Results 81 to 90 of about 721,706 (356)

Sistemas interfaceados de análise por injeção em fluxo e eletroforese capilar (FIA - CE): desafios, aplicações e perspectivas

Química Nova, 2002
A review about the state-of-the-art of flow injection analysis (FIA) -- capillary electrophoresis (CE) systems is presented. The basic principles of flow injection and capillary electrophoresis are briefly revised.
Miranda Carlos E. S., Carrilho Emanuel, Gervasio Ana Paula, Giné Maria Fernanda   +3 more
doaj  

Capillary Electrophoresis with Diode Array Detection for the Quantification of Triptorelin and Lanreotide in Pharmaceutical Quality Control: Development, Validation, Greenness and Practicality Evaluation

European Pharmaceutical Journal
Capillary electrophoresis (CE)-based methods hold significant potential for routine use in pharmaceutical quality control (QC) laboratories. Therefore, this study aimed to develop a novel, green, and simple hydrodynamically open-system capillary zone ...
Stefanik O., Mikus P., Piestansky J.
doaj   +1 more source

Equipment for multifunctional use in high-performance capillary electrophoresis [PDF]

, 1993
Theo P.E.M. Veŕheggen, F.M. Everaerts
openalex   +1 more source

CAPILLARY ELECTROPHORESIS

, 2023
Capillary electrophoresis [CE] is an analytical technique performed in a thin diameter glass tube that separate ions based on their electrophoretic mobility with help of an applied voltage. CE plays an ideal role in the analysis of highly polar charged analytes, analysis of both basic, clinical pharmaceutical, in the analysis and characterization of ...
openaire   +1 more source

ZDHHC12 Palmitoylates HDAC8 to Promote the Progression of Hepatocellular Carcinoma Associated with a Diet High in Saturated Fatty Acids

Advanced Science, EarlyView.
This study identifies ZDHHC12 as a critical mediator of PA‐induced HCC progression. Mechanistically, PA upregulates ZDHHC12 expression through SMARCA4 activation, leading to HDAC8 palmitoylation at Cys244 which blocks HSC70‐mediated lysosomal degradation of HDAC8, thereby promoting HCC development. These findings provide novel mechanistic insights into
Xin Jin, Yulong Hong, Yongqi Zhao, Wensheng Shi, Ruilin Liu, Xinyu You, Chong Yang, Yu Zhang   +7 more
wiley   +1 more source

Application of the Principles of Green Chemistry for the Development of a New and Sensitive Method for Analysis of Ertapenem Sodium by Capillary Electrophoresis

International Journal of Analytical Chemistry, 2019
An innovative method is validated for the analysis of ertapenem sodium by capillary electrophoresis using potassium phosphate buffer 10 mM pH 7 and 15 kV voltage, in the concentration range of 70 to 120 μg mL−1.
Tahisa Marcela Pedroso, Ann Van Schepdael, Hérida Regina Nunes Salgado   +2 more
doaj   +1 more source

Restoring NK Cell Cytotoxicity Post‐Cryopreservation via Synthetic Cells

Advanced Science, EarlyView.
In this study, it is shown that 1‐day co‐culture with activated T cells or IL‐2‐presenting synthetic cells significantly enhances NK cell motility and cytotoxicity in 2D and 3D. Notably, synthetic cells restore the impaired cytotoxic function of cryopreserved NK and CAR‐NK cells in 3D.
Xiangda Zhou, Sijia Zhang, Wenjuan Yang, Susanne Gonder, Zeinab Sadjadi, Nils Piernitzki, Alina Moter, Shulagna Sharma, Anne Largeot, Nadja Küchler, Lea Kaschek, Gertrud Schäfer, Eva C. Schwarz, Hermann Eichler, Evelyn Ullrich, Heiko Rieger, Oskar Staufer, Jérôme Paggetti, Etienne Moussay, Markus Hoth, Bin Qu   +20 more
wiley   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

Inverse Shifting-PCR Modified by Capillary Electrophoresis for Detecting F8 int22h and int1h Inversions in Severe Hemophilia A Patients and Probable Carriers

Life
Globally, intron 22 inversions (Inv22s) of the factor VIII gene (F8) are the most frequent pathogenic variants and account for 45–50% of severe hemophilia A (SHA) cases, while intron 1 inversion (Inv1) explains 1–5% of SHA cases.
Rosa Michel Martínez-Contreras, Silvia Sofía García-López, Hilda Luna-Záizar, Ana Rebeca Jaloma-Cruz   +3 more
doaj   +1 more source

Polymerase-chain reaction: analysis of DNA/DNA hybridization by capillary electrophoresis [PDF]

, 1993
Nicoletta Bianchi, Carlo Mischiati, G Feriotto, Roberto Gambari   +3 more
openalex   +1 more source