Results 11 to 20 of about 642,458 (299)

GPIHBP1 Is Responsible for the Entry of Lipoprotein Lipase into Capillaries

Cell Metabolism, 2010
SUMMARY The lipolytic processing of triglyceride-rich lipoproteins by lipoprotein lipase (LPL) is the central event in plasma lipid metabolism, providing lipids for storage in adipose tissue and fuel for vital organs such as the heart. LPL is synthesized
Brandon S. J. Davies, A. Beigneux, R. H. Barnes, Yi-Ping Tu, P. Gin, Michael M. Weinstein, Chika Nobumori, Rakel Nyrén, I. Goldberg, G. Olivecrona, A. Bensadoun, S. Young, L. Fong   +12 more
semanticscholar   +2 more sources

Mechanics of blood flow in capillaries [PDF]

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
2nd Micro and Nano Flows Conference (MNF2009), Secomb, TW   +1 more
core   +6 more sources

Amyloid β oligomers constrict human capillaries in Alzheimer’s disease via signaling to pericytes

Science, 2019
Pericytes put the squeeze on cognition Like a computer, the brain needs a reliable source of power, which is provided as oxygen and glucose in the blood. However, in many neurological disorders this energy supply is disrupted.
R. Nortley, Nils Korte, P. Izquierdo, Chanawee Hirunpattarasilp, Anusha Mishra, Z. Jaunmuktane, V. Kyrargyri, Thomas Pfeiffer, Lila Khennouf, C. Madry, Hui Gong, A. Richard-Loendt, Wen-Hui Huang, T. Saito, T. Saido, S. Brandner, H. Sethi, D. Attwell   +17 more
semanticscholar   +1 more source

Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer’s disease mouse models

Nature Neuroscience, 2019
Cerebral blood flow (CBF) reductions in Alzheimer’s disease patients and related mouse models have been recognized for decades, but the underlying mechanisms and resulting consequences for Alzheimer’s disease pathogenesis remain poorly understood. In APP/
Jean C. Cruz Hernández, O. Bracko, Calvin J. Kersbergen, Victorine Muse, Mohammad Haft-Javaherian, Maxime Berg, Laibaik Park, Lindsay K. Vinarcsik, Iryna Ivasyk, Daniel A. Rivera, Y. Kang, Marta Cortes-Canteli, Myriam Peyrounette, V. Doyeux, Amy Smith, Joan Zhou, G. Otte, Jeffrey D. Beverly, Elizabeth Davenport, Y. Davit, Charles Lin, S. Strickland, C. Iadecola, S. Lorthois, N. Nishimura, C. Schaffer   +25 more
semanticscholar   +1 more source

Is the microvasculature tone increasing with arterial hypertension?

Alʹmanah Kliničeskoj Mediciny, 2019
Rationale: An increase in vascular tone is believed to be a major factor leading to arterial hypertension (AH). There are no means for a direct measurement of the vascular tone in clinical practice.
D. A. Rogatkin, P. A. Glazkova, D. A. Kulikov, A. A. Glazkov, S. A. Terpigorev, G. G. Shekhyan, K. A. Kozlova, M. B. Makmatov-Rys   +7 more
doaj   +1 more source

Retinal oxygen supply shaped the functional evolution of the vertebrate eye

eLife, 2019
The retina has a very high energy demand but lacks an internal blood supply in most vertebrates. Here we explore the hypothesis that oxygen diffusion limited the evolution of retinal morphology by reconstructing the evolution of retinal thickness and the
Christian Damsgaard, Henrik Lauridsen, Anette MD Funder, Jesper S Thomsen, Thomas Desvignes, Dane A Crossley II, Peter R Møller, Do TT Huong, Nguyen T Phuong, H William Detrich III, Annemarie Brüel, Horst Wilkens, Eric Warrant, Tobias Wang, Jens R Nyengaard, Michael Berenbrink, Mark Bayley   +16 more
doaj   +1 more source

Efficacy and safety of oral pulmonary vasodilators in pulmonary veno‐occlusive disease

Pulmonary Circulation, 2022
Pulmonary veno‐occlusive disease (PVOD) or pulmonary capillary hemangiomatosis (PCH) is a rare subtype of pulmonary hypertension with dismal prognosis.
Junichi Nakamura, Ichizo Tsujino, Hideki Shima, Toshitaka Nakaya, Ayako Sugimoto, Takahiro Sato, Taku Watanabe, Hiroshi Ohira, Masaru Suzuki, Satonori Tsuneta, Ryo Hisada, Masaru Kato, Satoshi Konno   +12 more
doaj   +1 more source

Cellular changes at the glia-neuro-vascular interface in definite idiopathic normal pressure hydrocephalus

Frontiers in Cellular Neuroscience, 2022
Idiopathic normal pressure hydrocephalus (iNPH) is a subtype of dementia with overlap toward Alzheimer's disease. Both diseases show deposition of the toxic metabolites amyloid-β and tau in brain.
Per Kristian Eide, Per Kristian Eide
doaj   +1 more source

Modeling of water rising in systems of cylindrical capillaries of different radii

Advanced Engineering Research, 2016
The promotion of water in the systems of cylindrical capillaries is studied in detail. A mathematical model of the water movement in both symmetric and asymmetric capillaries connected to a vertical capillary is built.
Iosif A. Kipnis, Yury M. Vernigorov
doaj   +1 more source

A network of trans-cortical capillaries as mainstay for blood circulation in long bones

Nature Metabolism, 2019
Closed circulatory systems underlie the function of vertebrate organs, but in long bones their structure is unclear although they constitute the exit route for bone marrow (BM) leukocytes.
A. Grüneboom, I. Hawwari, D. Weidner, S. Culemann, Sylvia Müller, Sophie Henneberg, Alexandra Brenzel, Simon F. Merz, L. Bornemann, Kristina Zec, M. Wuelling, Lasse Kling, M. Hasenberg, Sylvia Voortmann, Stefanie C. Lang, W. Baum, Alexandra Ohs, O. Kraff, H. Quick, Marcus Jäger, S. Landgraeber, M. Dudda, R. Danuser, J. Stein, M. Rohde, K. Gelse, Annette I. Garbe, Alexandra Adamczyk, A. Westendorf, D. Hoffmann, S. Christiansen, D. Engel, A. Vortkamp, G. Krönke, M. Herrmann, T. Kamradt, G. Schett, A. Hasenberg, M. Gunzer   +38 more
semanticscholar   +1 more source