Results 41 to 50 of about 31,265 (205)

Captopril Attenuates Matrix Metalloproteinase-2 and -9 in Monocrotaline-Induced Right Ventricular Hypertrophy in Rats

open access: yesJournal of Pharmacological Sciences, 2008
Little is known about the influence of angiotensin converting enzyme (ACE) inhibitors on matrix metalloproteinase (MMP) in right ventricular remodeling.
Muneyoshi Okada   +5 more
doaj   +1 more source

Promising results of captopril in improving knee arthrofibrosis and cartilage status: an animal model study

open access: yesJournal of Experimental Orthopaedics, 2022
Purpose Several cytokines and growth factors start and progress the destruction process of joint hyaline cartilage and fibrosis formation. Captopril is classified as an Angiotensin‐converting enzyme inhibitor in which several studies revealed that ...
Seyed Ali Hashemi   +4 more
doaj   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

open access: yesAndrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli   +7 more
wiley   +1 more source

SUBLINGUAL CAPTOPRIL - A PHARMACOKINETIC AND PHARMACODYNAMIC EVALUATION

open access: yes, 1991
In this study we compared the pharmacokinetics and pharmacodynamics of captopril after sublingual and peroral administration. Single 25 mg doses of captopril were administered sublingually and perorally on two different occasions in a randomised cross ...
McElnay, James   +6 more
core   +3 more sources

A comparative analysis of cell death signalling in RNA and DNA virus infections and potential inhibitory strategies

open access: yesThe FEBS Journal, EarlyView.
RNA and DNA viruses can manipulate host cell death through various mechanisms. RNA viruses (H1N1, SARS‐CoV‐2) induce acute apoptosis, necroptosis, and pyroptosis to promote rapid viral transmission and epithelial barrier damage. In contrast, DNA viruses (HSV‐1, EBV) regulate these mechanisms to sustain a lytic‐latency cycle, evade immune response and ...
Panagiotis Keramidas   +4 more
wiley   +1 more source

Captopril extended adult lifespan.

open access: yes, 2016
Captopril extended adult lifespan.
Kerry Kornfeld (226655)   +2 more
core   +1 more source

Spectrophotometric method for the determination of Captopril in pharmaceutical formulations

open access: yesمجلة بغداد للعلوم, 2013
A simple, rapid and sensitive spectrophotometric method has been developed for the determination of captopril in aqueous solution. The method is based on reaction of captopril with 2,3-dichloro 1,4- naphthoquinon(Dichlone) in neutral medium to form a ...
Baghdad Science Journal
doaj   +1 more source

Effects of Renin–Angiotensin Inhibitors, Sodium–Glucose Cotransporter 2 Inhibitors, Mineralocorticoid Receptor Antagonists and Glucagon‐Like Peptide 1 Receptor Agonists on Kidney Outcomes in Patients With Type 1 Diabetes: A Systematic Review and Meta‐Analysis

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 12, Page 11320-11327, December 2026.
ABSTRACT Aims While the new kidney protective therapies have transformed chronic kidney disease (CKD) management in patients with Type 2 diabetes mellitus (T2DM), treatment options for CKD in Type 1 diabetes mellitus (T1DM) have remained unchanged for 30 years, limited to renin–angiotensin system inhibitors (RASis).
Frances Perry   +12 more
wiley   +1 more source

Effect of Captopril on Brain Oxidative Damage in Pentylenetetrazole-Induced Seizures in Mice [PDF]

open access: yesPharmaceutical Sciences, 2019
Background: Frequent seizure is followed by overproduction of free radicals and brain oxidative stress. Renin angiotensin system (RAS) has some effects on central nervous system.
Fereshteh Asgharzadeh   +6 more
doaj   +1 more source

Advances in Multidimensional Molecular Mechanisms of Epilepsy and Precision Therapy Strategies

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
Epilepsy arises from a multidimensional network imbalance, integrating genetic, inflammatory, and metabolic disruptions. This complexity drives neuronal hyperexcitability and underpins therapeutic challenges. Our review highlights how emerging precision strategies, from targeted molecular therapies to neuromodulation, offer a transformative path toward
Yimin Han   +7 more
wiley   +1 more source

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