Results 31 to 40 of about 41,884 (217)
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Topological Ramsey spaces from Fra\"iss\'e classes, Ramsey-classification theorems, and initial structures in the Tukey types of p-points [PDF]
, 2015 A general method for constructing a new class of topological Ramsey spaces is presented. Members of such spaces are infinite sequences of products of Fra\"iss\'e classes of finite relational structures satisfying the Ramsey property.
Dobrinen, Natasha +2 more
core +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
, 2003 Let Lag(E) be the grassmannian of lagrangian subspaces of a complex symplectic vector space E. We construct a Maslov class which generates the second integral cohomology of Lag(E), and we show that its mod 2 reduction is the characteristic class of a ...
Alan Weinstein +5 more
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Exact nonclassical symmetry solutions of Arrhenius reaction-diffusion
, 2015 Exact solutions for nonlinear Arrhenius reaction-diffusion are constructed in $n$ dimensions. A single relationship between nonlinear diffusivity and the nonlinear reaction term leads to a nonclassical Lie symmetry whose invariant solutions have a heat ...
Bradshaw-Hajek, B. H. +2 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Geometry of curves in parabolic homogeneous spaces
, 2013 The current paper is devoted to the study of integral curves of constant type in parabolic homogeneous spaces. We construct a canonical moving frame bundle for such curves and give the criterium when it turns out to be a Cartan connection ...
Doubrov, Boris, Zelenko, Igor
core +1 more source