Results 11 to 20 of about 88,738 (306)
EBF1 is expressed in pericytes and contributes to pericyte cell commitment [PDF]
Histochemistry and Cell Biology, 2021 AbstractEarly B-cell factor-1 (EBF1) is a transcription factor with an important role in cell lineage specification and commitment during the early stage of cell maturation. Originally described during B-cell maturation, EBF1 was subsequently identified as a crucial molecule for proper cell fate commitment of mesenchymal stem cells into adipocytes ...
Pagani F. +4 more
openaire +3 more sources
Microcirculation, 2008 ABSTRACTObjectives: Cochlear pericytes are not well characterized. The aim of this study was to further advance the characterization of cochlear pericyte location and distribution, with particular focus on pericyte‐related proteins on the capillaries of the cochlear lateral wall that are functionally integral to structure, contraction, and gap junction
Xiaorui, Shi +7 more
openaire +2 more sources
Pericyte mechanics and mechanobiology [PDF]
Journal of Cell Science, 2021 ABSTRACT Pericytes are mural cells of the microvasculature, recognized by their thin processes and protruding cell body. Pericytes wrap around endothelial cells and play a central role in regulating various endothelial functions, including angiogenesis and inflammation.
Claire A. Dessalles +2 more
openaire +3 more sources
, 2019 Liver pericytes, commonly named hepatic stellate cells (HSCs), reside in the space between liver sinusoidal endothelial cells (LSECs) and hepatocytes. They display important roles in health and disease. HSCs ensure the storage of the majority of vitamin A in a healthy body, and they represent the major source of fibrotic tissue in liver disease ...
Enis, Kostallari, Vijay H, Shah
openaire +2 more sources
Neural pericytes: A genomic archival state programmed by CHromatin topology
European Journal of Cell Biology, 2022 Accumulating evidence suggests that mural pericytes, apart from stabilizing the associated microvessels, play additional roles in regeneration of local cellular elements.
Ramin M. Farahani
doaj +1 more source
Pericytes in Cerebrovascular Diseases: An Emerging Therapeutic Target
Frontiers in Cellular Neuroscience, 2019 Pericytes are functional components of the neurovascular unit (NVU) that are located around the blood vessels, and their roles in the regulation of cerebral health and diseases has been reported.
Xiaojuan Su +8 more
doaj +1 more source
Endogenous brain pericytes are widely activated and contribute to mouse glioma microvasculature. [PDF]
PLoS ONE, 2015 Glioblastoma multiforme (GBM) is the most common brain tumor in adults. It presents an extremely challenging clinical problem, and treatment very frequently fails due to the infiltrative growth, facilitated by extensive angiogenesis and ...
Andreas Svensson +4 more
doaj +1 more source
Brain Microvascular Pericytes—More than Bystanders in Breast Cancer Brain Metastasis
Cells, 2022 Brain tissue contains the highest number of perivascular pericytes compared to other organs. Pericytes are known to regulate brain perfusion and to play an important role within the neurovascular unit (NVU).
Danyyl Ippolitov +3 more
doaj +1 more source
eLife, 2018 Recent evidence suggests that capillary pericytes are contractile and play a crucial role in the regulation of microcirculation. However, failure to detect components of the contractile apparatus in capillary pericytes, most notably α-smooth muscle actin
Luis Alarcon-Martinez +7 more
doaj +1 more source
Targeting pericytes for neurovascular regeneration
Cell Communication and Signaling, 2019 Pericytes, as a key cellular part of the blood-brain barrier, play an important role in the maintenance of brain neurovascular unit. These cells participate in brain homeostasis by regulating vascular development and integrity mainly through secreting ...
Mohammad Hossein Geranmayeh +2 more
doaj +1 more source