Results 51 to 60 of about 227,059 (331)

Structures of Three Actinobacteriophage Capsids: Roles of Symmetry and Accessory Proteins

open access: yesViruses, 2020
Here, we describe the structure of three actinobacteriophage capsids that infect Mycobacterium smegmatis. The capsid structures were resolved to approximately six angstroms, which allowed confirmation that each bacteriophage uses the HK97-fold to form ...
Jennifer Podgorski   +6 more
doaj   +1 more source

Simultaneous membrane and RNA binding by tick-borne encephalitis virus capsid protein.

open access: yesPLoS Pathogens, 2023
Tick-borne encephalitis virus is an enveloped, pathogenic, RNA virus in the family Flaviviridae, genus Flavivirus. Viral particles are formed when the nucleocapsid, consisting of an RNA genome and multiple copies of the capsid protein, buds through the ...
Lauri Ilmari Aurelius Pulkkinen   +8 more
doaj   +1 more source

De novo peptide grafting to a self-assembling nanocapsule yields a hepatocyte growth factor receptor agonist

open access: yesiScience, 2021
Summary: Lasso-grafting (LG) technology is a method for generating de novo biologics (neobiologics) by genetically implanting macrocyclic peptide pharmacophores, which are selected in vitro against a protein of interest, into loops of arbitrary protein ...
Yamato Komatsu   +8 more
doaj   +1 more source

Chiral Quasicrystalline Order and Dodecahedral Geometry in Exceptional Families of Viruses

open access: yes, 2012
On the example of exceptional families of viruses we i) show the existence of a completely new type of matter organization in nanoparticles, in which the regions with a chiral pentagonal quasicrystalline order of protein positions are arranged in a ...
C. Janot   +10 more
core   +5 more sources

Density waves theory of the capsid structure of small icosahedral viruses

open access: yes, 2006
We apply Landau theory of crystallization to explain and to classify the capsid structures of small viruses with spherical topology and icosahedral symmetry.
D. L. D. Caspar   +8 more
core   +3 more sources

Force steps during viral DNA packaging ? [PDF]

open access: yes, 2003
Biophysicists and structural biologists increasingly acknowledge the role played by the mechanical properties of macromolecules as a critical element in many biological processes.
Alberts   +29 more
core   +2 more sources

Combinatorial Synthesis of Next Generation Water‐Soluble Quaternized N‐Halamine Oligomers with Long‐Lasting Antiviral Properties

open access: yesAdvanced Functional Materials, EarlyView.
A combinatorial library of dual‐functional antiviral oligomers incorporating N‐halamine and quaternary ammonium functionalities is developed for long‐lasting antiviral activity. The lead materials exhibit rapid and durable antiviral activity against SARS‐CoV‐2 variants and influenza H1N1, with 4 to 5 log reduction in viral copies at 5 mg mL−1 ...
Eid Nassar‐Marjiya   +14 more
wiley   +1 more source

Enhancing Capsid Proteins Capacity in Plant Virus-Vector Interactions and Virus Transmission

open access: yesCells, 2021
Vector transmission of plant viruses is basically of two types that depend on the virus helper component proteins or the capsid proteins. A number of plant viruses belonging to disparate groups have developed unusual capsid proteins providing for ...
Alexey Agranovsky
doaj   +1 more source

Dynamics of Bacteriophage Genome Ejection In Vitro and In Vivo

open access: yes, 2010
Bacteriophages, phages for short, are viruses of bacteria. The majority of phages contain a double-stranded DNA genome packaged in a capsid at a density of ~500 mg/ml. This high density requires substantial compression of the normal B form helix, leading
Molineux, Ian J., Panja, Debabrata
core   +1 more source

Measuring the force ejecting DNA from phage [PDF]

open access: yes, 2004
We discuss how a balance can be established between the force acting to eject DNA from viral capsids and the force resisting its entry into a colloidal suspension which mimics the host cell cytoplasm.
Castelnovo, M.   +3 more
core   +1 more source

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