Results 51 to 60 of about 721,706 (356)

Chemoselective Characterization of New Extracellular Matrix Deposition in Bioengineered Tumor Tissues

Advanced Materials, EarlyView.
Understanding the bi‐directional crosstalk between cells and their surrounding extracellular matrix (ECM) is critical for tissue engineering. This study presents a chemoselective strategy for proteomic profiling of newly deposited ECM from resident cells.
Zihan Ling, Burke Niego, Qingyang Li, Dhruv Bhattaram, Vanessa Serna Villa, Michael Hu, Zhuowei Gong, Lloyd M. Smith, Brian L. Frey, Xi Ren   +9 more
wiley   +1 more source

Light‐Activated Micromotors in Air Propelled by Thermal Convection

Advanced Materials, EarlyView.
Near‐infrared‐driven micromotors in air can overcome gravity and generate convective motion by a light‐induced thermal mechanism driven by a temperature gradient in the air caused by the interaction of the gold nanoparticles present on the surface of ZnO and NIR irradiation.
Pedro Mena‐Giraldo, Gabrielle A. Mandl, Victor Quezada‐Novoa, Camilo Garcia‐Henao, Nicolas Bondon, Melanie Jane Hazlett, John A. Capobianco   +6 more
wiley   +1 more source

Nanostructured Protein Surfaces Inspired by Spider Silk

Advanced Materials, EarlyView.
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley   +1 more source

Responsive Polyelectrolyte Brushes in Applications: Functions, Stimuli, and Design Considerations

Advanced Materials, EarlyView.
With advances in the synthesis of polyelectrolyte brushes, these coatings of surface‐grafted chains find uses in an increasing number of applications. This review summarizes three core aspects of these brushes: how they introduce functionality to surfaces; how external stimuli influence their properties; and what practical considerations should be ...
Leon A. Smook, Andreas Dahlin, Karin Schroën, Sissi de Beer   +3 more
wiley   +1 more source

Biocompatibility and Long‐Term Stability of DNA‐Based Organic Mixed Conductors for Bioelectronics

Advanced Materials Interfaces, EarlyView.
The biocompatibility and long‐term stability of DNA‐based mixed ionic‐electronic conductors are investigated. In vitro cytotoxicity and cell viability are assessed using flow cytometry assay on primary mouse fibroblasts cultures. The biocomposites are integrated into organic electrochemical transistors (OECTs) to determine the stability of their ...
Sarka Hradilova, Katharina Matura, Munise Cobet, Ariana Opletalova, Yolanda Salinas, Niyazi Serdar Sariciftci, Serpil Tekoglu, Katerina Polakova   +7 more
wiley   +1 more source

Physical Adsorption‐Driven Assembly of Au‐Locked Nucleic Acid (LNA) Probes on MoS2 Nanosheets for SERS‐Based Detection of microRNAs (miRNAs)

Advanced Materials Interfaces, EarlyView.
The Au‐LNA Raman probe, composed of gold nanoparticles (AuNPs), thiol functional group, and Cy3 modified LNAs, synthesized after hybridization of LNA and miR‐210‐3p target, is integrated into the MoS2@Au composite. The integration of the nanocomposite is formed by physical adsorption of Au‐LNA nanohybrid with MoS2. Characterization confirms morphology,
Faith Mokobi Zablon, Md. Arifur Rahman Khan, Tetyana Ignatova, Kristen Dellinger, Shyam Aravamudhan   +4 more
wiley   +1 more source

Highly Sensitive Detection of Human Serum Albumin Biomarker Using a Molecularly Imprinted Polymer‐Based Electrochemical Capacitance Sensor

Advanced Sensor Research, EarlyView.
An electrosynthesized protein‐imprinted polymer (poly(azo‐BBY)) enables probe‐free, real‐capacitance detection of human serum albumin at 0.02 ng mL−1 within a 0.25–3.0 ng mL−1 window. The device uses a redox‐mediator‐free architecture and maintains selectivity against common interferents, illustrating a simple, scalable route to high‐sensitivity ...
Heitor F. Trevizan, Pedro C. M. Pizzol, André Olean‐Oliveira, Patrícia Monteiro Seraphim, Marcos F. S. Teixeira   +4 more
wiley   +1 more source

Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity

Advanced Science, EarlyView.
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong, Lin‐Lin Hu, Ling Jiang, Pei‐Xia Shi, Shuang Zhang, Yuan Zhao, Bing‐Qiao Wang, Xiao‐Feng Cheng, Cheng‐Kang He, Sen Lin, Yue Dai, Zhao‐You Meng, Chen‐Hao Zhao, Bao‐Liang Sun, Qi Xie, Fang‐Fei Li, Qing‐Wu Yang   +16 more
wiley   +1 more source

Two-Dimensional Capillary Electrophoresis with On-Line Sample Preparation and Cyclodextrin Separation Environment for Direct Determination of Serotonin in Human Urine

Molecules, 2017
An advanced two-dimensional capillary electrophoresis method, based on on-line combination of capillary isotachophoresis and capillary zone electrophoresis with cyclodextrin additive in background electrolyte, was developed for effective determination of
Juraj Piešťanský, Katarína Maráková, Peter Mikuš   +2 more
doaj   +1 more source

Okanin Suppresses the Growth of Colorectal Cancer Cells by Targeting at Peroxiredoxin 5

Advanced Science, EarlyView.
Okanin suppresses colorectal cancer growth by directly targeting PRDX5. This natural compound selectively binds peroxiredoxin 5 (PRDX5), inhibiting its activity and inducing WSB1‐mediated degradation. PRDX5 loss elevates ROS, suppresses GPX4 via SIAH2, and further triggers cell death (apoptosis and ferroptosis).
Ji Zhong Zhao, Yuan Fei Li, Fu Kang Yuan, Meng Lu Zhao, Ya Wen Han, Jia Xin Wang, Qi Yang, Han Ying Ye, Yu Cheng Lu, Shao Chin Lee   +9 more
wiley   +1 more source