Results 61 to 70 of about 1,295,083 (302)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

An Agency‐Based Capability Theory of Justice

open access: yesEuropean Journal of Philosophy, 2016
AbstractThe capability approach is one of the main contenders in the field of theorizing social justice. Each citizen is entitled to a set of basic capabilities. But which are these? Martha Nussbaum formulated a set of ten central capabilities. Amartya Sen argued they should be selected in a process of public reasoning. Critics object that the Nussbaum‐
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Vision Impossible? Some Aspects of the Current Russian Debates about the Military Sciences

open access: yesJournal on Baltic Security, 2015
In 21st century military theory and doctrine, it is common to subdivide military capability into conceptual, physical and moral components. At least in theory, it follows that conceptual capability should be regarded as the crucial link between the ...
Eklund Niklas
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Calculation Methods of Flight Performance of Flapping Wing Aircrafts Based on Energy Theory and Slipstream Theory (September 2018)

open access: yesIEEE Access, 2018
Flight performance calculation is an important part of the micro flapping wing air vehicle design. It is used to verify whether the air vehicle design meets the performance requirements so as to make targeted improvements to the design.
Jianlin Xuan, Z. Yang, P. Nian, D. Ma
doaj   +1 more source

Incorporating Behavioral Trigger Messages Into a Mobile Health App for Chronic Disease Management: Randomized Clinical Feasibility Trial in Diabetes

open access: yesJMIR mHealth and uHealth, 2020
BackgroundAlthough there is a rise in the use of mobile health (mHealth) tools to support chronic disease management, evidence derived from theory-driven design is lacking.
Sittig, Scott   +4 more
doaj   +1 more source

Wavepacket Dynamics, Quantum Reversibility and Random Matrix Theory

open access: yes, 2005
We introduce and analyze the physics of "driving reversal" experiments. These are prototype wavepacket dynamics scenarios probing quantum irreversibility.
Alhassid   +44 more
core   +2 more sources

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Research on evaluation and promotion strategy of data governance capability for intelligent coal mines

open access: yes矿业科学学报
Data governance capability is fundamental to coal mine intelligence construction. It could accelerate the intelligent construction of coal mines and promote the digital transformation of the coal industry so as to building a modern energy system in ...
WANG Meijun   +3 more
doaj   +1 more source

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