Results 321 to 330 of about 152,484 (372)
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Glucose metabolism links astroglial mitochondria to cannabinoid effects
Nature, 2020Daniel Jiménez-Blasco +2 more
exaly +2 more sources
International Journal of Molecular Sciences, 2018 The biological effects of cannabinoids, the major constituents of the ancient medicinal plant Cannabis sativa (marijuana) are mediated by two members of the G-protein coupled receptor family, cannabinoid receptors 1 (CB1R) and 2.
Ujendra Kumar
exaly +2 more sources
An Introduction to the Endogenous Cannabinoid System
Biological Psychiatry, 2016 Ken Mackie
exaly +2 more sources
The endogenous cannabinoid system controls extinction of aversive memories
Nature, 2002Giovanni Marsicano +2 more
exaly +2 more sources
Cannabinoid Interactions with Cytochrome P450 Drug Metabolism: a Full-Spectrum Characterization
AAPS Journal, 2021Medicinal cannabis use has increased exponentially with widespread legalization around the world. Cannabis-based products are being used for numerous health conditions, often in conjunction with prescribed medications.
P. Doohan +3 more
semanticscholar +1 more source
Cannabinoids, cannabinoid receptors and tinnitus
Hearing Research, 2016One hypothesis suggests that tinnitus is a form of sensory epilepsy, arising partly from neuronal hyperactivity in auditory regions of the brain such as the cochlear nucleus and inferior colliculus. Although there is currently no effective drug treatment for tinnitus, anti-epileptic drugs are used in some cases as a potential treatment option. There is
Paul F, Smith, Yiwen, Zheng
openaire +2 more sources
Life Sciences, 2006
After their discovery, the two known cannabinoid receptors, CB(1) and CB(2), have been the focus of research into the cellular signalling mechanisms of cannabinoids. The initial assessment, mainly derived from expression studies, was that cannabinoids, via G(i/o) proteins, negatively modulate cyclic AMP levels, and activate inward rectifying K ...
Dirk G, Demuth, Areles, Molleman
openaire +2 more sources
After their discovery, the two known cannabinoid receptors, CB(1) and CB(2), have been the focus of research into the cellular signalling mechanisms of cannabinoids. The initial assessment, mainly derived from expression studies, was that cannabinoids, via G(i/o) proteins, negatively modulate cyclic AMP levels, and activate inward rectifying K ...
Dirk G, Demuth, Areles, Molleman
openaire +2 more sources
Current Drug Target -CNS & Neurological Disorders, 2005
Since the discovery of an endogenous cannabinoid system, research into the pharmacology and therapeutic potential of cannabinoids has steadily increased. Two subtypes of G-protein coupled cannabinoid receptors, CB(1) and CB(1), have been cloned and several putative endogenous ligands (endocannabinoids) have been detected during the past 15 years.
openaire +4 more sources
Since the discovery of an endogenous cannabinoid system, research into the pharmacology and therapeutic potential of cannabinoids has steadily increased. Two subtypes of G-protein coupled cannabinoid receptors, CB(1) and CB(1), have been cloned and several putative endogenous ligands (endocannabinoids) have been detected during the past 15 years.
openaire +4 more sources
Pharmacology & Therapeutics, 2002
During the last decade, rigorous scientific methods have been applied to determine the effects of cannabinoids on nociceptive neurotransmission. Cannabinoids have been observed to markedly decrease signalling in specific neural pathways that transmit messages about pain.
J Michael, Walker, Susan M, Huang
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During the last decade, rigorous scientific methods have been applied to determine the effects of cannabinoids on nociceptive neurotransmission. Cannabinoids have been observed to markedly decrease signalling in specific neural pathways that transmit messages about pain.
J Michael, Walker, Susan M, Huang
openaire +2 more sources
The American Journal of the Medical Sciences, 2015
Synthetic cannabinoids (SCBs), also known under the brand names of "Spice," "K2," "herbal incense," "Cloud 9," "Mojo" and many others, are becoming a large public health concern due not only to their increasing use but also to their unpredictable toxicity and abuse potential.
Brooke, Mills +2 more
openaire +2 more sources
Synthetic cannabinoids (SCBs), also known under the brand names of "Spice," "K2," "herbal incense," "Cloud 9," "Mojo" and many others, are becoming a large public health concern due not only to their increasing use but also to their unpredictable toxicity and abuse potential.
Brooke, Mills +2 more
openaire +2 more sources