Results 251 to 260 of about 152,484 (372)

Deceptive beauty of non‐natural structures

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Structures of proteins and multiprotein complexes are considered landmark achievements. However, in many cases, mutant proteins are used for structural work. Even when wild type proteins are used, crystallization or complex formation for cryoEM is performed in highly nonphysiological conditions.
Vsevolod V. Gurevich   +1 more
wiley   +1 more source

The art of tolerance [PDF]

open access: yes, 1998
M Terakura   +12 more
core   +1 more source

Changing trends in drug overdose mortality in Spain, 2001–2022

open access: yesAddiction, Volume 121, Issue 2, Page 261-272, February 2026.
Abstract Aim To measure the evolution of drug overdose mortality in Spain between 2001 and 2022. Design, Setting, Participants A repeated cross‐sectional observational study using nationwide mortality data from Spain, 2001–2022, among individuals aged 15–64 years.
Florencia Giné   +6 more
wiley   +1 more source

Cannabidiol in autism: Clinical pharmacology priorities for trial design

open access: yes
British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 357-359, February 2026.
Gislei Frota Aragão   +2 more
wiley   +1 more source

Antiseizure Effects of Cannabidiol in Combination With Cannabigerol in the Maximal Electroshock Seizure Model

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 2, February 2026.
Cannabidiol and cannabigerol suppress maximal electroshock seizures. Cannabidiol and cannabigerol show similar dose–response properties. Both cannabinoids show no toxicity at effective doses. ABSTRACT Current antiseizure therapy for epilepsy is only effective in about 70% of the patient population.
Han Zhong Zhou   +3 more
wiley   +1 more source

Pharmacotherapy for Cannabis Use Disorder: Preclinical and Clinical Models. [PDF]

open access: yesCurr Top Behav Neurosci
Bedillion MF   +5 more
europepmc   +1 more source

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