Results 61 to 70 of about 2,668,334 (282)

Occurrence of Takotsubo Cardiomyopathy after Synthetic Cannabinoid Consumption [PDF]

Addiction and Health, 2019
Background: Synthetic cannabinoid use such as “K2” and “Spice” is popular secondary to its inability to be detected in a urine drug screen. It is associated with a wide range of myocardial pathologies including obstructive and non-obstructive coronary ...
Denelle Mohammed
doaj   +1 more source

The endocannabinoid system regulates both ependymoglial and neuronal cell responses to a tail amputation in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the endocannabinoid system in the regeneration of the tail and spinal ...
Michael Tolentino, Sarah E. Walker, Gaynor E. Spencer, Robert Carlone   +3 more
wiley   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Cannabinoids: A New Group of Agonists of PPARs

PPAR Research, 2007
Cannabinoids have been used medicinally and recreationally for thousands of years and their effects were proposed to occur mainly via activation of the G-protein-coupled receptor CB1/CB2 (cannabinoid receptor 1/2).
Yan Sun, Andy Bennett
doaj   +1 more source

Differentiating Nonsuicidal Self‐Injury (NSSI) From Suicide Attempts in Adolescents: A Pilot Study

Medicine Bulletin, EarlyView.
ABSTRACT Background Differentiating between nonsuicidal self‐injury (NSSI) and suicide attempts (SA) in adolescents is crucial due to distinct underlying motivations, treatment needs, and potential outcomes associated with each behavior.
María Posada‐Ayala, Ping Wang, Gemma Barroso‐Garcia, Encarnación Donoso‐Navarro, Elena Hernandez‐Alvarez, María Gil‐Ligero, Julián Romero, Silvia Rosado‐Garcia, Antonio José Sánchez‐López, Hilario Blasco‐Fontecilla   +9 more
wiley   +1 more source

Involvement of cannabinoid receptors in depression of the putative nociceptive response in spinal cord preparations isolated from neonatal rats

Journal of Physiological Sciences, 2023
A metabolite of acetaminophen, AM404, which is an anandamide transporter inhibitor, induces analgesia mainly via activation of transient receptor potential channel 1 in the spinal cord, although the role of cannabinoid receptors remains to be studied ...
Kayo Tsuzawa, Hiroshi Onimaru, Katsunori Inagaki, Masahiko Izumizaki   +3 more
doaj   +1 more source

Long‐Term Follow‐Up of Patients with Mass Social Media‐Induced Illness Presenting with Functional Tic‐like Behaviors

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Only little is known about the prognosis of functional tic‐like behaviors (FTLB), especially in the subgroup of patients with mass social media‐induced illness (MSMI‐FTLB). Objectives To provide data of long‐term follow‐up (FU) of a carefully characterized group of patients with MSMI‐FTLB to identify influencing factors such as ...
L. Kathrin Hartung, Simon Schmitt, Carolin Fremer, Carolin S. Klages, Natalia Szejko, Kirsten R. Müller‐Vahl   +5 more
wiley   +1 more source

Cannabinoid receptor type-1: breaking the dogmas [version 1; referees: 3 approved]

F1000Research, 2016
The endocannabinoid system (ECS) is abundantly expressed in the brain. This system regulates a plethora of physiological functions and is composed of cannabinoid receptors, their endogenous ligands (endocannabinoids), and the enzymes involved in the ...
Arnau Busquets Garcia, Edgar Soria-Gomez, Luigi Bellocchio, Giovanni Marsicano   +3 more
doaj   +1 more source

Type 2 Diabetes Alters Vascular Cannabinoid Receptor 1 Expression, Phosphorylation Status, and Vasorelaxation in Rat Aorta

Molecules, 2020
Previous studies have suggested a role of the endocannabinoid system in metabolic diseases, such as diabetes. We investigated the effect of diabetes on cannabinoid receptor type 1 (CB1) expression and cannabinoid-induced vasorelaxation in rat aorta rings.
Enrique Sánchez-Pastor, Xóchitl Trujillo, Christian Ramos-Flores, Mónica Ríos-Silva, Felipa Andrade, Yolitzy Cárdenas, Elena Castro, Zorayda Urzúa, Oscar Newton-Sánchez, Miguel Huerta   +9 more
doaj   +1 more source

Gray Matter Volume Loss in Parkinson's Disease Psychosis and Cannabinoid Receptor Gene Expression in the Brain

Movement Disorders, EarlyView.
Abstract Background Serotonergic and dopaminergic pathways are implicated in Parkinson's disease psychosis (PDP), but preliminary evidence also implicates the endocannabinoid system (ECS). Objectives We examined the association of gray matter volume loss in PDP patients with brain expression of the genes coding for CB1 (cannabinoid type 1) and CB2 ...
Sara Pisani, František Váša, Latha Velayudhan, Sagnik Bhattacharyya   +3 more
wiley   +1 more source