Results 51 to 60 of about 721,383 (379)
The role of fibroblast growth factors in cell and cancer metabolism
FEBS Letters, EarlyView.Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley +1 more source
Legal Classics: After Deconstructing the Legal Canon [PDF]
, 1994 The debate over the canon has gripped the University in recent years. Defenders of the canon argue that canonical texts embody timeless and universal themes, but critics argue that the process of canonization subordinates certain people and viewpoints ...
Mootz, Francis J., III
core +2 more sources
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
The formation of the Christian biblical canon [PDF]
, 1996 Reviewed Book: McDonald, Lee M. The formation of the Christian biblical canon.
Miller, John W.
core +1 more source
ON CANONICAL CONSTRUCTIONS. II [PDF]
Proceedings of the National Academy of Sciences, 1955 In the second paper in this series [2; 3], it was demonstrated that under suitable topological conditions on a space S (which are in particular always satisfied for a manifold), the problem of reconstructing S from its group G of homeomorphism onto itself may be reduced to the problem of reconstructing the points of S from G.
openaire +7 more sources
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
FEBS Letters, EarlyView.We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Journal of Translational Medicine, 2020 Background Intracranial aneurysms (IAs) are dangerous because of their potential to rupture. We previously found significant RNA expression differences in circulating neutrophils between patients with and without unruptured IAs and trained machine ...
Kerry E. Poppenberg +13 more
doaj +1 more source
The Ethical Dilemma of Campaigning for Judicial Office: A Proposed Solution [PDF]
, 1986 Candidates for judicial office looked to the Canons of Judicial Ethics for the appropriate behavior expected of a candidate during a judicial campaign. Canons 30 and 32 require candidates to remain free from an appearance of influence by those who have ...
core +1 more source
Canonical varieties with no canonical axiomatisation [PDF]
Transactions of the American Mathematical Society, 2004 We give a simple example of a varietyV\mathbf {V}of modal algebras that is canonical but cannot be axiomatised by canonical equations or first-order sentences. We then show that the varietyRRA\mathbf {RRA}of representable relation algebras, although canonical, has no canonical axiomatisation. Indeed, we show that every axiomatisation of these varieties
Hodkinson, I., Venema, Y.
openaire +5 more sources
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source