Results 41 to 50 of about 56,803 (285)
Interactions of the opioid and cannabinoid systems in reward: Insights from knockout studies
Frontiers in Pharmacology, 2015 The opioid system consists of three receptors, mu, delta, and kappa, which are activated by endogenous opioid peptides (enkephalins, endorphins and dynorphins). The endogenous cannabinoid system comprises lipid neuromodulators (endocannabinoids), enzymes
Katia eBefort
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Mechanical and material properties of cortical and trabecular bone from cannabinoid receptor-1-null (Cnr1-/-) mice [PDF]
, 2016 Funding ABK was funded by a studentship from the University of Aberdeen, Institute of Medical Sciences, and the Overseas Research Students Awards Scheme Acknowledgments We are grateful to Dr J.S. Gregory for assistance with Image J and Mr K.
Aspden, Richard M +3 more
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Cannabinoids reduce markers of inflammation and fibrosis in pancreatic stellate cells.
PLoS ONE, 2008 BackgroundWhile cannabinoids have been shown to ameliorate liver fibrosis, their effects in chronic pancreatitis and on pancreatic stellate cells (PSC) are unknown.Methodology/principal findingsThe activity of the endocannabinoid system was evaluated in ...
Christoph W Michalski +10 more
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The Impact of CB1 Receptor on Inflammation in Skeletal Muscle Cells
Journal of Inflammation Research, 2021 Mansour Haddad Faculty of Pharmacy, Philadelphia University, Amman, JordanCorrespondence: Mansour Haddad Email Dr.man.haddad@gmail.comBackground: Various factors trigger the inflammatory response and cytokine activation in skeletal muscle.
Haddad M
doaj
Cannabinoid type 1 receptors transiently silence glutamatergic nerve terminals of cultured cerebellar granule cells. [PDF]
PLoS ONE, 2014 Cannabinoid receptors are the most abundant G protein-coupled receptors in the brain and they mediate retrograde short-term inhibition of neurotransmitter release, as well as long-term depression of synaptic transmission at many excitatory synapses.
Jorge Ramírez-Franco +4 more
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Cannabinoid Signaling in Auditory Function and Development
Frontiers in Molecular Neuroscience, 2021 Plants of the genus Cannabis have been used by humans for millennia for a variety of purposes. Perhaps most notable is the use of certain Cannabis strains for their psychoactive effects.
Sumana Ghosh +3 more
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Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s) [PDF]
, 2015 ACKNOWLEDGMENTS The work was supported by National Institutes of Health grants DA027113 and EY024717 to G.A.T. and DA09158 to A.M. A portion of this work was submitted in 2011 by A. Kulkarni in partial fulfillment of M.S.
Cascio, Maria G. +12 more
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Advanced Healthcare Materials, EarlyView.Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram +10 more
wiley +1 more source
Pharmacology Research & PerspectivesThe co‐expression of different types of G protein‐coupled receptors (GPCRs) in the same cells can have implications for receptor signaling and receptor cross‐talk, potentially altering the apparent potency or efficacy of ligands targeting each receptor ...
Kawthar A. Mohamed, Robert B. Laprairie
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Dendritic Cell Regulation by Cannabinoid-Based Drugs
Pharmaceuticals, 2010 Cannabinoid pharmacology has made important advances in recent years after the cannabinoid system was discovered. Studies in experimental models and in humans have produced promising results using cannabinoid-based drugs for the treatment of obesity and ...
Mattias Svensson +2 more
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