Results 131 to 140 of about 50,545 (304)

Cannabinoid receptors [PDF]

Current Biology, 2002
openaire   +2 more sources

Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor

, 2016
Thuy Nguyen, Jun‐Xu Li, Brian F. Thomas, Jenny L. Wiley, Terry Kenakin, Yanan Zhang   +5 more
openalex   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

GABA release at terminals of CCK‐interneurons: synchrony, asynchrony and modulation by cannabinoid receptors (Commentary on Ali & Todorova) [PDF]

, 2010
Péter Jónás, Stefan Hefft
openalex   +1 more source

Delta‐9‐Tetrahydrocannabinol (THC) Before Bedtime: Feasibility and Mechanistic Pilot Study on Sleep and Cardiac Autonomic Activity

Journal of Sleep Research, EarlyView.
ABSTRACT Disordered sleep is a common reason individuals report using cannabis, yet the physiological effects of Δ9‐tetrahydrocannabinol (Δ9‐THC) on sleep and autonomic regulation remain incompletely understood. Early studies reported acute sleep‐promoting effects of Δ9‐THC, but chronic use has been associated with disrupted sleep and possible ...
Joshua E. Gonzalez, Alicia V. Stewart, Jacquelin L. Ellison, Omar H. Ordaz, LaTroy D. Robinson, Noal A. Clemons, Jonathan S. Emens, Sean P. M. Rice, Steven A. Shea, Nicole P. Bowles   +9 more
wiley   +1 more source

Multifaceted roles of BBX transcription factors: impacts on key agronomical traits and environmental resilience

New Phytologist, EarlyView.
Summary B‐box (BBX) proteins were initially characterized as transcription factors connecting light signaling to the regulation of flowering time and seedling photomorphogenesis. However, over the last decade, increasing evidence has shown that they integrate light and hormone signaling, modulating multiple physiological processes during plant life. In
Bruno Silvestre Lira, Juliene Moreira, Luciano Freschi, Magdalena Rossi   +3 more
wiley   +1 more source

Resurrected Ancestral Cannabis Enzymes Unveil the Origin and Functional Evolution of Cannabinoid Synthases

Plant Biotechnology Journal, EarlyView.
ABSTRACT Cannabinoids, such as tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA) and cannabichromenic acid (CBCA), are bioactive and medicinally relevant compounds found in the cannabis plant (Cannabis sativa L.). These three compounds are synthesised from a single precursor, cannabigerolic acid (CBGA), through regioselective reactions ...
Cloé Villard, Idil Baser, Arjen C. van de Peppel, Katarina Cankar, M. Eric Schranz, Robin van Velzen   +5 more
wiley   +1 more source

Cannabinoid Therapies in Less-Common Disorders: Clinical Evidence and Formulation Strategies. [PDF]

Diseases
Afonso S, Gonçalves J, Brinca AT, Rosendo LM, Rosado T, Duarte AP, Gallardo E.   +6 more
europepmc   +1 more source

Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ⁹‐tetrahydrocannabinol in BV‐2 microglial cells [PDF]

, 2011
Ana Juknat, Maciej Pietr, Ewa Kozela, Neta Rimmerman, Rivka Levy, Giovanni Coppola, Daniel H. Geschwind, Zvi Vogel   +7 more
openalex   +1 more source