Results 111 to 120 of about 41,551 (306)
Addiction, EarlyView.Abstract Background and aims Nitazenes are a novel subclass of synthetic opioids that have been increasingly implicated in the United States (US) overdose crisis. Despite their growing presence in the illicit drug supply, national trends have not been systematically evaluated.
David T. Zhu +3 more
wiley +1 more source
O antagonista canabinóide SR141716A facilita a consolidação da memória no labirinto em "T" elevado [PDF]
, 2002 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Farmacologia.Os efeitos do antagonista do receptor canabinóide CB1, SR141716A, nos processos de aprendizado e memória foram ...
Fernandes, Marcelo Soares
core
, 2020 Cannabinoid receptor 2 (CB2) is a promising target for the treatment of neuroinflammation and other diseases. Howev-er, lack of understanding of its complex signaling in cells and tissues complicates its therapeutic targeting.
James, Frank +7 more
core +1 more source
Addiction, EarlyView.Abstract Background and aims Tobacco‐cannabis co‐use is associated with increased psychosocial and health harms; however, the treatment literature assessing the impact of co‐use has been mixed and suffers from critical limitations. To date, no prospective studies have evaluated the degree to which cannabis co‐use affects tobacco cessation, nor are ...
Erin A. McClure +6 more
wiley +1 more source
Biochemistry of the Endogenous Ligands of Cannabinoid Receptors
Neurobiology of Disease, 1998 In 1992 the discovery of the first endogenous ligand of cannabinoid receptors, anandamide, provided conclusive support to the hypothesis that an “endogenous cannabinoid regulatory system” exists in mammalian nervous tissue.
Vincenzo Di Marzo, Dale G. Deutsch
doaj +1 more source
Design and synthesis of Heterocyclic Compounds as CB2 Selective Agoists
, 2008 Cannabinoids are present in Indian hemp, Cannabis sativa L., and have been used since antiquity as medicinal agents(1). Interest in cannabinoid pharmacology has rapidly increased since the discovery of the endocannabinoid system (ECS), which includes ...
BENETTI, VERONICA
core
Addiction, EarlyView.Abstract Aim Our primary aim was to conduct a network meta‐analysis (NMA) for the effectiveness, safety and acceptability of all psychosocial interventions and all pharmacotherapies for cannabis use disorder (CUD). Methods We conducted a NMA of studies identified from two completed systematic reviews examining the effectiveness, safety and ...
Monika Halicka +6 more
wiley +1 more source
, 2007 Endocannabinoids are lipid signaling mediators that exert an important neuromodulatory role and confer neuroprotection in several types of brain injury.
Monory, Krisztina +8 more
core +1 more source
The association between sleep disturbance and stimulant use: A cross‐lagged examination
Addiction, EarlyView.Abstract Background and aims Sleep disruptions increase the risk of substance misuse. Substance use—especially stimulants—can increase acute and chronic sleep dysfunction. This study aimed to estimate the associations between sleep disturbance and stimulant use over time among participants with stimulant use disorder (StUD).
Viviana E. Horigian +12 more
wiley +1 more source
Edible cannabinoids impact meal structure and food impulsivity in female rats
iScienceSummary: Cannabinoid receptor agonists increase eating in a dose-dependent manner. However, the behavioral mechanisms by which cannabinoids modulate food intake control aren’t clear, particularly in females.
Magen N. Lord +4 more
doaj +1 more source