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Structural Analysis of the Putative Succinyl-Diaminopimelic Acid Desuccinylase DapE from Campylobacter jejuni: Captopril-Mediated Structural Stabilization [PDF]

Current Issues in Molecular Biology
DapE is a highly conserved bacterial enzyme that produces L,L-diaminopimelic acid in the meso-diaminopimelic acid and lysine synthesis pathway, which is essential for peptidoglycan formation in the cell wall.
Si Yeon Ahn, Young-Bong You, Han Byeol Oh, Min-Ah Park, Sung-il Yoon   +4 more
doaj   +2 more sources

Nifedipine, captopril or sublingual nitroglycerin, which can reduce blood pressure the most?

ARYA Atherosclerosis, 2011
BACKGROUND: Hypertension (HTN) is one of the most important problems in all parts of the world. Although the disease is usually asymptomatic, its diagnosis and treatment are easy.
Ali Maleki, Masoumeh Sadeghi, Mahyar Zaman, Mohammad Javad Tarrahi, Behjat Nabatchi   +4 more
doaj   +2 more sources

Electrocatalytic Determination of Captopril on Gold Nanoparticle-Modified Carbon Paste Electrode. [PDF]

Journal of Optoelectronical Nanostructures, 2022
The electrochemical behavior of captopril at the surface of a carbon-paste electrode (CPE) modified with gold nanoparticles (GNPs) is described. The prepared electrode shows an excellent electrocatalytic activity toward the oxidation of captopril, which ...
Mohamad Ali Zare, Omran Moradlou, Behjat Tahmasebi, Maryam Iranpour, Parisa Farashi   +4 more
doaj   +1 more source

Serum uric acid level and renal function tests in hypertensive patients treated by captopril [PDF]

المجلة العراقية للصيدلة, 2013
Objective: To evaluate the effect of captopril on the serum uric acid level and renal function tests in hypertensive patients, in relation to the age and gender patients , and dose and duration of captopril use.
Dr. Wahda B Al-Youzbaki, Yasir Y T Al-Taee   +1 more
doaj   +1 more source

The efficacy of captopril and 5-fluorouracil combination in the proliferation and collagen deposition of keloid fibroblast

Indonesian Journal of Biotechnology, 2022
Keloid is a benign fibroproliferative tissue growth that exceeds the initial wound margins. Captopril has been tested in vitro to reduce fibroblast proliferation and collagen deposition; thus, it has potential for use in the treatment of keloids ...
Jesslyn Amelia, Yohanes Widodo Wirohadidjojo, Agnes Sri Siswati   +2 more
doaj   +1 more source

Captopril alleviates epilepsy and cognitive impairment by attenuation of C3-mediated inflammation and synaptic phagocytosis

Journal of Neuroinflammation, 2022
Evidence from experimental and clinical studies implicates immuno-inflammatory responses as playing an important role in epilepsy-induced brain injury.
Xinyan Dong, Jianchen Fan, Donghui Lin, Xuehui Wang, Haoyu Kuang, Lifen Gong, Chen Chen, Jie Jiang, Ningxiao Xia, Dahong He, Weida Shen, Peifang Jiang, Rong Kuang, Linghui Zeng, Yicheng Xie   +14 more
doaj   +1 more source

Antagonism of the acute hemodynamic effects of captopril in decompensated congestive heart failure by aspirin administration

Brazilian Journal of Medical and Biological Research, 2003
The concomitant use of angiotensin-converting enzyme inhibitors and aspirin may cause pharmacological antagonism. Hence we examined the effect of aspirin on the neurohormonal function and hemodynamic response to captopril in heart failure patients ...
P.R. Viecili, D. Pamplona, M. Park, S.R. Silva, J.A.F. Ramires, P.L. Da Luz   +5 more
doaj   +1 more source

The effects of docetaxel and/or captopril in expression of TGF-β1, MMP-1, CTGF, and PAI-1 as markers of anterior urethral stricture in an animal model

Therapeutic Advances in Urology, 2020
Background: Treatment of urethral trauma is currently done after urethral stricture occurs. Stricture therapy after occurrence gives unsatisfactory success rates. Several genes, such as transforming growth factor beta 1 (TGF-β1), matrix metalloproteinase 
Wikan Kurniawan, Marsetyawan Heparis Nur Ekandaru Soesatyo, Teguh Aryandono   +2 more
doaj   +1 more source

Captopril Enhances Cardiac Vagal but Not Sympathetic Neurotransmission in Pithed Rats

Journal of Pharmacological Sciences, 2004
The effect of captopril on neurally evoked bradycardia and tachycardia was investigated in pithed rats. Captopril enhanced the vagal nerve stimulation-evoked bradycardia.
Yoshinobu Takata, Takanori Arai, Shigeto Suzuki, Junichi Kurihara, Takashi Uezono, Yoko Okubo, Hitoshi Kato   +6 more
doaj   +1 more source

Captopril oral solution for pediatric use: formulation, stability study and palatability assessment in vivo [PDF]

Brazilian Journal of Pharmaceutical Sciences, 2022
The aim of this work was to develop an oral solution of captopril at 5 mg/mL preservative-free. Two formulations were prepared, one containing sweetener (formulation 1) and the other without this excipient (formulation 2). The results found of validation
Leticia Pereira Dysarz, Melanie Tavares, Alessandra Lifsitch Viçosa, Mara Fernandes Ribeiro, Rafaela Gomes de Silva Teixeira, Sabrina Calil Elias, Márcio Robert Mattos da Silva, Elisabete Pereira dos Santos, Eduardo Ricci-Júnior   +8 more
doaj   +1 more source