Results 201 to 210 of about 158,019 (258)

Artificial intelligence for optimization of immunotherapy: current applications and transformative potential. [PDF]

Front Immunol
Tarhini A, Dave P, Pilon-Thomas S, El Naqa I.   +3 more
europepmc   +1 more source

Physics‐Informed Machine Learning for Sustainable Alloy Design: Toward a Recyclable Unified Q&P Steel

Advanced Science, EarlyView.
A physics‐informed property‐bridging framework links high‐throughput hardness screening to tensile performance in quenching and partitioning steels. By transferring metallurgically guided representations across properties, a single alloy composition is designed to achieve multiple strength grades through heat‐treatment tuning alone, offering a ...
Xiaolu Wei, Yong Li, Chenchong Wang, Lingyu Wang, Xiang Song, Keming Mao, Yu Zhang, Wei Xu   +7 more
wiley   +1 more source

Systematic optimization of PD-L1 and CLDN18.2 CAR-T designs identifies a bicistronic dual-target, double-CD3ζ architecture with enhanced antitumor activity in gastric cancer. [PDF]

Front Immunol
Zhang X, Kong YJ, Li JY, Li HH, Chen L.
europepmc   +1 more source

Imaging‐Guided Live Single‐Cell Lipid Profiling of Leader and Follower Cells During Collective Migration of Triple‐Negative Breast Cancer Cells

Advanced Science, EarlyView.
Integrated single‐cell mass spectrometry reveals distinct lipidomic signatures that differentiate leader and follower phenotypes in migratory breast cancer cells. Phenotype‐specific alterations across various lipid classes, including fatty acids and phosphatidylcholines, underpin functional heterogeneity.
Xiaoyue Huang, Judit González Riera, Mai Nguyen, Jeremy Broekhuis, Sylvia E. Le Dévédec, Ahmed Ali, Thomas Hankemeier   +6 more
wiley   +1 more source

KLF4 overexpression in CAR T cells enhances antitumor potency by preventing exhaustion. [PDF]

J Immunother Cancer
Wang H, Meng X, Feng Y, Su A, Qin W, Shen J, Lu K, Gu L, Ma Y, Wang Y, Mao Y, Ji D, Zong L, Zheng M, Du Y, Cong J, Li J, Wang X.   +17 more
europepmc   +1 more source

A Composite Indicator of Inflammation and Nutritional Status for Predicting Mortality After CABG: The CRP-to-Albumin Ratio. [PDF]

Nutrients
Yımaz S, Söylemez N, Ekici M, Yılmaz M, Sürmeli AO, Toprak B, Karaca Ö, Bora R, Ballı M, Keçeoğlu S.   +9 more
europepmc   +1 more source

Usefulness of serum creatinine-to-albumin ratio for 28-day all-cause mortality in critically ill patients with atrial fibrillation: A retrospective study based on the MIMIC-IV database. [PDF]

Medicine (Baltimore)
Li W, Guo L, Huang H.
europepmc   +1 more source

CAR-neutrophils produced in vivo to treat glioma. [PDF]

Nat Biomed Eng
Chang Y, Shao K, Li H, Jin G, Bentley RT, McCain RR, Crain CJ, Shen J, Tan Y, Liang PY, Harper HA, Torregrosa-Allen S, Elzey BD, Vanhaezebrouck IF, Cohen-Gadol AA, Dong C, Zhu Y, Wang Y, Luo J, Lian XL, Bao X.   +20 more
europepmc   +1 more source

SIRPα ablated iPSC-derived macrophages resist hypophagia and enhance mAb-dependent and CAR-mediated cytotoxicity of solid tumors. [PDF]

Mol Ther Oncol
Smith PR, Kabir ME, Zhang J, Maufort JP, Forsberg MH, Sedzro DM, Berres M, Thomson JA, Capitini CM, Slukvin II.   +9 more
europepmc   +1 more source

MUC1-targeted CAR-T cell secreted anti-PD-1 IgG antibody enhances antitumor activity in Cholangiocarcinoma. [PDF]

Sci Rep
Khuisangeam N, Chinsuwan T, Intanachai T, Thaiwong R, Boonkrai C, Phakham T, Pisitkun T, Suppipat K, Hirankarn N, Tawinwung S.   +9 more
europepmc   +1 more source