Results 131 to 140 of about 122,153 (397)
On the G-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulation [PDF]
, 2013 The modulatory role of allosteric receptor-receptor interactions in the pain pathways of the Central Nervous System and the peripheral nociceptors has become of increasing interest.
Agnati, Luigi F +6 more
core +3 more sources
Food Frontiers, EarlyView.MFGM modulated gut microbiota accompanied by the increased serum RVD1 and AEA levels, which subsequently regulated the miRNA profile. This modulation alleviated neuroinflammation via suppressing the NLRP3 inflammasome signaling and microglial activation, thereby attenuating AD‐related cognitive impairment both in vivo and in vitro.
Han Gong +4 more
wiley +1 more source
Analgesic Effects of Fatty Acid Amide Hydrolase Inhibition in a Rat Model of Neuropathic Pain [PDF]
, 2006 Cannabinoid-based medicines have therapeutic potential for the treatment of pain. Augmentation of levels of endocannabinoids with inhibitors of fatty acid amide hydrolase (FAAH) is analgesic in models of acute and inflammatory pain states.
Barrett, David +4 more
core +2 more sources
Ibrain, EarlyView.Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley +1 more source
Altered glial expression of the cannabinoid 1 receptor in the subiculum of a mouse model of Alzheimer's disease [PDF]
, 2022 Itziar Terradillos +14 more
openalex +1 more source
Biological Psychiatry, 2014 Signs posted in coffee shops throughout California warn their readers that “chemicals known to cause cancer and reproductive toxicity are present in coffee, baked goods and other foods or beverages sold here.” Undeterred by the admonition, every day millions of Californians eat their morning muffin accompanied by a hefty coffee drink.
openaire +4 more sources
Cannabis shenanigans: advocating for the restoration of an effective treatment of pain following spinal cord injury. [PDF]
, 2018 Cannabis is an effective treatment for pain following spinal cord injury that should be available to patients and researchers. The major argument against the rescheduling of cannabis is that the published research is not convincing.
Graves, PhD, Daniel E.
core +1 more source
Cannabinoid Receptor Involvement in Stress-Induced Cocaine Reinstatement: Potential Interaction with Noradrenergic Pathways [PDF]
, 2012 This study examined the role of endocannabinoid signaling in stress-induced reinstatement of cocaine seeking and explored the interaction between noradrenergic and endocannabinergic systems in the process.
Hillard, Cecilia J. +6 more
core +2 more sources
Cannabinoids, Endocannabinoids and Sleep
Frontiers in Molecular Neuroscience, 2020 Sleep is a vital function of the nervous system that contributes to brain and bodily homeostasis, energy levels, cognitive ability, and other key functions of a variety of organisms. Dysfunctional sleep induces neural problems and is a key part of almost
Andrew J. Kesner, D. Lovinger
semanticscholar +1 more source
Cold EI—The Way to Improve GC‐MS and Increase Its Range of Applications
Mass Spectrometry Reviews, EarlyView.ABSTRACT Gas chromatography‐mass spectrometry (GC‐MS) with Cold electron ionization (EI) is based on interfacing the GC and MS with a supersonic molecular beam (SMB) along with electron ionization of vibrationally cold sample compounds in the SMB in a contact‐free fly‐through ion source (hence the name Cold EI).
Aviv Amirav +3 more
wiley +1 more source