Results 241 to 250 of about 812,191 (301)

AL amyloidosis: a real-world experience with CAR T-cell therapy. [PDF]

Blood Adv
Tan MSY, Warsame R, Parrondo R, Muchtar E, Kourelis T, Buadi F, Gonsalves W, Cook J, Kapoor P, Hayman S, Dingli D, Binder M, Leung N, Roy V, Sher T, Wiedmeier-Nutor JE, Chhabra S, Fonseca R, Abdallah N, Rajkumar SV, Kumar SK, Gertz M, Lin Y, Dispenzieri A.   +23 more
europepmc   +1 more source

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

Advanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li, Junliang Kuang, Dan Zheng, Jieyi Wang, Kun Ge, Chun Qu, Xiaojiao Zheng, Zhenxing Ren, Fengjie Huang, Mingliang Zhao, Yimin Sun, Huiheng Zhang, Keke Ding, Xixi Xia, Yajun Tang, Lu Liu, Jian Zhou, Fei Gao, Xiaohui Ma, Yongquan Xu, Guoxiang Xie, Aihua Zhao, Wei Jia   +22 more
wiley   +1 more source

Wearable Battery‐Free Electrotherapy of Smartsensors for Wound Healthcare

Advanced Science, EarlyView.
Herein, we propose a simple strategy for integrating battery‐free electrotherapy wound dressings with wound sensors. Solid‐state supercapacitors constructed by PMAB with cross‐linked interpenetrating network provide energy for electrotherapy. Meanwhile, excellent mechanical sensing performance of wound dressing was used for wound assessment.
Wenrui Zhang, Qian Lin, Jiancheng Zhang, Hao Mo, Wencheng Li, Yicheng Hu, Hongting Ma, Dan Zhao, Hongnv Yu, Nan Zhu   +9 more
wiley   +1 more source

Humanized and Charge‐Optimized CSPG4‐Specific CAR‐T Cells show Enhanced Efficacy against Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
CSPG4 is identified as a high‐value, stemness‐associated target in HPV‐negative HNSCC. By implementing rational biophysical engineering, a humanized and charge‐optimized CAR is developed to overcome tonic signaling‐induced exhaustion. This strategy induces a profound transcriptomic shift toward a rejuvenated, stem‐like memory state, significantly ...
Xiang Xu, Shizhen Qiu, Zhitong Wang, Dan Li, Min Chen, Yinying Chu, Guangfei Li, Yi Fang, Changjiang Li, Fang Shi, Peijie He, Haitao Wu, Haopeng Wang, Jian Chen   +13 more
wiley   +1 more source

CAR-T cell therapy: A new dawn in the treatment of autoimmune disease. [PDF]

Cell Transplant
Yan S, Zhu X, Xiao Y.
europepmc   +1 more source

Decoding Naturalistic Episodic Memory with Artificial Intelligence and Brain‐Machine Interface

Advanced Science, EarlyView.
Episodic memory weaves together what, where, and when of experience into a personal narrative. Cutting‐edge AI models may decode this intricate process in real‐life settings, revealing how neural activity encodes naturalistic memories. By merging AI with brain–machine interfaces, researchers are edging closer to mapping and even engineering memory ...
Dong Song
wiley   +1 more source

Potential of small-molecule targeted drugs in combination with CAR-T cell therapy for hematologic lymphomas. [PDF]

Front Immunol
Tang W, Yu S.
europepmc   +1 more source

Learnable Diffusion Framework for Mouse V1 Neural Decoding

Advanced Science, EarlyView.
We introduce Sensorium‐Viz, a diffusion‐based framework for reconstructing high‐fidelity visual stimuli from mouse primary visual cortex activity. By integrating a novel spatial embedding module with a Diffusion Transformer (DiT) and a synthetic‐response augmentation strategy, our model outperforms state‐of‐the‐art fMRI‐based baselines, enabling robust
Kaiwen Deng, Peter S. Schwendeman, Yuanfang Guan   +2 more
wiley   +1 more source

Lung tumouroids as a testing platform for precision CAR T cell therapy. [PDF]

Nat Biomed Eng
Ehlen L, Farrera-Sal M, Szyska M, Arndt J, Schallenberg S, Scholz C, Yang M, Vollbrecht C, Löwa A, Friedrich R, Mai M, Peter L, Picht S, Schulenberg S, Geray D, Korus G, Sommerfeld A, Treue D, Strauchmann J, Elsner A, Kath J, Vallone VF, Joosten M, Klatte-Schulz F, Petersen A, Stachelscheid H, Wagner DL, Spies C, Rückert JC, Hocke AC, Polansky JK, Stark R, Klein O, Schmueck-Henneresse M.   +33 more
europepmc   +1 more source

Unaltered NKG2D-CAR T cell function under hypoxia in osteosarcoma in vitro. [PDF]

Cancer Immunol Immunother
Hidalgo L, Garcia-Rodriguez P, Cubillo I, Zubizarreta M, Perez-Martinez A, García-Castro J.   +5 more
europepmc   +1 more source