrices in diverse contexts, including drug‐facilitated crimes (DFC), elder abuse, and accidental exposure in children.
Amandine Fort   +8 more
wiley   +1 more source

Anxiolytic Effects of Repeated Cannabidiol Treatment in Teenagers With Social Anxiety Disorders

open access: yesFrontiers in Psychology, 2019
Accumulated evidence indicates that cannabidiol (CBD), a nonpsychotomimetic and nonaddictive main component of the Cannabis sativa plant, reverses anxiety-like behavior.
Nobuo Masataka
doaj   +1 more source

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