Results 11 to 20 of about 67,690 (294)
Targeting pericytes for neurovascular regeneration
Cell Communication and Signaling, 2019 Pericytes, as a key cellular part of the blood-brain barrier, play an important role in the maintenance of brain neurovascular unit. These cells participate in brain homeostasis by regulating vascular development and integrity mainly through secreting ...
Mohammad Hossein Geranmayeh +2 more
doaj +2 more sources
, 2019 Pericytes have long been known to contribute indirectly to tumour growth by regulating angiogenesis. Thus, remodelling tumour blood vessels to maintain blood supply is critical for continued tumour growth. A role for pericytes in restricting leakage of tumour cells through blood vessels has also become evident given that adequate pericyte coverage of ...
Pieterse, Z., Sinha, D., Kaur, Pritinder
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Combined Effects of Pericytes in the Tumor Microenvironment
Stem Cells International, 2015 Pericytes are multipotent perivascular cells whose involvement in vasculature development is well established. Evidences in the literature also suggest that pericytes display immune properties and that these cells may serve as an in vivo reservoir of ...
Aline Lopes Ribeiro +1 more
doaj +2 more sources
Human kidney pericytes produce renin [PDF]
, 2016 Pericytes, perivascular cells embedded in the microvascular wall, are crucial for vascular homeostasis. These cells also play diverse roles in tissue development and regeneration as multi-lineage progenitors, immunomodulatory cells and as sources of ...
Shaw, Isaac +8 more
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An investigation into murine pericyte shape change in response to inflammatory stimuli in vitro and in vivo [PDF]
, 2011 PhDLeukocyte transmigration through venular walls into the surrounding tissue is a crucial event during inflammatory responses. Despite increased understanding of the mechanisms associated with leukocyte migration through endothelial cells, little is ...
Proebstl, Doris
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Clinical and Experimental Pharmacology and Physiology, 2000 SUMMARY1. Pericytes are cells of microvessels (arterioles, capillaries and venules) that wrap around endothelial cells. They are most abundant on venules and are common on capillaries.2. The pericyte population is highly variable between different tissues and organs, probably in a manner reflecting postarteriolar hydrostatic pressures.
openaire +3 more sources
Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte-Mediated Fibrosis and Protecting Nucleus Pulposus Cells. [PDF]
Adv Sci (Weinh)The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Ma F +12 more
europepmc +2 more sources
EBF1 is expressed in pericytes and contributes to pericyte cell commitment [PDF]
Histochemistry and Cell Biology, 2021 AbstractEarly B-cell factor-1 (EBF1) is a transcription factor with an important role in cell lineage specification and commitment during the early stage of cell maturation. Originally described during B-cell maturation, EBF1 was subsequently identified as a crucial molecule for proper cell fate commitment of mesenchymal stem cells into adipocytes ...
Pagani F. +4 more
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Pericytes in the microvasculature [PDF]
Cardiovascular Research, 1996 Pericytes, also known as Rouget cells or mural cells, are associated abluminally with all vascular capillaries and post-capillary venules. Differences in pericyte morphology and distribution among vascular beds suggest tissue-specific functions. Based on their location and their complement of muscle cytoskeletal proteins, pericytes have been proposed ...
K K, Hirschi, P A, D'Amore
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Microcirculation, 2008 ABSTRACTObjectives: Cochlear pericytes are not well characterized. The aim of this study was to further advance the characterization of cochlear pericyte location and distribution, with particular focus on pericyte‐related proteins on the capillaries of the cochlear lateral wall that are functionally integral to structure, contraction, and gap junction
Xiaorui, Shi +7 more
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