Results 21 to 30 of about 240,123 (312)

Modulation of type 1 cannabinoid receptor activity by cannabinoid by-products from Cannabis sativa and non-cannabis phytomolecules

Frontiers in Pharmacology, 2022
Cannabis sativa contains more than 120 cannabinoids and 400 terpene compounds (i.e., phytomolecules) present in varying amounts. Cannabis is increasingly available for legal medicinal and non-medicinal use globally, and with increased access comes the ...
Ayat Zagzoog, Ashley Cabecinha, Hanan Abramovici, Robert B. Laprairie, Robert B. Laprairie   +4 more
doaj   +1 more source

Effects of oral, smoked, and vaporized cannabis on endocrine pathways related to appetite and metabolism: a randomized, double-blind, placebo-controlled, human laboratory study. [PDF]

, 2020
As perspectives on cannabis continue to shift, understanding the physiological and behavioral effects of cannabis use is of paramount importance. Previous data suggest that cannabis use influences food intake, appetite, and metabolism, yet human research
Abulseoud, Osama A, Farokhnia, Mehdi, Huestis, Marilyn A, Leggio, Lorenzo, McDiarmid, Gray R, Munjal, Vikas, Newmeyer, Matthew N   +6 more
core   +1 more source

Medicinal Cannabis for the Treatment of Chronic Refractory Pain: An Investigation of the Adverse Event Profile and Health-Related Quality of Life Impact of an Oral Formulation

Medical Cannabis and Cannabinoids, 2022
Introduction: Medicinal cannabis is prescribed in Australia for patients with chronic refractory pain conditions. However, measures of safety and effectiveness of different cannabinoids are lacking.
Sarah Abelev, Leon N. Warne, Melissa Benson, Mark Hardy, Sunny Nayee, John Barlow   +5 more
doaj   +1 more source

In-situ TD-GCMS measurements of oxidative products of monoterpenes at typical vaping temperatures: implications for inhalation exposure to vaping products

Scientific Reports, 2022
Vaping is gaining in popularity. However, there is still much that remains unknown about the potential risk and harms of vaping. Formation of oxidative products is one of such areas that are not well understood.
Jiping Zhu, Jianjun Niu, Dharani Das, Ashley Cabecinha, Hanan Abramovici   +4 more
doaj   +1 more source

Reasoning deficits among illicit drug users are associated with aspects of cannabis use [PDF]

, 2014
Background. Deficits in deductive reasoning have been observed among ecstasy/polydrug users. The present study seeks to investigate dose-related effects of specific drugs and whether these vary with the cognitive demands of the task. Methods. One hundred
AB Scholey, Andy M. Morley, AS Gilinsky, BF Zaldívar, C Montgomery, C Reverberi, C Reverberi, C Shikishima, C Shikishima, C Vignali, Catharine Montgomery, D Rodriguez-Moreno, F Hadjiefthyvoulou, F Indlekofer, Florentia Hadjiefthyvoulou, G Bedi, G Jager, G Jager, G Kanayama, GS Yacoubian Jr, J Raven, JE Fisk, JM Bland, John E. Fisk, KJ Gilhooly, KJ Gilhooly, KM Galotti, LK Jacobsen, M Bucciarelli, MJ Fernández-Serrano, MW Morris, N Pike, N Verschueren, PJ Cunha, PN Johnson-Laird, PN Murphy, S Khemlani, S Nakagawa, SR Narum, V Goel, Y Benjamini   +40 more
core   +3 more sources

Medicinal cannabis [PDF]

Australian Prescriber, 2015
A number of therapeutic uses of cannabis and its derivatives have been postulated from preclinical investigations. Possible clinical indications include spasticity and pain in multiple sclerosis, cancer-associated nausea and vomiting, cancer pain and HIV neuropathy.
openaire   +2 more sources

Risk assessment of metals measured in regulated Canadian dried cannabis and cannabis vaping products: case study and perspectives

Frontiers in Toxicology
In 2018, the Cannabis Act and its regulations established a strict legal framework for controlling production, distribution, sale and possession of cannabis across Canada.
Sathish Achuthan, Andrew Waye, Hanan Abramovici   +2 more
doaj   +1 more source

Assessing the bioactivity of cannabis extracts in larval zebrafish

Journal of Cannabis Research, 2021
Background Whole-plant cannabis extracts are consumed by the public for medical and non-medical (“recreational”) purposes but are poorly researched compared to pure cannabinoids.
Jessica Nixon, Hanan Abramovici, Ashley Cabecinha, Camilo Martinez-Farina, Joseph Hui, Lee Ellis   +5 more
doaj   +1 more source

Testing the Efficacy of a Prototype That Combines Ultrasound and Pulsed Electric Field for Extracting Valuable Compounds from Mitragyna speciosa Leaves

AgriEngineering, 2023
This work aimed to test the efficacy of an ultrasound (US) and pulsed electric field (PEF) apparatus to extract mitragynine from dried Mitragyna speciosa cv. Karn Dang leaves. Four modes of the device were tested: PEF, US, US + PEF, and PEF + US, and the
Raweeroj Jintawiwat, Natnakorn Punamorntarakul, Rossakornpat Hirunyasiri, Parkpoom Jarupoom, Tanachai Pankasemsuk, Supakiat Supasin, Arthitaya Kawee-ai   +6 more
doaj   +1 more source

Evaluating the role of a galanin enhancer genotype on a range of metabolic, depressive and addictive phenotypes [PDF]

, 2014
Funded by •ERC. Grant Number: 284167 •NIH. Grant Number: 1RO1DK0921127-01 •NWO.
Day, Ian, Farrer, Lindsay A, Gelernter, Joel, Heron, Jon, Hickman, Matthew, Kranzler, Henry R, Lewis, Glyn, MacKenzie, Alasdair, Minica, Camelia, Munafò, Marcus, Richardson, Tom G, Tavare, Jeremy, Vink, Jacqueline M, Wynick, David   +13 more
core   +2 more sources