Results 31 to 40 of about 87,628 (306)

Pericyte mechanics and mechanobiology [PDF]

open access: yesJournal of Cell Science, 2021
ABSTRACT Pericytes are mural cells of the microvasculature, recognized by their thin processes and protruding cell body. Pericytes wrap around endothelial cells and play a central role in regulating various endothelial functions, including angiogenesis and inflammation.
Claire A. Dessalles   +2 more
openaire   +3 more sources

Brain pericyte biology: from physiopathological mechanisms to potential therapeutic applications in ischemic stroke

open access: yesFrontiers in Cellular Neuroscience, 2023
Pericytes play an indispensable role in various organs and biological processes, such as promoting angiogenesis, regulating microvascular blood flow, and participating in immune responses.
Jiaqi Fu   +6 more
doaj   +1 more source

The blood labyrinthine barrier in the human normal and Meniere's disease macula utricle. [PDF]

open access: yes, 2017
The ultrastructural organization of the blood labyrinthine barrier (BLB) was investigated in the human vestibular endorgan, the utricular macula, using postmortem specimens from individuals with documented normal auditory and vestibular function and ...
Ishiyama, Akira   +4 more
core   +2 more sources

Neuroinflammation and myelin status in Alzheimer’s disease, Parkinson’s disease, and normal aging brains: A small sample study [PDF]

open access: yes, 2019
Microglia and astrocytes play important roles in mediating the immune processes and nutritional support in the central nervous system (CNS). Neuroinflammation has been indicated in the progression of neurodegenerative diseases Alzheimer’s disease (AD ...
Benzinger, Tammie L. S.   +7 more
core   +2 more sources

Immune regulation by pericytes: modulating innate and adaptive immunity

open access: yesFrontiers in Immunology, 2016
Pericytes are mural cells that surround endothelial cells in small blood vessels. Pericytes have traditionally been credited with structural functions, being essential for vessel maturation and stabilization.
Rocio Navarro   +3 more
doaj   +1 more source

Diabetic retinopathy: could the alpha-1 antitrypsin be a therapeutic option? [PDF]

open access: yes, 2014
Diabetic retinopathy is one of the most important causes of blindness. The underlying mechanisms of this disease include inflammatory changes and remodeling processes of the extracellular-matrix (ECM) leading to pericyte and vascular endothelial cell ...
Chuluyan, Hector Eduardo   +3 more
core   +1 more source

Calcium Signalling in Pericytes [PDF]

open access: yesJournal of Vascular Research, 2014
Recent advances in pericyte research have contributed to our understanding of the physiology and pathophysiology of microvessels. The microvasculature consists of arteriolar and venular networks located upstream and downstream of the capillaries.
Theodor, Burdyga, Lyudmyla, Borysova
openaire   +2 more sources

The complex TIE between macrophages and angiogenesis [PDF]

open access: yes, 2020
Macrophages are primarily known as phagocytic immune cells, but they also play a role in diverse processes, such as morphogenesis, homeostasis and regeneration.
Anghelina M.   +81 more
core   +2 more sources

Improvement of Neurological Function in Rats with Ischemic Stroke by Adipose-derived Pericytes

open access: yesCell Transplantation, 2020
Pericytes possess high multipotent features and cell plasticity, and produce angiogenic and neurotrophic factors that indicate their high regenerative potential.
Vyacheslav Ogay   +15 more
doaj   +1 more source

Metabolism within the tumor microenvironment and its implication on cancer progression: an ongoing therapeutic target [PDF]

open access: yes, 2018
Since reprogramming energy metabolism is considered a new hallmark of cancer, tumor metabolism is again in the spotlight of cancer research. Many studies have been carried out and many possible therapies have been developed in the last years.
Abdel-Aziz   +431 more
core   +2 more sources

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