Results 31 to 40 of about 7,534 (234)

Caprin-1, a novel Cyr61-interacting protein, promotes osteosarcoma tumor growth and lung metastasis in mice [PDF]

, 2013
Osteosarcoma (OS) is the most common primary bone malignancy in children and adolescents. More than 30% of patients develop lung metastasis, which is the leading cause of mortality.
Aemisegger, Caroline, Arlt, Matthias J E, Bertz, Josefine, Born, Walter, Fuchs, Bruno, Hess, Daniel, Husmann, Knut, Langsam, Bettina, Muff, Roman, Sabile, Adam A, Ziegler, Urs   +10 more
core   +1 more source

Regulation of ribonucleoprotein condensates by RNase L during viral infection

WIREs RNA, Volume 14, Issue 4, July/August 2023., 2023
RNase L‐mediated mRNA decay inhibits stress granule assembly and promotes the assembly of RNase L‐dependent bodies. Abstract In response to viral infection, mammalian cells activate several innate immune pathways to antagonize viral gene expression. Upon recognition of viral double‐stranded RNA, protein kinase R (PKR) phosphorylates the alpha subunit ...
James M. Burke
wiley   +1 more source

Recent Cutting-Edge Technologies for the Delivery of Peptide Nucleic Acid. [PDF]

Chemistry
This review provides an overview of PNA cellular delivery methods, starting with traditional peptide‐based systems and progressing to advanced approaches using nanoparticles, liposomes, and calixarene. It highlights how these innovative strategies have opened the way for more effective and efficient PNA delivery, ultimately enhancing the potential for ...
Avitabile C, Cerasa MT, D'Aniello A, Saviano M, Moccia M.   +4 more
europepmc   +2 more sources

Overexpression of microRNA-16 declines cellular growth, proliferation and induces apoptosis in human breast cancer cells [PDF]

, 2015
MicroRNAs (miRNA) are a large family of small single-stranded RNA molecules found in all multicellular organisms. Early studies have been shown that miRNA are involved in cancer development and progression, and this role can be done by working as an ...
Hafizi, M., kouhkan, F., Mobarra, N., Movahed, M., Rad, S.M.A.H., Shafiee, A., Soleimani, M., Soufi-zomorod, M., Tasharrofi, N.   +8 more
core   +2 more sources

Histone Demethylase UTX Suppresses Tumor Cell Proliferation by Regulating Stress Granules. [PDF]

Adv Sci (Weinh)
These findings indicate that cytoplasmic UTX forms puncta and co‐localizes in stress granules (SGs) upon various stresses. UTX TPR‐domain‐dependently and demethylase‐activity‐independently destabilize SGs by binding G3BP1, the SG hub protein, to disrupt SG network, thus affects tumorigenesis.
Liu X, Liu X, Xue M, Xiao Y, Chen Y, Qiu R, Wu D, Zhou Y, Wang J, Yuan Y, Yu L, Shi T, Li Y, Su H, Chen H, Liu Y, Huang K, Zheng L.   +17 more
europepmc   +2 more sources

Dissection of virus-host cell interactions in the early response to infection [PDF]

, 2014
Stress granules (SG) are dynamic RNA/protein assemblies in the cytoplasm of the cell, formed under conditions of oxidative stress, heat shock or viral infections.
Panas, Marc D.
core   +1 more source

Caprine Arthritis-Encephalitis Virus Infection of Caprine Monocytes

Journal of General Virology, 1982
Summary Monocyte-enriched cultures of goat peripheral blood leukocytes were exposed to caprine arthritis-encephalitis virus (CAEV) at an m.o.i. of 8 TCID50 per cell as measured in goat synovial membrane cell cultures. At the time of infection, 90% of the adherent cells displayed characteristic macrophage markers of phagocytic activity and cytoplasmic ...
P, Klevjer-Anderson, L W, Anderson
openaire   +2 more sources

Caprin-1 promotes HepG2 cell proliferation, invasion and migration and is associated with poor prognosis in patients with liver cancer

Oncology Letters, 2020
The present study aimed to investigate the role of caprin-1 in liver cancer and its association with the clinicopathological features and prognosis of liver cancer, as well as the underlying mechanism of caprin-1 function. Caprin-1 expression levels in a
Xinmin Guo, Fang-Fang Zhu, Liwen Pan, Jia-Lin Chen, Jichuang Lai, Hong-Xia Wu, J. Shu   +6 more
semanticscholar   +1 more source

Intérêt fourrager de Calliandra calothyrsus en altitude à la Réunion

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1996
L'étude consiste à évaluer l'intérêt fourrager et alimentaire d'une haie de Calliandra calothyrsus dans le cadre de systèmes diversifiés polyculture-élevage dans les «Hauts» de la Réunion.
Gilles Mandret, Jacques Tassin
doaj   +1 more source

La composition chimique des espèces pastorales broutées par les caprins au niveau d’un parcours forestier du Parc Naturel de Bouhachem

African and Mediterranean Agricultural Journal - Al Awamia, 2022
Ce travail a pour objectif d’étudier la composition chimique (teneurs en protéines brutes (PB), matière organique (MO), extrait éthéré (EE), glucides pariétaux, et tannins condensés (TC)) de 14 espèces pastorales ligneuses, en plus de la strate herbacée,
Youssef Chebli, Hamza Boulaich, Mouad Chentouf, Samira El Otmani   +3 more
doaj   +1 more source