Results 51 to 60 of about 6,243,426 (248)
矿业科学学报Data governance capability is fundamental to coal mine intelligence construction. It could accelerate the intelligent construction of coal mines and promote the digital transformation of the coal industry so as to building a modern energy system in ...
WANG Meijun +3 more
doaj +1 more source
Journal of Innovation Management, 2018 Design thinking in the management context has suffered from vague definition, gaps in literature, and lack of theoretical foundation. Research streams in absorptive capacity and dynamic capabilities have reached a point of convergence with respect to ...
Brad Cousins
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Vision Impossible? Some Aspects of the Current Russian Debates about the Military Sciences
Journal on Baltic Security, 2015 In 21st century military theory and doctrine, it is common to subdivide military capability into conceptual, physical and moral components. At least in theory, it follows that conceptual capability should be regarded as the crucial link between the ...
Eklund Niklas
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Applying control theory to capability measurement scales
, 2009 Capability and maturity models are widely accepted. Generally the first three levels of most capability models have the same general goal, a defined repeatable process, but may differ in their implementation of that goal.
McBride, T
core
IEEE Access, 2018 Flight performance calculation is an important part of the micro flapping wing air vehicle design. It is used to verify whether the air vehicle design meets the performance requirements so as to make targeted improvements to the design.
Jianlin Xuan, Z. Yang, P. Nian, D. Ma
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
A Dynamic Operationalization of Sen’s Capability Approach [PDF]
The limits of the utilitarian approach have led to a search for different notions of welfare. The income approach to well-being, in fact, doesn’t account for the diversity in human beings and for the heterogeneities of contingent circumstances.
Marco Grasso
core +2 more sources