Results 1 to 10 of about 10,316 (244)
Pericytes for Therapeutic Approaches to Ischemic Stroke [PDF]
Frontiers in Neuroscience, 2021 Pericytes are perivascular multipotent cells located on capillaries. Although pericytes are discovered in the nineteenth century, recent studies have found that pericytes play an important role in maintaining the blood—brain barrier (BBB) and regulating ...
Lu Cao +4 more
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The Neuroinflammatory Role of Pericytes in Epilepsy
Biomedicines, 2021 Pericytes are a component of the blood–brain barrier (BBB) neurovascular unit, in which they play a crucial role in BBB integrity and are also implicated in neuroinflammation. The association between pericytes, BBB dysfunction, and the pathophysiology of
Gaku Yamanaka +6 more
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Emerging Role of Pericytes and Their Secretome in the Heart
Cells, 2021 Pericytes, as mural cells covering microvascular capillaries, play an essential role in vascular remodeling and maintaining vascular functions and blood flow.
Jian-Xiong Chen, Aubrey Cantrell
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Tissue Specific Origin, Development, and Pathological Perspectives of Pericytes
Frontiers in Cardiovascular Medicine, 2018 Pericytes are mural cells surrounding blood vessels, adjacent to endothelial cells. Pericytes play critical roles in maturation and maintenance of vascular branching morphogenesis.
Tomoko Yamazaki +2 more
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Biology and function of pericytes in the vascular microcirculation
Animal Models and Experimental Medicine, 2023 Pericytes are the main cellular components of tiny arteries and capillaries. Studies have found that pericytes can undergo morphological contraction or relaxation under stimulation by cytokines, thus affecting the contraction and relaxation of ...
Ping Yuan, Jinming Liu
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The Role of Pericytes in Regulation of Innate and Adaptive Immunity
Biomedicines, 2023 Pericytes are perivascular multipotent cells wrapping microvascular capillaries, where they support vasculature functioning, participate in tissue regeneration, and regulate blood flow.
Siarhei A. Dabravolski +6 more
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Pericytes as mediators of infiltration of macrophages in multiple sclerosis
Journal of Neuroinflammation, 2021 Background Multiple sclerosis (MS) is a neurodegenerative condition of the central nervous system (CNS). It is associated with blood–brain barrier (BBB) breakdown and intravasation of leukocytes, particularly monocyte-derived macrophages, into the CNS ...
Deepak Kumar Kaushik +3 more
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Matricellular Protein Periostin Promotes Pericyte Migration in Fibrotic Airways
Frontiers in Allergy, 2021 Introduction: Periostin is a matricellular protein that is currently used as a biomarker for asthma. However, its contribution to tissue remodeling in allergic asthma is currently unknown.
Rebecca E. Bignold, Jill R. Johnson
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Descending Vasa Recta Endothelial Membrane Potential Response Requires Pericyte Communication. [PDF]
PLoS ONE, 2016 Using dual-cell electrophysiological recording, we examined the routes for equilibration of membrane potential between the pericytes and endothelia that comprise the descending vasa recta (DVR) wall.
Zhong Zhang +2 more
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Pericytes in Cerebrovascular Diseases: An Emerging Therapeutic Target
Frontiers in Cellular Neuroscience, 2019 Pericytes are functional components of the neurovascular unit (NVU) that are located around the blood vessels, and their roles in the regulation of cerebral health and diseases has been reported.
Xiaojuan Su +8 more
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