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Cannabinoids and the eye

Survey of Ophthalmology, 2021
Cannabis ranks among the most commonly used psychotropic drugs worldwide. In the context of the global movement toward more widespread legalisation, there is a growing need toward developing a better understanding of the physiological and pathological effects. We provide an overview of the current evidence on the effects of cannabinoids on the eye.
Michael T.M. Wang, Helen V. Danesh-Meyer
openaire   +2 more sources

Cannabinoids and Anxiety

2009
The term cannabinoids encompasses compounds produced by the plant Cannabis sativa, such as delta9-tetrahydrocannabinol, and synthetic counterparts. Their actions occur mainly through activation of cannabinoid type 1 (CB1) receptors. Arachidonoyl ethanolamide (anandamide) and 2-arachidonoyl glycerol (2-AG) serve as major endogenous ligands ...
Moreira, F., Wotjak, C.
openaire   +3 more sources

Cannabinoid signalling

Life Sciences, 2006
After their discovery, the two known cannabinoid receptors, CB(1) and CB(2), have been the focus of research into the cellular signalling mechanisms of cannabinoids. The initial assessment, mainly derived from expression studies, was that cannabinoids, via G(i/o) proteins, negatively modulate cyclic AMP levels, and activate inward rectifying K ...
Dirk G, Demuth, Areles, Molleman
openaire   +2 more sources

The cannabinoid receptors

Prostaglandins & Other Lipid Mediators, 2002
Cannabinoid receptors were named because they have affinity for the agonist delta9-tetrahydrocannabinol (delta9-THC), a ligand found in organic extracts from Cannabis sativa. The two types of cannabinoid receptors, CB1 and CB2. are G protein coupled receptors that are coupled through the Gi/o family of proteins to signal transduction mechanisms that ...
openaire   +2 more sources

Cannabinoids and Neuroprotection

Molecular Neurobiology, 2001
Cannabinoid compounds are endowed with pharmacological properties that make them interesting candidates for therapeutic development. These properties have been known since antiquity. However, in the last decade extremely important advances in the understanding of the physiology, pharmacology, and molecular biology of the cannabinoid system have given ...
Grundy, Robert   +2 more
openaire   +3 more sources

The pyrolysis of cannabinoids

1987
Plants of the genus Cannabis are known to produce stronger and more immediate effects when smoked, the usual way of administration in Western countries, than when orally taken in similar amounts. In particular, the psychoactive effects are stronger than could be expected from the initial tetrahydrocannabinol (THC) content (Galanter et al.
openaire   +2 more sources

Biosynthesis of cannabinoids and cannabinoid precursors

2021
ANDERSON KIM CECELIA   +8 more
  +12 more sources

Cannabinoids, Phenolics, Terpenes and Alkaloids of Cannabis

Molecules, 2021
Mahmoud Elsohly   +2 more
exaly  

Cannabinoids

British Journal of Hospital Medicine, 2016
openaire   +2 more sources

Cannabinoids and Psychosis

2007
Recent epidemiological studies and advances in understanding of brain cannabinoid function have renewed interest in the long-recognized association between cannabinoids and psychosis. This chapter presents evidence supporting and refuting the association between cannabinoids and psychosis.
openaire   +2 more sources

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