Results 31 to 40 of about 24,656 (219)

Participation of kinins in the inhibitory action of captopril on acute hypertension induced by L-NAME in anesthetized rats

Brazilian Journal of Medical and Biological Research, 1997
The aim of the present study was to investigate the role of bradykinin in the inhibitory action of captopril in hypertension induced by L-NAME in anesthetized rats.
R. Soares de Moura, M. Cardoso
doaj   +1 more source

ACE‐inhibitory peptide Leu‐Tyr‐Ala in skeletal muscle actin exhibits anti‐aging effects through the inhibition of acn‐1 in Caenorhabditis elegans

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Inhibitors of angiotensin‐converting enzyme (ACE) are used in pharmaceuticals and functional foods. Captopril, a well‐known ACE inhibitor, extends the lifespan of the nematode Caenorhabditis elegans. Bioactive peptides derived from food sources are considered safe ACE inhibitors.
Issei Yokoyama, Minori Yamane, Kanaho Watanabe, Abdul Fatah, Yusuke Komiya, Jun Nagasao, Keizo Arihara   +6 more
wiley   +1 more source

Captopril Attenuates Matrix Metalloproteinase-2 and -9 in Monocrotaline-Induced Right Ventricular Hypertrophy in Rats

Journal of Pharmacological Sciences, 2008
Little is known about the influence of angiotensin converting enzyme (ACE) inhibitors on matrix metalloproteinase (MMP) in right ventricular remodeling.
Muneyoshi Okada, Ryuta Kikuzuki, Toshiyuki Harada, Yasutomo Hori, Hideyuki Yamawaki, Yukio Hara   +5 more
doaj   +1 more source

Lipid Profile in Primary Aldosteronism: Cross‐Sectional and Post‐Treatment Analyses

Lipids, EarlyView.
ABSTRACT The relationship between primary aldosteronism (PA) and lipid metabolism remains controversial, with inconsistent findings reported in the literature. This study aimed to clarify PA's impact on the lipid profile using both a cross‐sectional comparison with essential hypertension (EH) controls and a longitudinal within‐patient pre‐post ...
Meriem Yazidi, Arige Abid, Chayma Bel hadj Sliman, Elyes Kamoun, Ibtissem Oueslati, Fatma Chaker, Nadia Khessairi, Melika Chihaoui   +7 more
wiley   +1 more source

Avaliação do potencial de interferência analítica de fármacos na análise química do exame de urina [PDF]

, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Farmácia.O exame de urina proporciona informações sobre patologias renais e do trato urinário, bem como sobre algumas moléstias ...
Colombeli, Adriana Scotti da Silva
core  

In vitro Antioxidant, Acetylcholinesterase, and Amyloid-beta Inhibitory Effects of Captopril, An Angiotensin-Converting Enzyme (ACE) Inhibitor

Biomedical Sciences and Clinical Medicine
Objective This study aims to investigate the potential of captopril, an angiotensin-converting enzyme (ACE) inhibitor, to reduce reactive oxygen species (ROS) production and address critical factors associated with Alzheimer’s disease (AD ...
Raghul Murugan, Vantipalli Raga Sai Harshitha, Royapuram Parthasarathy Parameswari, Anitha Roy   +3 more
doaj   +1 more source

Sustained Release of Captopril Tablet with Floating System Using a Cross-Linked Matrix of Alginate

Kartika: Jurnal Ilmiah Farmasi, 2019
Captopril has a short biological half-life 2-3 hours and has been used for long-term treatment of hypertension. The properties of captopril such as absorbed well in the stomach, freely water-soluble, instability in intestinal environment, and ...
Dhadhang Wahyu Kurniawan, Dike Agus Triyanto, Vitis Vini Fera Ratna Utami   +2 more
doaj   +1 more source

Promising results of captopril in improving knee arthrofibrosis and cartilage status: an animal model study

Journal of Experimental Orthopaedics, 2022
Purpose Several cytokines and growth factors start and progress the destruction process of joint hyaline cartilage and fibrosis formation. Captopril is classified as an Angiotensin‐converting enzyme inhibitor in which several studies revealed that ...
Seyed Ali Hashemi, Ali Azad, Amirhossein Erfani, Reza Shahriarirad, Negar Azarpira   +4 more
doaj   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

Acta Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen, Jari Haukka, Tuomas Lilius, Sirpa Loukovaara   +3 more
wiley   +1 more source

Determinação de captopril por HPLC acoplado a espectômetro de massa: aplicação em estudo de bioequivalência - doi: 10.5020/18061230.2012.p13

Revista Brasileira em Promoção da Saúde, 2012
Objetivo: Avaliar a bioequivalência de três diferentes formulações de captopril 25mg (Capoten® como formulação de referência e Captopril produzido pela FURP e Farmanguinhos como formulações testes) em 24 voluntários saudáveis de ambos os sexos.
Aline Kércia Alves Soares, Manoel Odorico de Moraes, Fernando Antônio Frota Bezerra, Gilberto de Nucci, Maria Elisabete Amaral de Moraes   +4 more
doaj   +1 more source