Results 1 to 10 of about 6,067 (189)

Caprin-1 influences autophagy-induced tumor growth and immune modulation in pancreatic cancer [PDF]

Journal of Translational Medicine, 2023
Background Pancreatic ductal adenocarcinoma (PDAC) is characterized by rapid progression and poor prognosis. Understanding the genetic mechanisms that affect cancer properties and reprogram tumor immune microenvironment will develop new strategies to ...
Wenbo Yang, Hongze Chen, Guanqun Li, Tao Zhang, Yuhang Sui, Liwei Liu, Jisheng Hu, Gang Wang, Hua Chen, Yongwei Wang, Xina Li, Hongtao Tan, Rui Kong, Bei Sun, Le Li   +14 more
doaj   +2 more sources

RNA binding protein Caprin-2 is a pivotal regulator of the central osmotic defense response [PDF]

eLife, 2015
In response to an osmotic challenge, the synthesis of the antidiuretic hormone arginine vasopressin (AVP) increases in the hypothalamus, and this is accompanied by extension of the 3′ poly(A) tail of the AVP mRNA, and the up-regulation of the expression ...
Agnieszka Konopacka, Mingkwan Greenwood, Su-Yi Loh, Julian Paton, David Murphy   +4 more
doaj   +5 more sources

Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH [PDF]

Open Biology, 2023
G3BP is the central node within stress-induced protein–RNA interaction networks known as stress granules (SGs). The SG-associated proteins Caprin-1 and USP10 bind mutually exclusively to the NTF2 domain of G3BP1, promoting and inhibiting SG formation ...
Tim Schulte, Marc D. Panas, Xiao Han, Lucy Williams, Nancy Kedersha, Jonas Simon Fleck, Timothy J. C. Tan, Xaquin Castro Dopico, Anders Olsson, Ainhoa Moliner Morro, Leo Hanke, Johan Nilvebrant, Kim Anh Giang, Per-Åke Nygren, Paul Anderson, Adnane Achour, Gerald M. McInerney   +16 more
doaj   +2 more sources

Caprin-1 plays a role in cell proliferation and Warburg metabolism of esophageal carcinoma by regulating METTL3 and WTAP [PDF]

Journal of Translational Medicine, 2023
Background Cytoplasmic activation/proliferation-associated protein-1 (Caprin-1) is implicated in cancer cell proliferation and tumorigenesis; however, its role in the development of esophageal carcinoma (ESCA) has not been examined.
Yan Gao, Lingling Yuan, Changbin Ke, Zhijun Pei, Xiaobo Liu, Ruimin Wu, Xueyan Kui, Yanmin Zhang   +7 more
doaj   +2 more sources

β-propeller protein-associated neurodegeneration protein WDR45 regulates stress granule disassembly via phase separation with Caprin-1 [PDF]

Nature Communications
β-propeller protein-associated neurodegeneration (BPAN) is a rare X-linked neurodegenerative disorder caused by mutations in the WDR45 gene, yet its molecular mechanisms remain poorly understood.
Yin Li, Jie Fang, Yuqi Ding, Xilong Zhang, Ying Liu, Wanting Qiu, He Xu, Yunzhe Kang, Jiayu Chen, Yanyan Gao, Yan G. Zhao, Peiguo Yang, Bo Wang, Wenmin Tian, Yang Chen, Wenjian Bi, Peipei Zhang   +16 more
doaj   +2 more sources

Radiopharmaceutical application of TRK-950, an anti-CAPRIN-1 therapeutic antibody [PDF]

Journal of Cancer Research and Clinical Oncology
Purpose Tumor imaging or therapy using cancer specific carriers combined with a radioisotope has huge potential. In radiopharmaceutical development, it is important to ensure target specificity and minimal binding to normal tissues for both tumor ...
Yuki Majima, David Kryza, Mitsuaki Sanada, Jacqueline Sidi-Boumedine, Patrick Mehlen, Benjamin Gibert, Jean-Yves Blay, Fumiyoshi Okano   +7 more
doaj   +2 more sources

Productivité des caprins dans les systèmes de production agricole du Delta du fleuve Sénégal [PDF]

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1996
A travers l'analyse de la productivité, les auteurs présentent les principaux paramètres zootechniques de cheptel caprin du Delta du fleuve Sénégal, et les comparent aux références disponibles pour la même et quelques autres grandes zones agro ...
Jean-François Tourrand, Etienne Landais
doaj   +3 more sources

Can CAPRIN-1 Be Responsible for the Recurrence Potential of Odontogenic Keratocysts? [PDF]

eJournal of Oral Maxillofacial Research
Objectives: The purpose of this retrospective study is to compare dentigerous cysts and odontogenic keratocysts for cytoplasmic activation/proliferation - associated protein-1 antibodies via immunohistochemical staining to obtain a new perspective about ...
Nelli Yildirimyan, Mehmet Ali Altay, İrem Hicran Özbudak   +2 more
doaj   +2 more sources

Mio-pliocene faunal exchanges and african biogeography: the record of fossil bovids. [PDF]

PLoS ONE, 2011
The development of the Ethiopian biogeographic realm since the late Miocene is here explored with the presentation and review of fossil evidence from eastern Africa. Prostrepsiceros cf.
Faysal Bibi
doaj   +1 more source

Prosocial Behavior in Preschoolers: Effects of Early Socialization Experiences With Peers

Frontiers in Psychology, 2022
Over the last decades, many studies had focused on the psychological outcomes of children who have received early socialization outside of the family context, highlighting that the daycare experience can both positively and negatively influence the child’
Nicoletta Salerni, Claudia Caprin
doaj   +1 more source