Results 51 to 60 of about 49,464 (141)

First efficacy results of capecitabine with anthracycline- and taxane-based adjuvant therapy in high-risk early breast cancer: a meta-analysis.

PLoS ONE, 2012
BackgroundCapecitabine is effective and indicated for the salvage treatment of metastatic breast cancer. Therefore, it is essential to evaluate the efficacy of capecitabine in the adjuvant setting.
Yiwei Jiang, Wenjin Yin, Liheng Zhou, Tingting Yan, Qiong Zhou, Yueyao Du, Zhenzhou Shen, Zhimin Shao, Jinsong Lu   +8 more
doaj   +1 more source

Benefit and safety of capecitabine after resection of biliary tract cancer: a real-world study with propensity score matching

Frontiers in Oncology
Biliary tract cancer (BTC) is a high mortality disease, with few patients eligible for resection. Even post-surgery, recurrence rates remain high. The benefit of capecitabine as adjuvant therapy is uncertain, as seen in the BILCAP trial results.
Hugo Roussel, Sophie Le Joncour, Valerie Aurillac, Arthur Marichez, Jean Frederic Blanc, Laurence Chiche, Christophe Laurent, Marie Decraecker   +7 more
doaj   +1 more source

Adverse Interaction between Capecitabine and Warfarin Resulting in Altered Coagulation Parameters: A Review of the Literature Starting from a Case Report

Case Reports in Medicine, 2010
Capecitabine is an orally active prodrug of fluorouracil and is extensively used as an antineoplastic agent. It is converted to 5-Fluorouracil in the liver and tumor tissues.
Giovanni Giunta
doaj   +1 more source

044. Unlocking The Potential: Comparing The Effects of Probiotics Alone and in Combination with Capecitabine Against Colorectal Cancer in Rats

JBN (Jurnal Bedah Nasional)
Background: Colorectal cancer (CRC) is a leading cause of cancer deaths globally. While capecitabine is an effective chemotherapy for CRC, its use is limited by side effects and resistance. This has sparked interest in combining capecitabine with natural
Reza Yuneri Putri, Suci Berlian Hemilton, Muhammad Iqbal Rivai, Rini Suswita, Irwan Irwan, Avit Suchitra   +5 more
doaj   +1 more source

Capecitabine-induced coronary artery vasospasm in a patient who previously experienced a similar episode with fluorouracil therapy

Türk Kardiyoloji Derneği Arşivi, 2016
Capecitabine is a chemotherapeutic agent used in the treatment of metastatic colon cancer and metastatic breast cancer. It is metabolized into fluorouracil (5-FU) in the liver; hence, its mechanism of action is similar to that of 5-FU.
Uğur Nadir Karakulak, Elifcan Aladağ, Naresh Maharjan, Kenan Övünç   +3 more
doaj   +1 more source

Photosensitive lichenoid skin reaction to capecitabine

BMC Cancer, 2017
Background Capecitabine is an oral prodrug of fluorouracil, which is a common agent used in the management of many solid tumor malignancies. Dermatologic reaction is common with various chemotherapy agents but is not commonly reported in the use of ...
Rena A. Shah, Daniel D. Bennett, Mark E. Burkard   +2 more
doaj   +1 more source

Ixabepilone as Monotherapy or in Combination with Capecitabine for the Treatment of Advanced Breast Cancer

Breast Cancer: Basic and Clinical Research, 2011
Breast Cancer is the most prevalent cancer in the world with 4.4 million survivors up to 5 years following the diagnosis. 1 In the US alone approximately forty thousand women die annually of metastatic breast cancer (MBC). Despite many effective systemic
Katherine H. Rak Tkaczuk
doaj   +1 more source

Clinical observation of capecitabine in the maintenance treatment of advanced breast cancer

Zhongguo aizheng zazhi, 2014
Background and purpose: Capecitabine, which is widely used in the first-line treatment of advanced breast cancer, was known little in the maintenance treatment of advanced breast cancer.
李剑英, 季从飞, 陈佳, 谭清和
doaj  

Capecitabine-induced cicatricial ectropion: A case review

The Pan-American Journal of Ophthalmology
Capecitabine, an oral prodrug of 5-fluorouracil (5-FU), offers a more targeted chemotherapeutic approach, reducing systemic side effects. However, cases of ocular side effects have been described in the literature. We report the case of a 94-year-old man
Stuti Misty Tanya, Andrea Dahoud, Ahmed Al-Amer, Bryan Arthurs, Christian El-Hadad   +4 more
doaj   +1 more source

A pilot study investigating plasma pharmacokinetics and tolerance of oral capecitabine in carcinoma-bearing dogs

BMC Veterinary Research
Background Capecitabine is an oral prodrug of the active metabolite 5-fluorouracil, which has been used effectively in human colorectal, head and neck, and mammary carcinomas.
Sarah Wetzel, Janean Fidel, Dale Whittington, Nicolas F. Villarino   +3 more
doaj   +1 more source