Results 11 to 20 of about 7,534 (234)

MicroRNA-181a Functions as an Oncogene in Gastric Cancer by Targeting Caprin-1

Frontiers in Pharmacology, 2019
MicroRNA-181a (miRNA-181a) is a multifaceted miRNA implicated in various cellular processes, particularly in cell fate determination and cellular invasion.
Qiang Lu, Yanchun Chen, Yanchun Chen, Dan Sun, Shukun Wang, Kang Ding, Meiyi Liu, Yan Zhang, Yujuan Miao, Huancai Liu, Fenghua Zhou, Fenghua Zhou   +11 more
doaj   +2 more sources

Expression and tumor-promoting effects of caprin-1 in human glioma

Glioma, 2018
Background: Cytoplasmic activation/proliferation-associated protein-1 (caprin-1) is a newly discovered RNA-binding protein and is now recognized as one of the putative oncogenes.
Li Zhang, Hui Gui, Xiang-Jun Tang, Zhuo-Shun Yang, Dan-Dan Zou, Jun-Ti Lu, Li-Dong Yan, Long-Jun Dai, Jie Luo, Bin Wang   +9 more
doaj   +2 more sources

Elevage caprin en Afrique de l’Ouest : une synthèse

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2016
L’Afrique de l’Ouest, avec 37,2 % du cheptel caprin continental, est l’un des principaux bassins d’élevage de cette espèce au rôle socio-économique parti­culièrement important.
Ayao Missohou, Grégoire Nahimana, Simplice Bosco Ayssiwede, Mbacké Sembene   +3 more
doaj   +2 more sources

Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950. [PDF]

Cancer Res Commun, 2023
Specific targets for cancer treatment are highly desirable, but still remain to be discovered. While previous reports suggested that CAPRIN-1 localizes in the cytoplasm, here we now show that part of this molecule is strongly expressed on the cell ...
Okano F, Saito T, Minamida Y, Kobayashi S, Ido T, Miyauchi Y, Wasai U, Akazawa D, Kume M, Ishibashi M, Jiang K, Aicher A, Heeschen C, Yonehara T.   +13 more
europepmc   +2 more sources

circIPO7 dissociates caprin-1 from ribosomes and inhibits gastric cancer cell proliferation by suppressing EGFR and mTOR. [PDF]

Oncogene, 2023
Circular RNA (circRNA) is a novel RNA molecule characterized by covalently closed loop structure. Since its discovery, researchers have shown that circRNA is not “splicing noise” but a participant of various pathophysiological processes through unique ...
Liu J, Niu L, Hao J, Yao Y, Yan M, Li H.
europepmc   +2 more sources

Yin and yang regulation of stress granules by Caprin-1. [PDF]

Proc Natl Acad Sci U S A, 2022
Significance Stress granules (SGs) are membraneless organelles regulating many vital biochemical processes. G3BP1 plays a critical role in regulating SG dynamics through its interaction with Caprin-1 and USP10.
Song D, Kuang L, Yang L, Wang L, Li H, Li X, Zhu Z, Shi C, Zhu H, Gong W.   +9 more
europepmc   +2 more sources

Fission yeast Caprin protein is required for efficient heterochromatin establishment. [PDF]

PLoS Genet
Heterochromatin is a key feature of eukaryotic genomes that serves important regulatory and structural roles in regions such as centromeres. In fission yeast, maintenance of existing heterochromatic domains relies on positive feedback loops involving ...
Zhang H, Kapitonova E, Orrego A, Spanos C, Strachan J, Bayne EH.   +5 more
europepmc   +3 more sources

Structural insights into the Caprin-2 HR1 domain in canonical Wnt signaling. [PDF]

J Biol Chem
Su C, Zhong Y, Zhou Z, Li Y, Jia Y, Xie S, Zhao J, Miao H, Luo H, Li Z, Shi Z, Li L, Song X.   +12 more
europepmc   +2 more sources

Macrophage polarization-associated lnc-Ma301 interacts with caprin-1 to inhibit hepatocellular carcinoma metastasis through the Akt/Erk1 pathway

Cancer Cell International, 2021
Background Epithelial–mesenchymal transition (EMT) promotes migration, invasion, and metastasis of hepatocellular carcinoma (HCC) cells. The molecular mechanisms behind EMT and metastasis in HCC remain unclear.
Hong-lin Luo, Tao Luo, Jun-jie Liu, Fei-Xiang Wu, T. Bai, C. Ou, Jie Chen, Lequn Li, J. Zhong   +8 more
semanticscholar   +2 more sources

Ingestion alimentaire de caprins sur pâturages de hautes montagnes dans le Nord du Maroc

African and Mediterranean Agricultural Journal - Al Awamia, 2022
L’étude a été effectuée dans trois sites montagneux (Bouhalla, Chrafat et Kalaâ) de la région de Chefchaouen. Elle a concerné une population caprine locale conduite sur pacages de hautes montagnes.
Mohamed Acherkouk, Mohammed Ayadi, Asma Al Gharad   +2 more
doaj   +1 more source