Results 81 to 90 of about 687,072 (327)

The Epistemology of “Epistemology Naturalized” [PDF]

open access: yes, 1999
Quine's “Epistemology Naturalized” has become part of the canon in epistemology and excited a widespread revival of interest in naturalism. Yet the status accorded the essay is ironic, since both friends and foes of philosophical naturalism deny that ...
Roth, Paul
core   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Log–canonical forms and log canonical singularities

open access: yesMathematische Nachrichten, 2003
AbstractFor a normal subvarietyVof ℂnwith a good ℂ*–action we give a simple characterization for when it has only log canonical, log terminal or rational singularities. Moreover we are able to give formulas for the plurigenera of isolated singular points of such varieties and of the logarithmic Kodaira dimension ofV\{0}.
Zaidenberg, Mikhail, Flenner, Hubert
openaire   +4 more sources

Marcion and the Canon [PDF]

open access: green, 1907
J. Rendel Harris
openalex   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

open access: yesMolecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban   +12 more
wiley   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Foreword: Revisiting Gilson and Kraakman’s Efficiency Story [PDF]

open access: yes, 2003
Gilson and Kraakman\u27s ‘Mechanisms of Market Efficiency’ is part of the canon of modem corporate law scholarship, one of a handful of articles that has profoundly influenced the way we think about the field.
Langevoort, Donald C.
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

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