Results 11 to 20 of about 10,316 (244)
Targeting pericytes for neurovascular regeneration
Cell Communication and Signaling, 2019 Pericytes, as a key cellular part of the blood-brain barrier, play an important role in the maintenance of brain neurovascular unit. These cells participate in brain homeostasis by regulating vascular development and integrity mainly through secreting ...
Mohammad Hossein Geranmayeh +2 more
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, 2019 Pericytes have long been known to contribute indirectly to tumour growth by regulating angiogenesis. Thus, remodelling tumour blood vessels to maintain blood supply is critical for continued tumour growth. A role for pericytes in restricting leakage of tumour cells through blood vessels has also become evident given that adequate pericyte coverage of ...
Pieterse, Z., Sinha, D., Kaur, Pritinder
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Pflügers Archiv - European Journal of Physiology, 2013 Pericytes in the retina differ from pericytes in many other organs by their high density and their cooperative role in the neurovascular unit. Their diverse ontogeny and the fact that not one pericyte marker identifies the entire population suggest also functional plurality in the retina, including invading cells of mesenchymal origin.
Frederick, Pfister +3 more
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Pericytes and Neurovascular Function in the Healthy and Diseased Brain
Frontiers in Cellular Neuroscience, 2019 Pericytes are multi-functional cells embedded within the walls of capillaries throughout the body, including the brain. Pericytes were first identified in the 1870s, but little attention was paid to them during the following century.
Lachlan S. Brown +5 more
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Molecular mechanisms underlying therapeutic potential of pericytes
Journal of Biomedical Science, 2018 Background Pericytes are multipotent cells present in every vascularized tissue in the body. Despite the fact that they are well-known for more than a century, pericytes are still representing cells with intriguing properties.
C. Randall Harrell +5 more
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Clinical and Experimental Pharmacology and Physiology, 2000 SUMMARY1. Pericytes are cells of microvessels (arterioles, capillaries and venules) that wrap around endothelial cells. They are most abundant on venules and are common on capillaries.2. The pericyte population is highly variable between different tissues and organs, probably in a manner reflecting postarteriolar hydrostatic pressures.
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An investigation into murine pericyte shape change in response to inflammatory stimuli in vitro and in vivo [PDF]
, 2011 PhDLeukocyte transmigration through venular walls into the surrounding tissue is a crucial event during inflammatory responses. Despite increased understanding of the mechanisms associated with leukocyte migration through endothelial cells, little is ...
Proebstl, Doris
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EBF1 is expressed in pericytes and contributes to pericyte cell commitment [PDF]
Histochemistry and Cell Biology, 2021 AbstractEarly B-cell factor-1 (EBF1) is a transcription factor with an important role in cell lineage specification and commitment during the early stage of cell maturation. Originally described during B-cell maturation, EBF1 was subsequently identified as a crucial molecule for proper cell fate commitment of mesenchymal stem cells into adipocytes ...
Pagani F. +4 more
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Human kidney pericytes produce renin [PDF]
, 2016 Pericytes, perivascular cells embedded in the microvascular wall, are crucial for vascular homeostasis. These cells also play diverse roles in tissue development and regeneration as multi-lineage progenitors, immunomodulatory cells and as sources of ...
Kenyon, C. +15 more
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Microcirculation, 2008 ABSTRACTObjectives: Cochlear pericytes are not well characterized. The aim of this study was to further advance the characterization of cochlear pericyte location and distribution, with particular focus on pericyte‐related proteins on the capillaries of the cochlear lateral wall that are functionally integral to structure, contraction, and gap junction
Xiaorui, Shi +7 more
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