Results 161 to 170 of about 299,088 (201)

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

Improving risk stratification and detection of early HCC using ultrasound-based deep learning models. [PDF]

JHEP Rep
Dana J, Meyer A, Paisant A, Rode A, Sartoris R, Séror O, Cassinotto C, Milot L, Grégory J, Cœur J, Lebigot J, Schembri V, Villeret F, Takeda AN, Ronot M, Vilgrain V, Baumert TF, Gallix B, Padoy N, Nahon P.   +19 more
europepmc   +1 more source

Return to Your Baptism Daily : Baptism and Christian Life [PDF]

, 2015
Wood, Susan K.
core   +1 more source

An Artificial Antibody‐Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome

Advanced Science, EarlyView.
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He, Anqi Zhang, Zhanchen Guo, Qi Li, Song Gao, Wenyan Guan, Ying Li, Jingran Chen, Sijia Sun, Jian He, Zhen Liu   +10 more
wiley   +1 more source

CT-guided Thermal Ablation of Liver Tumors Using Intraprocedural CT-CT Fusion for Applicator Position and Ablation Completeness Assessment: a Single-Center Comparative Analysis. [PDF]

Cardiovasc Intervent Radiol
Verdonschot KHM, Jenniskens SFM, van den Boezem PB, Tjwa ETTL, de Wilt JHW, Fütterer JJ, Stommel MWJ, Overduin CG.   +7 more
europepmc   +1 more source

Engineering Compact Base Editors by AlphaFold‐Guided Mutation Scan and Escherichia coli‐Based Tri‐Selection

Advanced Science, EarlyView.
A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son, Goeun Kim, Jungjoon K. Lee   +2 more
wiley   +1 more source

In vitro production significantly reduces metabolic differences among bovine embryos. [PDF]

Metabolomics
Laloë D, Gatien J, Dupuy C, Archilla C, Laffont L, Ruffini S, Canon E, Le Bourhis D, Deloche MC, Dubois O, Leguienne B, Nadal-Desbarats L, Calderari S, Escouflaire C, Desnoes O, Schibler L, Salvetti P, Duranthon V.   +17 more
europepmc   +1 more source

Presidential Signing Statements Under the Bush Administration: A Threat to Checks and Balances and the Rule of Law?: Hearing Before the H. Comm. on the Judiciary, 110th Cong., Jan. 31, 2007 (Statement of Nicholas Quinn Rosenkranz, Prof. of Law, Geo. U. L. Center) [PDF]

, 2007
Rosenkranz, Nicholas Quinn
core   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source

Pre-procedural computed tomography predicts procedural complexity and complications in bidirectional rotational mechanical transvenous lead extraction. [PDF]

Europace
Migliore F, Pittorru R, Tarzia V, Rosso J, De Lazzari M, Ziggiotto A, Zancanaro G, Winnicki G, Gemelli M, Micciolo M, Guerrieri A, Margheri D, Motta R, Pergola V, Gerosa G, Corrado D.   +15 more
europepmc   +1 more source