Results 21 to 30 of about 10,316 (244)

Pericytes in the Liver [PDF]

open access: yes, 2019
Liver pericytes, commonly named hepatic stellate cells (HSCs), reside in the space between liver sinusoidal endothelial cells (LSECs) and hepatocytes. They display important roles in health and disease. HSCs ensure the storage of the majority of vitamin A in a healthy body, and they represent the major source of fibrotic tissue in liver disease ...
Enis, Kostallari, Vijay H, Shah
openaire   +2 more sources

Renal pericytes: regulators of medullary blood flow [PDF]

open access: yes, 2012
Regulation of medullary blood flow (MBF) is essential in maintaining normal kidney function. Blood flow to the medulla is supplied by the descending vasa recta (DVR), which arise from the efferent arterioles of juxtamedullary glomeruli.
Peppiatt-Wildman, Claire M.   +10 more
core   +1 more source

Sympathetic nerve-derived ATP regulates renal medullary blood flow via vasa recta pericytes [PDF]

open access: yes, 2013
Pericyte cells are now known to be a novel locus of blood flow control, being able to regulate capillary diameter via their unique morphology and expression of contractile proteins. We have previously shown that exogenous ATP causes constriction of vasa
Peppiatt-Wildman, C. M.   +12 more
core   +1 more source

TLR-4 Signaling in Pericytes

open access: yes, 2021
Introduction Pericytes are cells with intriguing properties that have only recently attracted the attention of numerous researchers. In the past years, their function was mainly associated with microvascular homeostasis, angiogenesis and maintenance ...
Elena Ranieri   +13 more
core   +1 more source

Isolation of endothelial cells, pericytes and astrocytes from mouse brain [PDF]

open access: yes, 2019
Primary cell isolation from the central nervous system (CNS) has allowed fundamental understanding of blood-brain barrier (BBB) properties. However, poorly described isolation techniques or suboptimal cellular purity has been a weak point of some ...
Bernard-Patrzynski, Florian   +9 more
core   +3 more sources

Pulmonary pericytes regulate lung morphogenesis [PDF]

open access: yes, 2018
Blood vessels are essential for blood circulation but also control organ growth, homeostasis, and regeneration, which has been attributed to the release of paracrine signals by endothelial cells.
Adams S.   +10 more
core   +3 more sources

Endogenous brain pericytes are widely activated and contribute to mouse glioma microvasculature. [PDF]

open access: yesPLoS ONE, 2015
Glioblastoma multiforme (GBM) is the most common brain tumor in adults. It presents an extremely challenging clinical problem, and treatment very frequently fails due to the infiltrative growth, facilitated by extensive angiogenesis and ...
Andreas Svensson   +4 more
doaj   +1 more source

Neural pericytes: A genomic archival state programmed by CHromatin topology

open access: yesEuropean Journal of Cell Biology, 2022
Accumulating evidence suggests that mural pericytes, apart from stabilizing the associated microvessels, play additional roles in regeneration of local cellular elements.
Ramin M. Farahani
doaj   +1 more source

Brain Microvascular Pericytes—More than Bystanders in Breast Cancer Brain Metastasis

open access: yesCells, 2022
Brain tissue contains the highest number of perivascular pericytes compared to other organs. Pericytes are known to regulate brain perfusion and to play an important role within the neurovascular unit (NVU).
Danyyl Ippolitov   +3 more
doaj   +1 more source

Capillary pericytes express α-smooth muscle actin, which requires prevention of filamentous-actin depolymerization for detection

open access: yeseLife, 2018
Recent evidence suggests that capillary pericytes are contractile and play a crucial role in the regulation of microcirculation. However, failure to detect components of the contractile apparatus in capillary pericytes, most notably α-smooth muscle actin
Luis Alarcon-Martinez   +7 more
doaj   +1 more source

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