Results 21 to 30 of about 62,021 (301)
Sympathetic nerve-derived ATP regulates renal medullary blood flow via vasa recta pericytes [PDF]
, 2013 Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of contractile proteins. We have previously shown that exogenous ATP causes constriction of vasa
Peppiatt-Wildman, C. M. +12 more
core +1 more source
, 2019 Liver pericytes, commonly named hepatic stellate cells (HSCs), reside in the space between liver sinusoidal endothelial cells (LSECs) and hepatocytes. They display important roles in health and disease. HSCs ensure the storage of the majority of vitamin A in a healthy body, and they represent the major source of fibrotic tissue in liver disease ...
Enis, Kostallari, Vijay H, Shah
openaire +2 more sources
Pulmonary pericytes regulate lung morphogenesis [PDF]
, 2018 Blood vessels are essential for blood circulation but also control organ growth, homeostasis, and regeneration, which has been attributed to the release of paracrine signals by endothelial cells.
Susanne Adams +10 more
core +4 more sources
Pericytes in Cerebrovascular Diseases: An Emerging Therapeutic Target
Frontiers in Cellular Neuroscience, 2019 Pericytes are functional components of the neurovascular unit (NVU) that are located around the blood vessels, and their roles in the regulation of cerebral health and diseases has been reported.
Xiaojuan Su +8 more
doaj +1 more source
Endogenous brain pericytes are widely activated and contribute to mouse glioma microvasculature. [PDF]
PLoS ONE, 2015 Glioblastoma multiforme (GBM) is the most common brain tumor in adults. It presents an extremely challenging clinical problem, and treatment very frequently fails due to the infiltrative growth, facilitated by extensive angiogenesis and ...
Andreas Svensson +4 more
doaj +1 more source
Neural pericytes: A genomic archival state programmed by CHromatin topology
European Journal of Cell Biology, 2022 Accumulating evidence suggests that mural pericytes, apart from stabilizing the associated microvessels, play additional roles in regeneration of local cellular elements.
Ramin M. Farahani
doaj +1 more source
An Intact Kidney Slice Model to Investigate Vasa Recta Properties and Function in situ [PDF]
, 2012 Background: Medullary blood flow is via vasa recta capillaries, which possess contractile pericytes. In vitro studies using isolated descending vasa recta show that pericytes can constrict/dilate descending vasa recta when vasoactive substances are ...
Kennedy-Lydon, T. +10 more
core +1 more source
Brain Microvascular Pericytes—More than Bystanders in Breast Cancer Brain Metastasis
Cells, 2022 Brain tissue contains the highest number of perivascular pericytes compared to other organs. Pericytes are known to regulate brain perfusion and to play an important role within the neurovascular unit (NVU).
Danyyl Ippolitov +3 more
doaj +1 more source
Human kidney pericytes produce renin [PDF]
, 2016 Pericytes, perivascular cells embedded in the microvascular wall, are crucial for vascular homeostasis. These cells also play diverse roles in tissue development and regeneration as multi-lineage progenitors, immunomodulatory cells and as sources of ...
Kenyon, C. +15 more
core +1 more source
Primary human lung pericytes support and stabilize in-vitro perfusable microvessels. [PDF]
, 2015 The formation of blood vessels is a complex tissue-specific process that plays a pivotal role during developmental processes, in wound healing, cancer progression, fibrosis and other pathologies.
Schmid, Ralph +4 more
core +1 more source