Results 21 to 30 of about 10,316 (244)
Liver pericytes, commonly named hepatic stellate cells (HSCs), reside in the space between liver sinusoidal endothelial cells (LSECs) and hepatocytes. They display important roles in health and disease. HSCs ensure the storage of the majority of vitamin A in a healthy body, and they represent the major source of fibrotic tissue in liver disease ...
Enis, Kostallari, Vijay H, Shah
openaire +2 more sources
Renal pericytes: regulators of medullary blood flow [PDF]
Regulation of medullary blood flow (MBF) is essential in maintaining normal kidney function. Blood flow to the medulla is supplied by the descending vasa recta (DVR), which arise from the efferent arterioles of juxtamedullary glomeruli.
Peppiatt-Wildman, Claire M. +10 more
core +1 more source
Sympathetic nerve-derived ATP regulates renal medullary blood flow via vasa recta pericytes [PDF]
Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of contractile proteins. We have previously shown that exogenous ATP causes constriction of vasa
Peppiatt-Wildman, C. M. +12 more
core +1 more source
Introduction Pericytes are cells with intriguing properties that have only recently attracted the attention of numerous researchers. In the past years, their function was mainly associated with microvascular homeostasis, angiogenesis and maintenance ...
Elena Ranieri +13 more
core +1 more source
Isolation of endothelial cells, pericytes and astrocytes from mouse brain [PDF]
Primary cell isolation from the central nervous system (CNS) has allowed fundamental understanding of blood-brain barrier (BBB) properties. However, poorly described isolation techniques or suboptimal cellular purity has been a weak point of some ...
Bernard-Patrzynski, Florian +9 more
core +3 more sources
Pulmonary pericytes regulate lung morphogenesis [PDF]
Blood vessels are essential for blood circulation but also control organ growth, homeostasis, and regeneration, which has been attributed to the release of paracrine signals by endothelial cells.
Adams S. +10 more
core +3 more sources
Endogenous brain pericytes are widely activated and contribute to mouse glioma microvasculature. [PDF]
Glioblastoma multiforme (GBM) is the most common brain tumor in adults. It presents an extremely challenging clinical problem, and treatment very frequently fails due to the infiltrative growth, facilitated by extensive angiogenesis and ...
Andreas Svensson +4 more
doaj +1 more source
Neural pericytes: A genomic archival state programmed by CHromatin topology
Accumulating evidence suggests that mural pericytes, apart from stabilizing the associated microvessels, play additional roles in regeneration of local cellular elements.
Ramin M. Farahani
doaj +1 more source
Brain Microvascular Pericytes—More than Bystanders in Breast Cancer Brain Metastasis
Brain tissue contains the highest number of perivascular pericytes compared to other organs. Pericytes are known to regulate brain perfusion and to play an important role within the neurovascular unit (NVU).
Danyyl Ippolitov +3 more
doaj +1 more source
Recent evidence suggests that capillary pericytes are contractile and play a crucial role in the regulation of microcirculation. However, failure to detect components of the contractile apparatus in capillary pericytes, most notably α-smooth muscle actin
Luis Alarcon-Martinez +7 more
doaj +1 more source

