Results 71 to 80 of about 1,295,083 (302)

Strategic goal interdependence approach to dynamic capability and the effects of customer integration and market dynamism: evidence from China

open access: yesSystems Science & Control Engineering, 2019
Based on the theory of cooperation and competition, this study proposed goal interdependence with downstream company as an important enabler of firms’ dynamic capability.
Lin-Bo Yang, Chen-Jing Gan
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Evolutionary stable strategies for business innovation and knowledge transfer

open access: yesInternational Journal of Innovation Studies, 2019
Evolutionary game theory expands into a number of areas that go beyond the biological concept of evolution to include sociology, economics, and business management.
Ela Ozkan-Canbolat, Aydin Beraha
doaj   +1 more source

Digital Transformation, Dynamic Capabilities and Enterprise Innovation Performance Based on Dynamic Capability Theory and Upper Echelon Theory

open access: yes, 2023
In the era of digital economy, digital transformation has become a hot issue for both academia and industry, especially for those manufacturing enterprises that are not “naturally digital”, it is important to use digitalization to reconstruct their capabilities and drive their innovation development.
Jin, Yuan, Xu, Hong, Su, Xujuan
openaire   +1 more source

Double Ionisation in R-Matrix Theory Using a 2-electron Outer Region [PDF]

open access: yes, 2015
We have developed a two-electron outer region for use within R-matrix theory to describe double ionisation processes. The capability of this method is demonstrated for single-photon double ionisation of He in the photon energy region between 80 eV to 180
Parker, J. S.   +2 more
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Supercapacitor assisted LDO (SCALDO) techniquean extra low frequency design approach to high efficiency DC-DC converters and how it compares with the classical switched capacitor converters [PDF]

open access: yes, 2013
Supercapacitor assisted low dropout regulators (SCALDO) were proposed as an alternative design approach to DC-DC converters, where the supercapacitor circulation frequency (switching frequency) is in the order of few Hz to few 10s of Hz, with an output ...
Kankanamge, Kosala, Kularatna, Nihal
core   +3 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Strategic decision-making logics, entrepreneurial capability and opportunity exploitation in high-tech new ventures

open access: yesJournal of Business Economics and Management, 2018
This paper aims at exploring the influences of effectuation and causation on opportunity exploitation in high-tech new ventures and the mediating role of entrepreneurial capability by integrating effectuation theory and a perspective of entrepreneurial ...
Runping Guo
doaj   +1 more source

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