Results 51 to 60 of about 242,861 (350)

FGF14 GAA Intronic Expansion in Unsolved Adult‐Onset Ataxia in the Care4Rare Canada Consortium

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Spinocerebellar ataxias (SCA) represent a clinically and genetically heterogeneous group of progressive neurodegenerative diseases with prominent cerebellar atrophy. Recently, a novel pathogenic repeat expansion in intron 1 of FGF14 was identified, causing adult‐onset SCA (SCA27B). We aimed to determine the proportion
Alexanne Cuillerier, Giulia F. Del Gobbo, Layla Mackay, Erika Wall, Madeline Couse, Laura M. McDonell, Mireille Cloutier, Matt C. Danzi, Jodi Warman‐Chardon, Pierre R. Bourque, Oksana Suchowersky, Alan Mears, Luke Seldenthuis, Wendy Mears, Laura Larrigan, Alexandre White‐Brown, Gerald Pfeffer, Dennis E. Bulman, David Dyment, Care4Rare Canada Consortium, Kym M. Boycott   +20 more
wiley   +1 more source

Kapilarna elektroforeza u farmaciji [PDF]

, 2010
Capillary electrophoresis is a new separation technique. It is an analytical technique that usually complements or replaces high performance liquid chromatography.
Damić, Miranda, Nigović, Biljana
core   +1 more source

Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib

ACR Open Rheumatology, EarlyView.
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi, Ennio Giulio Favalli, Gabriella Maioli, Elena Agape, Marzia Rossato, Matteo Paini, Adriana Severino, Barbara Vigone, Martina Biggioggero, Elena Trombetta, Roberto Caporali, Lorenzo Beretta   +11 more
wiley   +1 more source

Microchip Capillary Electrophoresis [PDF]

, 2014
For the study of neuromodulation in Cancer borealis we have designed a microfluidic device to separate and detect bioamine concentrations with a high temporal resolution.
Hardy, Scott, Schull, Daniel, Vinopal, Mark   +2 more
core   +1 more source

Fibrous Pb(II)‐Based Coordination Polymer Operable as a Photocatalyst and Electrocatalyst for High‐Rate, Selective CO2‐to‐Formate Conversion

Advanced Functional Materials, EarlyView.
A coordination polymer [Pb(tadt)]n prepared by a microwave‐assisted solvothermal method selectively reduces CO2 into formate under visible light with a high apparent quantum yield of ≈25% at 400 nm. It can function as a pre‐catalyst, along with conductive Ketjen Black, to form an active PbCO3/Pb3(CO3)2(OH)2 mixture that exhibits a high Faradaic ...
Chomponoot Suppaso, Ryosuke Nakazato, Shoko Nakahata, Yoshinobu Kamakura, Fumitaka Ishiwari, Akinori Saeki, Daisuke Tanaka, Kazuhide Kamiya, Kazuhiko Maeda   +8 more
wiley   +1 more source

Recent advances in screening of enzymes inhibitors based on capillary electrophoresis

Journal of Pharmaceutical Analysis, 2018
Capillary electrophoresis with many advantages plays an important role in pharmaceutical analysis and drug screening. This review gives an overview on the recent advances in the developments and applications of capillary electrophoresis in the field of ...
Mengxia Cheng, Zilin Chen
doaj  

Patterned Assembly of Transition Metal Dichalcogenide/Graphene Heterostructures via Direct Laser Writing

Advanced Functional Materials, EarlyView.
The fabrication of patterned transition metal dichalcogenide (TMD)/graphene heterostructures via direct laser writing reveals new interface chemistry and enables efficient, customizable assembly. Selective laser irradiation of functionalized TMD/graphene triggers localized reactions, forming chemically modified interfaces.
Xin Chen, Stefan Wolff, Sofiia Zuieva, Robert Schusterbauer, Rida Shaikh, Christian E. Halbig, Anton Habel, Roland Gillen, Kathrin C. Knirsch, Ievgen Donskyi, Siegfried Eigler, Janina Maultzsch, Andreas Hirsch   +12 more
wiley   +1 more source

Hybrid integrated platform of PDMS microfluidics and silica capillary for effective CE and ESI-MS coupling [PDF]

, 2009
We present an effective hybrid integration of PDMS microfluidic devices and fused silica capillaries. These hybrid microfluidic integrated PDMS and silica capillary (iPSC) modules exhibit a novel architecture and method for leakage free CE sample ...
Dimov, Ivan Krastev, Ducrée, Jens, Lee, Luke P., Riaz, Asif   +3 more
core   +1 more source

Capillary Electrophoresis in Bioanalysis [PDF]

Analytical Chemistry, 2008
For the period January 2006 to December 2007, Web of Science reports ∼4800 hits on capillary electrophoresis (CE) including 410 reviews. Because of the prominence of CE techniques in bioanalysis, we decided make them the focus of this review and selected 200 hundred papers representing advances in this field.
Edgar A. Arriaga, Joseph B. Katzenmeyer, Vratislav Kostal   +2 more
openaire   +3 more sources

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source