Results 51 to 60 of about 31,265 (205)

Specific delivery of captopril to the kidney with the prodrug captopril-lysozyme

, 1999
Low-molecular-weight proteins (LMWPs) accumulate in the proximal tubular cells of the kidney, which makes these proteins interesting tools for renal drug targeting.
Meijer, D.K F, de Zeeuw, D; id_orcid, Moolenaar, Frits, Kok, R.J, de Zeeuw, D   +4 more
core   +1 more source

Effects of captopril against radiation injuries in the Göttingen minipig model of hematopoietic-acute radiation syndrome.

PLoS ONE, 2021
Our laboratory has demonstrated that captopril, an angiotensin converting enzyme inhibitor, mitigates hematopoietic injury following total body irradiation in mice.
W Bradley Rittase, Elizabeth A McCart, Jeannie M Muir, Roxane M Bouten, John E Slaven, Ognoon Mungunsukh, Michelle A Bylicky, W Louis Wilkins, Sang-Ho Lee, Kristbjorn O Gudmundsson, Tiziana Di Pucchio, Cara H Olsen, Yang Du, Regina M Day   +13 more
doaj   +1 more source

Determinação de captopril por HPLC acoplado a espectômetro de massa: aplicação em estudo de bioequivalência - doi: 10.5020/18061230.2012.p13

Revista Brasileira em Promoção da Saúde, 2012
Objetivo: Avaliar a bioequivalência de três diferentes formulações de captopril 25mg (Capoten® como formulação de referência e Captopril produzido pela FURP e Farmanguinhos como formulações testes) em 24 voluntários saudáveis de ambos os sexos.
Aline Kércia Alves Soares, Manoel Odorico de Moraes, Fernando Antônio Frota Bezerra, Gilberto de Nucci, Maria Elisabete Amaral de Moraes   +4 more
doaj   +1 more source

The Prescription Pattern, Care‐Seeking Behavior and Glycemic Status Among the Diabetic Patients in a Tertiary‐Level Hospital of Bangladesh: A Cross‐Sectional Observational Study

Health Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims The prevalence of diabetes mellitus is on the rise globally, presenting a significant challenge to healthcare systems, particularly in developing countries like Bangladesh. However, treatment modalities, care‐seeking attitudes and clinical profiles among these patients are not well explored. This descriptive cross‐sectional
Md. Shamsur Rahman Sweet, Shimul Halder, Mst. Rikta Banu, Most. Chand Sultana Khatun, Md. Abdul Muhit   +4 more
wiley   +1 more source

Captopril Pretreatment Produces an Additive Cardioprotection to Isoflurane Preconditioning in Attenuating Myocardial Ischemia Reperfusion Injury in Rabbits and in Humans

Mediators of Inflammation, 2015
Background. Pretreatment with the angiotensin-converting inhibitor captopril or volatile anesthetic isoflurane has, respectively, been shown to attenuate myocardial ischemia reperfusion (MI/R) injury in rodents and in patients.
Yi Tian, Haobo Li, Peiyu Liu, Jun-mei Xu, Michael G. Irwin, Zhengyuan Xia, Guogang Tian   +6 more
doaj   +1 more source

Effects of Combination Therapy with Captopril and Angiotensin II on the Viability of Random-pattern Skin Flaps in Diabetic Rat Model [PDF]

Turkish Journal of Plastic Surgery, 2016
Objective: Diabetes mellitus leads to tissue damage by erythrocyte aggregation and an endothelial dysfunction-mediated disturbance in vascularization. These mechanisms facilitate the formation of skin wounds.
Binevş Heja Aygören, Fatma Öz Atalay, Berna Aytaç Vuruşkan, Selçuk Akın   +3 more
doaj   +1 more source

Long‐Term Effects of Myocardial Injury on 1‐Year Outcomes in Hospital Survivors With COVID‐19: A Prospective Cohort Study

MedComm, Volume 7, Issue 11, November 2026.
Among COVID‐19 patients, myocardial injury was associated with higher 1‐year mortality and MACE, whereas long‐term ACEI/ARB therapy was associated with lower risks. At 1 year, 71.5% of survivors reported symptoms; myocardial injury was linked to more sequelae and poorer quality of life.
Wu He, Qiongyao He, Ke Xu, Gen Li, Yongcui Yan, Bo Yu, Yujing Su, Junfang Wu, Hong Wang, Dao Wen Wang   +9 more
wiley   +1 more source

Determinação condutométrica de captopril em formulações farmacêuticas utilizando sulfato de cobre(II) como titulante Conductometric determination of captopril in pharmaceutical formulations using copper(II) sulphate as titrant

Química Nova, 2008
A simple and rapid conductometric method for captopril determination using copper(II) sulphate solution as titrant was developed. The method was based on the chemical reaction between captopril and Cu(II) ions yielding a precipitate.
Bruna Cláudia Lourenção, Luiz Humberto Marcolino-Junior, Orlando Fatibello-Filho   +2 more
doaj   +1 more source

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, Volume 40, Issue 11, Page 6249-6275, November 2026.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source

Consumption Time of Captopril Influenced the Outcomes of Patients with Stage 1 Hypertension

Pharmacology and Clinical Pharmacy Research, 2017
Differences in drugs consumption time may affect its absorption and metabolism in the body which could lead to differences in its efficacy. For hypertension patients, one of the most frequently used drugs for lowering blood is captopril.
Sulastri Herdaningsih, Ahmad Muhtadi, Keri Lestari   +2 more
doaj   +1 more source