Results 161 to 170 of about 728,967 (344)

Improvement of EPO Transgene Detection From Polymeric Dried Blood Spots for Antidoping Application

open access: yesDrug Testing and Analysis, EarlyView.
This article presents an optimized protocol for gene doping detection. Starting from one spot DBS (20 μL), concentrated DNA was obtained and real‐time PCR parameters were adjusted for increased detection. Robust detection of 5000 copies/mL of transgene was validated for polymeric device TASSO M‐20.
Alexandre Marchand   +2 more
wiley   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff   +6 more
wiley   +1 more source

Reviews of High‐Longevity Aqueous Zinc Metal Batteries Achieved by Programmable Interface Architectures

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This review focuses on the mechanisms of Zn2+ electrodeposition and interfacial failure together with systematical artificial interphase layer design strategies from carbon materials, zincophilic alloys, to inorganic/organic compound layers, regulating ion flux and desolvation and providing guidance for programmable interface construction in aqueous ...
Bixian Chen   +12 more
wiley   +1 more source

Sustainability in Analytical Chemistry Illustrated by Pharmaceutical Nitrosamine Testing

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT Following the valsartan scandal in 2018, the testing of drug substances and drug products for N‐nitrosamines has become a critical and mandatory quality control measure. The European Pharmacopoeia chapter 2.5.42 currently describes three analytical methods for this purpose: HPLC–MS/MS, GC–MS, and GC–MS/MS.
Felix Bredendiek   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy