RNA binding protein Caprin-2 is a pivotal regulator of the central osmotic defense response [PDF]
eLife, 2015 In response to an osmotic challenge, the synthesis of the antidiuretic hormone arginine vasopressin (AVP) increases in the hypothalamus, and this is accompanied by extension of the 3′ poly(A) tail of the AVP mRNA, and the up-regulation of the expression ...
Agnieszka Konopacka +4 more
doaj +5 more sources
Productivité des caprins dans les systèmes de production agricole du Delta du fleuve Sénégal [PDF]
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1996 A travers l'analyse de la productivité, les auteurs présentent les principaux paramètres zootechniques de cheptel caprin du Delta du fleuve Sénégal, et les comparent aux références disponibles pour la même et quelques autres grandes zones agro ...
Jean-François Tourrand, Etienne Landais
doaj +3 more sources
Drug-induced stress granule formation protects sensory hair cells in mouse cochlear explants during ototoxicity [PDF]
, 2019 Stress granules regulate RNA translation during cellular stress, a mechanism that is generally presumed to be protective, since stress granule dysregulation caused by mutation or ageing is associated with neurodegenerative disease.
Dawson, Sally J. +6 more
core +2 more sources
Chemoimmunotherapy in Advanced, PD-1 Refractory Cutaneous Squamous Cell Carcinoma: Insights From Two Immunocompromised Patient Cases. [PDF]
Case Rep Oncol MedCutaneous squamous cell carcinoma (cSCC) is one of the most prevalent malignancies worldwide, and a subset of patients, particularly immunocompromised individuals, will face heightened risks of metastasis and mortality. This report examines two cases of immunocompromised patients treated with a combination of platinum‐ and taxane‐based chemotherapy ...
Rahimi G, In GK.
europepmc +2 more sources
Expression and tumor-promoting effects of caprin-1 in human glioma
Glioma, 2018 Background: Cytoplasmic activation/proliferation-associated protein-1 (caprin-1) is a newly discovered RNA-binding protein and is now recognized as one of the putative oncogenes.
Li Zhang +9 more
doaj +1 more source
Caprin-1, a novel Cyr61-interacting protein, promotes osteosarcoma tumor growth and lung metastasis in mice [PDF]
, 2013 Osteosarcoma (OS) is the most common primary bone malignancy in children and adolescents. More than 30% of patients develop lung metastasis, which is the leading cause of mortality.
Aemisegger, Caroline +10 more
core +1 more source
Distinct structural features of caprin-1 mediate its interaction with G3BP-1 and its induction of phosphorylation of eukaryotic translation initiation factor 2alpha, entry to cytoplasmic stress granules, and selective interaction with a subset of mRNAs [PDF]
, 2007 Caprin-1 is a ubiquitously expressed, well-conserved cytoplasmic phosphoprotein that is needed for normal progression through the G(1)-S phase of the cell cycle and occurs in postsynaptic granules in dendrites of neurons.
Solomon, Samuel +6 more
core +1 more source
Cellular senescence: A potential mode of circular RNAs regulating prostate cancer
MedComm – Oncology, Volume 2, Issue 4, December 2023., 2023 Cellular senescence (CS) and circular RNAs (circRNAs) have been shown to have important roles in prostate cancer (PCa) tumorigenesis and progression. circRNAs can exert diverse functions in regulating CS through various pathways. CS affects PCa mainly via senescence‐associated secretory phenotype (SASP) while treatment against PCa induces cellular ...
Yunpeng Li +7 more
wiley +1 more source
Overexpression of microRNA-16 declines cellular growth, proliferation and induces apoptosis in human breast cancer cells [PDF]
, 2015 MicroRNAs (miRNA) are a large family of small single-stranded RNA molecules found in all multicellular organisms. Early studies have been shown that miRNA are involved in cancer development and progression, and this role can be done by working as an ...
Hafizi, M. +8 more
core +2 more sources
MicroRNA-181a Functions as an Oncogene in Gastric Cancer by Targeting Caprin-1
Frontiers in Pharmacology, 2019 MicroRNA-181a (miRNA-181a) is a multifaceted miRNA implicated in various cellular processes, particularly in cell fate determination and cellular invasion.
Qiang Lu +11 more
doaj +1 more source