Results 91 to 100 of about 721,383 (379)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Greater Boston Youth Symphony Orchestras Winter Concert, January 27, 1991 [PDF]
, 1991 This is the concert program of the Greater Boston Youth Symphony Winter Concert performance on Sunday, January 27, 1991 at 4:00 p.m., at the Boston University Concert Hall, 855 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Selection and Presentation of Texts in Early Medieval Canon Law Collections: Approaching the Codex Remensis (Berlin, Staatsbibliothek, Phill. 1743)* [PDF]
, 2021 Michael Eber +3 more
openalex +1 more source
Foreword Symposium: Fourth Annual Mid-Atlantic People ofColor Legal Scholarship Conference: Law and Literature: Examining the Limited Legal Imagination in the Traditional Legal Canon [PDF]
, 1998 The Fourth Annual Mid-Atlantic People of Color Legal Scholarship Conference, which took place at Rutgers Law School in Camden on February 12-14, 1998, poignantly captured the theme around which the conference was organized.
Foster, Sheila R.
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The Journal of Symbolic Logic, 2009 AbstractWe develop canonical rules capable of axiomatizing all systems of multiple-conclusion rules overK4 orIPC, by extension of the method of canonical formulas by Zakharyaschev [37]. We use the framework to give an alternative proof of the known analysis of admissible rules in basic transitive logics, which additionally yields the following ...
openaire +3 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Holy Selfie in Catholicism and Eastern Orthodoxy: A Comparative Analysis of the New Visual Canon [PDF]
, 2020 Sophia V. Tikhonova +1 more
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The Art History Canon and the Art History Survey Course: Subverting the Western Narrative. [PDF]
, 2019 Art History enrollments at the college level are declining as students flock to STEM majors and perceive Art History as dated and of little use in today’s modern, scientific world. Yet Art History classes can teach valuable skills. When taught in a broad
Mast, Kimberly Becker
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source