Results 11 to 20 of about 18,910 (175)

ACE-inhibitory peptide Leu-Tyr-Ala in skeletal muscle actin exhibits anti-aging effects through the inhibition of acn-1 in Caenorhabditis elegans. [PDF]

open access: yesJ Sci Food Agric
Abstract BACKGROUND Inhibitors of angiotensin‐converting enzyme (ACE) are used in pharmaceuticals and functional foods. Captopril, a well‐known ACE inhibitor, extends the lifespan of the nematode Caenorhabditis elegans. Bioactive peptides derived from food sources are considered safe ACE inhibitors.
Yokoyama I   +6 more
europepmc   +2 more sources

Cardiovascular Organoids With Adjustable Endothelial Composition via SOX17-Engineered hPSCs. [PDF]

open access: yesBiotechnol Bioeng
ABSTRACT Organoids are considered a novel modeling platform for studying human biology and advancing health research. With the ability to demonstrate complex 3D structure and multicellular interactions, organoids have advanced studies in all major organs as a reliable model.
Liang PY   +4 more
europepmc   +2 more sources

Effect of Apium graveolens Extract Administration on the Pharmacokinetics of Captopril in the Plasma of Rats

open access: yesScientia Pharmaceutica, 2018
Apium graveolens (celery) is an edible and traditionally medicinal plant that is used worldwide, among others for the treatment of hypertension. Combining celery with antihypertensive drugs can affect the pharmacodynamics and pharmacokinetics of the ...
Siska Siska   +3 more
doaj   +1 more source

The exenatide analogue AC3174 attenuates hypertension, insulin resistance, and renal dysfunction in Dahl salt-sensitive rats

open access: yesCardiovascular Diabetology, 2010
Background Activation of glucagon-like peptide-1 (GLP-1) receptors improves insulin sensitivity and induces vasodilatation and diuresis. AC3174 is a peptide analogue with pharmacologic properties similar to the GLP-1 receptor agonist, exenatide ...
Fernandez Rayne   +5 more
doaj   +1 more source

Physiological and histological effect of Captopril on kidney and the protective role of Brassica nigra seed extract in male rats

open access: yesTikrit Journal of Pure Science, 2020
The experiment was designed to determine the protective role of Brassica nigra seed extract on Kidney function and tissue against the negative effects induced by the drug Captopril (CPT25 and CPT50).
Noor Mukhlis Hamid Al-Qady   +1 more
doaj   +1 more source

Dermatitis to captopril

open access: yesAllergologia et Immunopathologia, 2001
reports on delated cutaneous reactions to captopril have been seldom reported. Captopril is an angiotensin-converting enzyme (ACE) inhibitor and their cutaneous side-effects are documented, but little has been published concerning the usefulness of patch test when they occur. We presented the case of a patient who developed a cutaneous reaction induced
J C, Martínez   +4 more
openaire   +2 more sources

POTENTIATION OF THE HYPOTENSIVE EFFECT OF CAPTOPRIL BY THE H2 BLOCKER CIMETIDINE IN THE NORMOTENSIVE ANAESTHETIZED RATS

open access: yesZagazig Journal of Pharmaceutical Sciences, 1993
The effects of captopril (1 mg/kg), cimetidine (25 mg/kg), and their combination on the arterial blood pressure, heart rate, ECG and the calculated double product of anaesthetized normotensive rats were investigated.
Salah Ghareib   +2 more
doaj   +1 more source

Validation of a liquid chromatographic method for determination of related substances in a candidate certified reference material of captopril

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2011
This paper describes the validation of a reversed-phase high performance liquid chromatography method (RP-HPLC) with diode array detection (DAD) for determination of related substances (impurities from organic synthesis and degradation products) of ...
Raquel Nogueira   +11 more
doaj   +1 more source

Voltammetric Determination of Captopril Using Chlorpromazine as a Homogeneous Mediator

open access: yesInternational Journal of Electrochemistry, 2011
Chlorpromazine was used as a homogeneous electrocatalyst in the oxidation of captopril. The anodic peak current of chlorpromazine was increased substantially in the presence of low concentrations of captopril (pH 4).
Hossein Bahramipur, Fahimeh Jalali
doaj   +1 more source

Electrocatalytic determination of captopril using a carbon paste electrode modified with N-(ferrocenyl methylidene) fluorene-2-amine and graphene/ZnO nanocomposite [PDF]

open access: yesJournal of the Serbian Chemical Society, 2019
A carbon paste electrode (CPE) was modified with N-(ferrocenylmethylidene) fluorene-2-amine and graphene/ZnO nanocomposite. The electrooxidation of captopril (CAP) at the surface of the modified electrode was studied using electrochemical approaches. The
Safaei Mohadeseh   +4 more
doaj   +1 more source

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