Results 151 to 160 of about 6,065 (241)

Clinical significance of exercise‐induced hypoalgesia in individuals with temporomandibular disorders and neck pain: A clinical trial protocol

Experimental Physiology, Volume 111, Issue 6, Page 2777-2786, 1 June 2026.
Abstract Evidence reports positive effects of neck motor control and aerobic exercises (AEs) to improve pain in individuals with temporomandibular disorders (TMD) and neck pain. A single bout of exercise typically leads to an increase in pain thresholds up to 30 min post‐exercise, known as exercise‐induced hypoalgesia (EIH).
Luiz Felipe Tavares, Ana Izabela Sobral de Oliveira‐Souza, Vladimir Aron, Ana Beatriz Oliveira, Henrik Bjarke Vaegter, Susan Armijo‐Olivo   +5 more
wiley   +1 more source

The effectiveness of aerobic exercise on pain and disability in individuals with neck pain: A systematic review and meta‐analysis

Experimental Physiology, Volume 111, Issue 6, Page 2918-2944, 1 June 2026.
Abstract The present review aimed to investigate the effectiveness of aerobic exercise (AE) compared to other interventions in decreasing pain intensity and reducing disability in individuals with neck pain. A systematic review (SR) of randomized controlled trials was conducted. This SR was registered in PROSPERO (CRD42021231231).
Ana lzabela Sobral de Oliveira‐Souza, Marie Kempe, Sofia Grimmelsmann, Luiz Felipe Tavares, Ester Moreira De Castro‐Carletti, Angela Viegas Andrade, Liz Dennett, Harry Von Piekartz, Jorge Fuentes Contreras, Susan Armijo‐Olivo   +9 more
wiley   +1 more source

Allosteric modulation of the cannabinoid receptors

, 2008
During this study the [35S]GTPγS binding, equilibrium binding and dissociation kinetic assays were utilised to investigate allosteric modulation of the cannabinoid receptors.
Baillie, Gemma
core  

The endogenous cannabinoid system gates plasticity of tonic GABA inhibition

The Journal of Physiology, Volume 604, Issue 12, Page 4984-5010, 15 June 2026.
Abstract figure legend Postsynaptic depolarisation and increases in intracellular Ca2+ ([Ca2+]i) trigger the synthesis of endocannabinoids (eCBs), which are hypothesised to enhance tonic GABAergic inhibition via two primary pathways. In the proposed autocrine mechanism, eCBs activate postsynaptic somatodendritic or mitochondrial CB1 receptors ...
Roberto Colangeli, Fiorenzo Conti
wiley   +1 more source

Acute metabolic effects of cannabinoid receptor modulators during sequential hyperglycemic, euglycemic-hyperinsulinemic clamps in healthy individuals. [PDF]

Am J Physiol Endocrinol Metab
Chia CW, Tang EY, Cutler RG, You SS, Chen Q, Choo AYM, Melvin DL, Ramsden CE, Kapogiannis D, Egan JM.   +9 more
europepmc   +1 more source

Precision phenotyping of elevated arousal in posttraumatic stress disorder: implications for personalized GABAergic pharmacotherapy. [PDF]

Front Psychiatry
Vasquez VR, Howlett JR.
europepmc   +1 more source

Biochemische und funktionelle Charakterisierung zellfrei exprimierter G-Protein-gekoppelter Rezeptoren des humanen Endothelin-Systems

, 2011
G-protein coupled receptors (GPCRs) are the key players in signal perception and transduction and one of the currently most important class of drug targets.
Junge, Friederike Alessandra
core  

Cannabinoids in Alzheimer's disease: animal-human evidence and clinical pharmacology challenges. [PDF]

Front Behav Neurosci
Komedera M, Wojda U, Kiryk A.
europepmc   +1 more source

Genetically Encoded CB₂R-Based Fluorescent Sensor Enables Rapid Screening and Functional Assessment of Cannabinoid Modulators. [PDF]

Int J Mol Sci
Bhattacharjee P, Volesky PD, Shivshankar S, Puhl H, Iyer MR.   +4 more
europepmc   +1 more source

Targeting Pain and Depression in Alzheimer's Disease: Translational Insights and Emerging Treatments. [PDF]

Pharmaceuticals (Basel)
Costachescu I, Stanciu GD, Gogu RM, Tamba BI.   +3 more
europepmc   +1 more source