Results 31 to 40 of about 62,021 (301)

Capillary pericytes express α-smooth muscle actin, which requires prevention of filamentous-actin depolymerization for detection

open access: yeseLife, 2018
Recent evidence suggests that capillary pericytes are contractile and play a crucial role in the regulation of microcirculation. However, failure to detect components of the contractile apparatus in capillary pericytes, most notably α-smooth muscle actin
Luis Alarcon-Martinez   +7 more
doaj   +1 more source

The role played by perivascular cells in kidney interstitial injury [PDF]

open access: yes, 2014
Fibrosis of the kidney is a disease affecting millions worldwide and is a harbinger of progressive loss of organ function resulting in organ failure. Recent findings suggest that understanding mechanisms of development and progression of fibrosis will ...
林水龍   +1 more
core   +1 more source

Pericyte Loss in Diseases

open access: yesCells, 2023
Pericytes are specialized cells located in close proximity to endothelial cells within the microvasculature. They play a crucial role in regulating blood flow, stabilizing vessel walls, and maintaining the integrity of the blood–brain barrier. The loss of pericytes has been associated with the development and progression of various diseases, such as ...
Pengfei Li, Hongkuan Fan
openaire   +3 more sources

Pericytes and the pathogenesis of diabetic retinopathy [PDF]

open access: yes, 2002
Pericytes provide vascular stability and control endothelial proliferation. Pericyte loss, microaneurysms, and acellular capillaries are characteristic for the diabetic retina.
Lundqvist, A   +7 more
core   +1 more source

Spatiotemporal dynamics of PDGFRβ expression in pericytes and glial scar formation in penetrating brain injuries in adults [PDF]

open access: yes, 2019
Aims: Understanding the spatiotemporal dynamics of reactive cell types following brain injury is important for future therapeutic interventions. We have previously used penetrating cortical injuries following intracranial recordings as a brain repair ...
S. M. Sisodiya   +9 more
core   +1 more source

Brain pericyte biology: from physiopathological mechanisms to potential therapeutic applications in ischemic stroke

open access: yesFrontiers in Cellular Neuroscience, 2023
Pericytes play an indispensable role in various organs and biological processes, such as promoting angiogenesis, regulating microvascular blood flow, and participating in immune responses.
Jiaqi Fu   +6 more
doaj   +1 more source

Pericytes

open access: yesFrontiers in Physiology, 2023
Pericytes are a heterogeneous population of mesenchymal cells located on the abluminal surface of microvessels, where they provide structural and biochemical support. Pericytes have been implicated in numerous lung diseases including pulmonary arterial hypertension (PAH) and allergic asthma due to their ability to differentiate into scar-forming ...
Garrison, Annelise T.   +3 more
openaire   +1 more source

Pericytes on the move [PDF]

open access: yesPflügers Archiv - European Journal of Physiology, 2013
Pericytes were originally discovered more than100 years ago as contractile cells surrounding the endothelial cells of small blood vessels. Anatomists have later on strictly defined pericytes as cells sharing a basal membrane with the endothelium.
openaire   +3 more sources

Pericytes are activated around glioma. [PDF]

open access: yes, 2015
(A) Low magnification photomicrograph of a normal rgs5GFP/+ mouse brain, scale bar is 500 μm. (B) Under normal conditions, quiescent GFP positive pericytes showed a flat morphology with a small cell body (arrows), scale bar is 20 μm.
Ilknur Özen (326200)   +4 more
core   +1 more source

Contractile apparatus in CNS capillary pericytes [PDF]

open access: yes, 2022
Significance: Whether or not capillary pericytes contribute to blood flow regulation in the brain and retina has long been debated. This was partly caused by failure of detecting the contractile protein alpha-smooth muscle actin (alpha-SMA) in capillary ...
DALKARA, TURGAY   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy