Results 221 to 230 of about 721,706 (356)

Improving Interpretation Consistency of Serum Capillary Electrophoresis by Development of Quantitative Graphic Indexes. [PDF]

open access: yesInt J Mol Sci
Yu JR   +9 more
europepmc   +1 more source

Characterization of the Specific Binding Between Aptamers and Cytochrome c With Pressure‐Assisted Capillary Electrophoresis Frontal Analysis

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT Cytochrome c (cyt c) is a heme protein located in the mitochondrial intermembrane space. Because the release of cyt c is a highly specific event in apoptotic signaling, it can serve as an apoptosis‐related marker. To date, three frequently used aptamers for cyt c (Apt40, Apt61, and Apt76) have been selected and applied in the field of sensing.
Shuanghao Wang   +4 more
wiley   +1 more source

The Hidden Influence: Impacts of Residual Dimethylformamide in NDSB‐211 on icIEF Separation for Monoclonal Antibodies

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT Monoclonal antibodies (mAbs) present analytical challenges due to their inherent heterogeneity and susceptibility to post‐translational modifications (PTMs) during production and storage. Monitoring of charge heterogeneity profiles by imaged capillary isoelectric focusing (icIEF) has been aided by the use of non‐detergent sulfobetaines (NDSBs),
Delaney Doran   +5 more
wiley   +1 more source

Capillary‐Based Physicochemical Characterization of Lipid Nanoparticles

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) are widely used for the delivery of nucleic acid (NAs), most notably in gene therapy and messenger ribonucleic acid (mRNA)‐based vaccines. Understanding their physicochemical properties is essential, yet current analytical approaches often fall short in capturing their complexity.
Evrim Ümit Kuzucu   +3 more
wiley   +1 more source

Miniaturized nanoelectrospray interface for coupling capillary electrophoresis with mass spectrometry detection. [PDF]

open access: yesElectrophoresis
Václavek T   +5 more
europepmc   +1 more source

Towards an Analytical Procedure Control Strategy for the Capillary Zone Electrophoresis Method for Monoclonal Antibodies: Alternatives for ε‐Aminocaproic Acid and Triethylenetetramine

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT The ICH guideline Q14 on analytical procedure development underlines the importance of science and risk‐based methods for the evaluation of the quality of medicines. Ultimately, a pharmaceutical company, the sponsor, is responsible that the analytical method is fit‐for‐purpose during routine use throughout its lifecycle. Part of the analytical
Joanne Baxter   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy