Results 61 to 70 of about 1,295,083 (302)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
An Agency‐Based Capability Theory of Justice
AbstractThe capability approach is one of the main contenders in the field of theorizing social justice. Each citizen is entitled to a set of basic capabilities. But which are these? Martha Nussbaum formulated a set of ten central capabilities. Amartya Sen argued they should be selected in a process of public reasoning. Critics object that the Nussbaum‐
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Vision Impossible? Some Aspects of the Current Russian Debates about the Military Sciences
In 21st century military theory and doctrine, it is common to subdivide military capability into conceptual, physical and moral components. At least in theory, it follows that conceptual capability should be regarded as the crucial link between the ...
Eklund Niklas
doaj +1 more source
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Flight performance calculation is an important part of the micro flapping wing air vehicle design. It is used to verify whether the air vehicle design meets the performance requirements so as to make targeted improvements to the design.
Jianlin Xuan, Z. Yang, P. Nian, D. Ma
doaj +1 more source
BackgroundAlthough there is a rise in the use of mobile health (mHealth) tools to support chronic disease management, evidence derived from theory-driven design is lacking.
Sittig, Scott +4 more
doaj +1 more source
Wavepacket Dynamics, Quantum Reversibility and Random Matrix Theory
We introduce and analyze the physics of "driving reversal" experiments. These are prototype wavepacket dynamics scenarios probing quantum irreversibility.
Alhassid +44 more
core +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Data governance capability is fundamental to coal mine intelligence construction. It could accelerate the intelligent construction of coal mines and promote the digital transformation of the coal industry so as to building a modern energy system in ...
WANG Meijun +3 more
doaj +1 more source

