Results 121 to 130 of about 2,918,690 (278)

Nonprofit "Capacity-Building Orientation": The Role of Learning in Building Nonprofit Performance [PDF]

, 2005
Amidst increasing attention to nonprofit performance, interest in nonprofit capacity building activities has understandably intensified. A natural outgrowth of this interest is an expansion in the number and range of nonprofit capacity-building providers

core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Building eResearch Services, Capabilities and Capacity [PDF]

, 2009
The Queensland University of Technology (QUT) is known for several flagship eResearch centres. It also has a number of mature, centralised research support services that address a several of areas of eResearch.
Borchert, Martin, Young, Joseph A.
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Training report: capacity building in entrepreneurial and business skills for operationalizing fresh cassava roots packhouse. [PDF]

, 2017
This report describes the capacity building process and activities that were done to enhance the business and entrepreneurial skills of packhouse ...
Abass, A., Kaliisa, R., Kwagala, I., Matovu, Moses, Menya, G, Muyinza, H., Nanyondo, R., Nuwamanya, E., Nyakaisiki, E., Nyamutoka, P., Wanda, K.   +10 more
core   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Experiences and perspectives on traditional and faith healers’ involvement in the care of people with severe mental health conditions in ethiopia: a scoping review

International Journal of Mental Health Systems
Background Traditional and faith healers (TFHs) play a prominent role in the care of people with severe mental health conditions (MHCs) in many countries.
Mekonnen Tsehay, Teshome Shibre Kelkile, Wubalem Fekadu, Alex Cohen, Desalegn Kiros, Charlotte Hanlon   +5 more
doaj   +1 more source

Resource Directory for Nonprofit Capacity Building in California's Central Valley [PDF]

, 2006
Provides an overview of recent studies of Central Valley's nonprofit sector, and a list of consultants, foundations, community organizations, and other institutions that provide capacity building services and resources to nonprofit ...

core  

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source