Results 91 to 100 of about 123,443 (349)

Cannabinoids—Multifunctional Compounds, Applications and Challenges—Mini Review

Molecules
Cannabinoids represent a highly researched group of plant-derived ingredients. The substantial investment of funds from state and commercial sources has facilitated a significant increase in knowledge about these ingredients.
Dominik Duczmal, Aleksandra Bazan-Wozniak, Krystyna Niedzielska, Robert Pietrzak   +3 more
doaj   +1 more source

Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies

Pain, 2018
This review examines evidence for the effectiveness of cannabinoids in chronic noncancer pain (CNCP) and addresses gaps in the literature by: considering differences in outcomes based on cannabinoid type and specific CNCP condition; including all study ...
E. Stockings, G. Campbell, W. Hall, S. Nielsen, Dino Zagic, R. Rahman, B. Murnion, M. Farrell, Megan Weier, L. Degenhardt   +9 more
semanticscholar   +1 more source

The potential role of cannabinoids in dermatology

Journal of dermatological treatment (Print), 2020
Cannabis is increasingly being used world-wide to treat a variety of dermatological conditions. Medicinal cannabis is currently legalized in Canada, 31 states in America and 19 countries in Europe.
T. Sheriff, Matthew J Lin, D. Dubin, H. Khorasani   +3 more
semanticscholar   +1 more source

Milk Fat Globule Membrane Supplementation Attenuates Cognitive Impairment in APP/PS1 Mice via Suppressing Neuroinflammation in a Gut Microbiota‐Mediated Serum Resolvin D1/Anandamide Manner

Food Frontiers, EarlyView.
MFGM modulated gut microbiota accompanied by the increased serum RVD1 and AEA levels, which subsequently regulated the miRNA profile. This modulation alleviated neuroinflammation via suppressing the NLRP3 inflammasome signaling and microglial activation, thereby attenuating AD‐related cognitive impairment both in vivo and in vitro.
Han Gong, Qichen Yuan, Min Du, Xiaohan Liu, Xueying Mao   +4 more
wiley   +1 more source

Endocannabinoid system and anticancer properties of cannabinoids [PDF]

, 2016
Cannabinoids impact human body by binding to cannabinoids receptors (CB1 and CB2). The two main phytocannabinoids are Δ9-tetrahydrocannabinol (THC) and cannabidiol (CBD).
Nowak, Agnieszka, Słomski, Ryszard, Zeyland, Joanna, Śledziński, Paweł   +3 more
core   +1 more source

In-depth comparison of the metabolic and pharmacokinetic behaviour of the structurally related synthetic cannabinoids AMB-FUBINACA and AMB-CHMICA in rats

Communications Biology, 2022
Synthetic cannabinoids are amongst the most widely used psychoactive drugs which are tightly controlled by government agencies around the world. Here, pharmacokinetics of two synthetic cannabinoids in rats are evaluated along with their metabolites and ...
David Fabregat-Safont, María Mata-Pesquera, Manuela Barneo-Muñoz, Ferran Martinez-Garcia, Marie Mardal, Anders B. Davidsen, Juan V. Sancho, Félix Hernández, María Ibáñez   +8 more
doaj   +1 more source

Cannabinoids and Pain: New Insights From Old Molecules

Frontiers in Pharmacology, 2018
Cannabis has been used for medicinal purposes for thousands of years. The prohibition of cannabis in the middle of the 20th century has arrested cannabis research.
S. Vučković, D. Srebro, K. S. Vujović, Č. Vučetić, M. Prostran   +4 more
semanticscholar   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

A Case Report on Cannabinoid Hyperemesis Syndrome in Palliative Care: How Good Intentions Can Go Wrong [PDF]

, 2022
Helen Senderovich, Sarah Waicus
openalex   +1 more source

Cannabinoids in Chronic Non-Cancer Pain: A Systematic Review and Meta-Analysis

Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders, 2020
Background: For patients with chronic, non-cancer pain, traditional pain-relieving medications include opioids, which have shown benefits but are associated with increased risks of addiction and adverse effects.
H. Johal, T. Devji, Yaping Chang, Jonathan Simone, C. Vannabouathong, M. Bhandari   +5 more
semanticscholar   +1 more source