Results 161 to 170 of about 14,813,386 (261)
Advanced Materials for Biologics Delivery to Brain Tumors
Advanced Materials, EarlyView.Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng +4 more
wiley +1 more source
reservedNegli ultimi anni, la terapia con cellule CAR-T (acronimo dall’inglese “Chimeric Antigen Receptor T cell therapies” ovvero “Terapie a base di cellule T esprimenti un Recettore Chimerico per Antigene”) si è affermata come uno dei successi piu ...
DINARELLO, ANNA
core
CAR Intrinsic Design Pre-Shapes Transcriptional and Metabolic Networks in CAR T Cells
Background/Objectives: Chimeric antigen receptor (CAR) T cells are a powerful cancer therapy, but their function depends heavily on internal signaling domains and metabolic adaptability.
Didem Agac Cobanoglu +9 more
core +1 more source
Fast Hydrogel Micro‐Actuators Driven by Electric Fields
Advanced Materials, EarlyView.We report the fabrication of chemically programmable electroactuating microstructures through the first integration of two‐photon polymerization with electrically actuated gelatin methacrylate‐based hydrogels. By tailoring the charge of the polymer network, we demonstrate programmable polarity‐dependent bending, enabling microstructures that ...
Annaël Sort‐Montenegro +6 more
wiley +1 more source
Advanced Materials, EarlyView.A sulfur‐doped lignin‐derived carbon‐coated Ni‐NiO‐MoO2 nanorod array was synthesized, exhibiting enhanced UOR performance ‐ due to lattice‐strain and built‐in electric field effects by multiphase heterogeneous interface in Ni‐NiO‐MoO2@SC, excellent corrosion resistance, mass‐transport ability, and long‐term stability (500 mA cm−2 at 1.53 V for 500 h ...
Jiawei Li +9 more
wiley +1 more source
CAR‐T Cells: Future Perspectives
HemaSphere, 2019 Sarah Charrot, Simon Hallam
openaire +3 more sources
Background/Objectives: Esophageal squamous cell carcinoma (ESCC) is a common form of esophageal cancer with a poor prognosis and limited treatment options.
Chenglin Zhang +6 more
core +1 more source
Advanced Materials, EarlyView.Macrophage‐based immunotherapy for solid tumors is limited by poor tracking of cell localization and persistence. This study introduces nanotagged macrophages enabling near‐infrared photoacoustic imaging for real‐time monitoring. IFNγ‐conjugated tags enhance antitumor polarization without harming viability.
Seoyoon Song +8 more
wiley +1 more source
Poly(Alkoxythiophene) Rod‐Coil Block Copolymers for Organic Electrochemical Transistors
Advanced Materials, EarlyView.We present the first synthesis of poly(3‐alkoxythiophene) rod‐coil block copolymers as a new architecture for OMIECs. Incorporating PEG and PLLA coils can enhance device performance beyond the homopolymer. The figure‐of‐merit depends uniquely on coil length.
Junfu Tian +23 more
wiley +1 more source
The Journal of Clinical InvestigationDespite the revolutionary achievements of chimeric antigen receptor (CAR) T cell therapy in treating cancers, especially leukemia, several key challenges still limit its therapeutic efficacy. Of particular relevance is the relapse of cancer in large part
Zheng Fu +23 more
doaj +1 more source